Test Bank For Nuclear Medicine and Pet/CT: Technology and Tec
f f f f f f f f f
hniques 8th Edition By Kristen M. Waterstram-
f f f f f f
Rich, MS, CNMT, NCT, FSNMTS and David Gilmore 978032335622
f f f f f f f f
0 Chapter 1-24 Complete Guide .
f f f f f
1.fWhatfisfthefbasicfprinciplefoffnuclearfmedicine?
A.fAfradiopharmaceuticalfisfadministeredftofthefpatientfandfitfaccumulatesfinftheforganfoffinterest.
B.fGammafraysfemittedfinfallfdirections,fthosefwhichfheadedfinfthefdirectionfoffgammafcamerafwillfenter
thefcrystalfandfundergofScintillations.
C.fAnfimagefoffradiopharmaceuticalfisfformed.
D.fCanfbef2D/fseriesfoffslices.
E.fFusionfoff2fimagesfcanfbefobtainedfbyfPET/CT,fPET/MRIfandfSPECT/CT.
F.fWefcanfcombinefthefradiopharmaceuticalfwithfafcompoundfthatfsuitsfourfpurposef(glucose,
diphosphonates)fandfusefthisfforfvisualization.
G.fNuclearfmedicinefisfafFUNCTIONALfimagingfusedfforfbothfdiagnosticsfandftherapeutic
purposes.f-
fANSWER:fG.fNuclearfmedicinefisfafFUNCTIONALfimagingfusedfforfbothfdiagnosticsfandftherapeutic
purposes.
Whatfisfthefprinciplefandfprocedurefoffanfindirectfvesico-ureteralfrefluxfstudy?f-
fANSWER:fForfdirectfradionuclidefcystography,f99mfTcfpertechnetate,f99mfTc-
DTPA,forf99mfTcfsulphurfcolloidfisfinstilledfthroughfanfindwellingfbladderfcatheter,finfafvolumefoffnormal
fsalinefsufficientftoffillfthefbladder.fInfnormalfpatients,fnofradiopharmaceuticalfrefluxffromfthefbladderfin
tofthefuretersforfthefkidneysfisfseen.f
Thefindirectfradionuclidefcystogramf(IRC)foffersfthefpossibilityfoffdetectingfVURfwithoutfafbladderfcathe
ter,fandfallowsfmicturitionftofbefstudiedfunderfphysiologicalfconditions.fimagingflowfurinaryftractfwhilef
patientfvoids.
Singlefchoice-
fAfterfadministrationfduringfstress,fwhichfradiopharmaceuticalfcanfyoufexpectfredistribution?
(checkfallfthatfapply)f(allf3fradiopharmaceuticalsfarefforfMPI=fMyocardialfPerfusionfImaging).
A.fTc-99mfMIBI.
B.fTI-201fchloride.
C.fTetrofosmin.f-fANSWER:fB.fTI-201fchloride.
Listfatfleastf3fclinicalfindicationfoffstaticfrenalfscintigraphy.f-fANSWER:fA.fUrinaryftractfinfection.
B.fFunction-fevaluationfoffparenchymalfmassf(belowf15%-nonffunctioning).
C.fCongenitalfkidneyfmalformationf(dystrophicfkidney,fsigmoidfhorseshoefkidney).
WefadministerfafhigherftherapeuticfdosefthanfinfdiffusefGraves-Basedowfdiseasefin:
A.fNodularfG-Bfdisease.
B.fAutonomousfadenoma.
C.fBoth.
D.fNeitherfoffthem.f-fANSWER:fC.fBoth.
Whatfisfthefpurposefoffcrystalfinfafgammafcamera?f-fANSWER:fA.fGamma-
fraysfarefemittedfinfallfdirectionsffromftheforganfandfthosefheadingfinfthefdirectionfoffthe
gammafcamerafenterfthefcrystalfandfproducefscintillationsf(lightfproducedfinfaftransparentfmaterialfby
passagefoffafparticle).
B.fThefcrystalfconvertsfgammafrayfintofphotonfwhichfcanfthenfbefmeasured.
SinglefChoice-fThefpatientfshouldffastfforf6fhoursfbeforef(checkfallfapply):
,A.fBonefscintigraphy.
B.fFDGfPET.f-fANSWER:fB.fFDGfPET.f
(QuantificationfisfbyfmaxfSUV-fStandardizedfUptakefValue).
Whichftumorsfcommonlyfmetastasizeftofbone?f(pleaseflistfatfleastf3).f-fANSWER:fA.fBreast.
B.fLung.f(Pulmonary)
C.fProstate.
Bonefscintigraphyfindicationf-fANSWER:fOPRAfFN
osteomyelitis,fprothesisfjointfpain,fRenalforigin-
fosteodystrophyf/fRheumaticfd.,fAsepticfbonefnecrosis,fFracture,fNeoplasmf(1-
fosteosarcoma,fEwing'sfsarcoma)
Complete:fWhatfdofyoufexpectftofseefinfcasefoffhemangiomafinfthefliver?
A.fOnfliverfscintigramfwithflabelledfcolloid:____________
B.fWithflabelledfredfbloodfcells:____________f-
fANSWER:fA.fOnfliverfscintigramfwithflabelledfcolloid:fDeceasedfuptakef(photopenicfarea).
