FINAL Q&A LATEST VERSION
Alcoholic liver disease: etiology, findings, management – ANSWER Most
common cause of cirrhosis
Women twice as sensitive to alcohol toxicity then men
Binge drinking
High mortality rate
Diagnosis on report of alcohol intake, evidence of liver disease, lab abnormalities
AST and ALT often high than 2
Score for mortality: Maddreys' score
- Abstinence
- MDF score greater than 32: prednisone for 4 wks
- May require liver transplant
Wilson's: what, etiology, findings, management - ANSWERFamilial autosomal
recessive disease with neurological symptoms, by chronic liver disease, leading to
cirrhosis. can be lethal. Caused by a lack of a certain gene that causes diminished
excretion of copper into bile. Thus copper injury.
Any pt between 3 and 55 with liver disease without clear cause.
Abnormal aminotransferase
Ceruloplasmin low (less than 50)
24-hr uriary copper: copper greater than 40.
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,Liver biopsy to measure copper
high bilirubin to alkaline phosphatase ratio greater than 2
D-penicillamine, initial ansd maintenance
Zinc, blocks absorption of copper
Avoid food and water with copper
May need liver transplant when cirrhosis is present
Family screening
Fulminant liver failure/ acute liver failure: what, etiology - ANSWER- sudden
impairment of liver cell function
- Hep A, B, C, D, E
- CMV, Epstein-Barr
- drug-induced (Tylenol)
- Toxins (mushrooms)
- Vascular (heat stroke)
- other liver disorders
Acute liver failure: findings, management - ANSWERWeakness, fatigue
weightloss, n/v, abd pain
Change in bowel pattern
- Check BMP, ABG, lactate, toxicology screen, acetaminophen screen, Hep panel,
PT/ INR
- Treat specific etiology:
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,charcoal for acetaminophen and N-acetylcysteine)
Supportive for Hep A and E
Antiviral for Hep B
Test for Wilson
- ICU management: watch for cerebral edema, hyperventilate if present, mannitol.
CT head for encephalopathy
McMurray test, Lachman Test, straight leg test - ANSWERMcMurray: turn foot
and bend knee. Positive with Meniscus injury
Lachman test: Hold upper and lower leg, around knee, stretch. Hyperstretch: ACL
injury
Straight leg test: Pain when raising leg, while supine. Positive for herniated disk.
Dislocation management - ANSWEREarly reduction is essential: closed/ manual
if no fracture. If fracture then may need surgery.
Postreduction immobilization (splint, cast, sling)
surgical repair of ligaments
PT/ OT
NSAIDS
Muscle relaxant for muscle spasms
Narcotics for short term use
Soft tissue injury: definition, classifications, incidence - ANSWERInjury to non-
bony tissue, such as muscle, ligament, tendon, bursa, cartilage, skin
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, Classification:
- Closed injury: contusion, hematoma, crush, strain (muscle), sprain (ligament, first
to third degree), rupture (muscle and ligaments: instability, inability to move)
- Open injury: laceration, abrasion, penetrating/ puncture, amputations
trauma
exercise/ overuse
autoimmune (RA, SLE)
obesity
age (skin tear elderly)
Findings and diagnostics soft tissue injury - ANSWERpain
swelling
feeling of instability of joint
Ruptures/ muscle tear: decreased ROM, immediate swelling and hematoma,
abnormal contour muscle, instability of joint, pain/ guarding, watch neurovascular
integrity
Ligaments/ sprain: pain on palpation and ROM, decreased ROM with moderate
swelling, Lachman's test (hypermobile joint is positive sign)
Strain/ muscle or tendon: swelling, decreased/ absent ROM, pain/ guarding
Cartilage: swelling, click during McMurray's test (would indicate meniscus tear),
pain/ guarding
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