B.fWithflabelledfredfbloodfcells:fPerfusion-fdecreased;fBloodfpool-fincreasedfuptake.f
(Tc-
99fRBCflabelledfSPECTfdemonstratesfdecreasedfactivityfonfinitialfdynamicfimagesffollowedfbyfincreasedf
activityfonfdelayedfbloodfpoolfimages)
HepaticflesionsfwithfTc-99mfColloidfscans.
A.fDecreasedfuptake:
B.fIncreasedfuptake:f-fANSWER:fA.fDecreasedfuptake:
1.fMetastasisf(colon!)
2.fCyst
3.fCirrhosis-Pseudo-tumor.
4.fHepatomaf(Cirrhosis!)
5.fAdenoma
6.fHematoma
7.fHemangiomaf(CavernousfHemangioma-fPhotopenicfdefectfTc-99mfRBC's:fperfusionfdecreased,
bloodfpoolfincreased).
8.fAbscess
B.fIncreasedfuptake-
1.fFNH-fFocalfNodularfHyperplasia.
2.fCirrhosisfwithfregeneratingfnodule.
3.fBudd-Chiarifsyndromef(caudateflobe).
4.fSVNf(superiorfvenafcava)fobstruction
SinglefChoice-fTheflocalizationfoffTc-99mfHMPAOfisfrelatedfto:
A.fAfbreakdownfoffthefbloodfbrainfbarrier.f
B.fCerebralfbloodfflow.f
C.fGlucosefmetabolism.f
D.fInfection/finflammation.f
E.fReceptorfstudies.f
F.fTumorfdetection.f-fANSWER:fB.fCerebralfbloodfflow.
Whatfisfthefdifferencefbetweenfhowfthefthyroidfhandlesfiodinefandfhowfitfhandlesfpertechnetate?f-
fANSWER:fA.fThefthyroidfcanfdoforganificationfoffiodinefbutfnotfpertechnetate.
1.fTc-99fperthechnetatef(IVforfPO)f"Trapping"fonly-
factiveftransportftofthefthyroidfacinarfcells.fImagingf15-30fminfpostfinjection.
, 2.fI-131forfI-
123fsodiumfiodinef(PO)f"Trapping"fandfthenforganificationf(incorporationfoffiodinefintofthyroglobulinffo
rfthefproductionfoffthyroidfhormone)fImagingf24h.
Whichfofftheffollowingfdisordersfarefusuallyfassociatedfwithfanfenhanced
bloodfpoolfonfaflabelledfRBCfstudyfoffthefliver?
A.fSinglefchoice:
1.fHemangioma.
2.fHepatoma.
3.fMetastasesfdisease.
4.fFNH-fFocalfNodularfHyperplasia.
5.f(A)fandf(C).
6.fAllfoffthefabove.f-fANSWER:f1.fHemangioma.
Pleasefprovidefthefmeaningfofftheffollowingfabbreviations:
A.fPET
B.fROI
C.fTc-99mf
D.fSPECTf-fANSWER:fA.fPET:fPositronfEmittingfTomography.
B.fROI:fRegions-Of-Interest
C.fTc-99m:fTechnetium-99fmetastable.
D.fSPECT:fSinglefPhotonfEmittionfcomputeredfTomography.
SinglefChoice-
fAfperfusionflungfscanfshowsfafsegmentalfcoldfdefectfinfthefrightfbasefiffthefventilationfstudy
forfthefsamefpatientfisfnormal,fwhatfisfthefmostfprobablefexplanationfforfthefdefect?f(ventilationfstudy
normal,fperfusionfrightfbasefsegmentalfcoldfdefect)
A.fCOPD.
B.fPulmonaryfembolism.
C.fAttenuationfoffthefheart.
D.fPacemaker.f-fANSWER:fB.fPulmonaryfembolism.f
Acutefpulmonaryfembolism:fVentilation-Normal,fPerfusion-
(multi)segmentalfdefectf(decrease).fVentilation-Perfusionfmismatch.
Infjaundicedfpatients,ftherefisfenhancedfrenalfexcretionfoffHIDAf(HydroxyfImino-
DiaceticfAcid)f(HIDAfScancholescintigraphy
usingfhepatobiliaryfiminodiaceticfacid).fTrue\fFalse?fPleasefexplain.f-fANSWER:fA.fTrue.
B.fHIDAfpharmaceuticalfwouldfaccumulatefinfpolygonalfcallsfandfeventuallyfclearedfthroughfthefbilefcirc
ulation.f
Infhepatitisfthefbilefexcretionfoffthefliverfisfimpaired,fasfisfthefnumberfoffhepatocytes,fwhichfmeansfthatf
morefoffthefpharmaceuticalfwouldfbefclearedfbyfthefkidneys.
A.fInfcasefoffliverfdamageftherefisfnofuptakefoffthefradiopharmaceuticalsfbyfthefKupffer-
cellsfoffthefliverfandftherefwillfbefmorefexcretionfbyfkidney.fIffthefliverfisfhealthy-fthefKupffer-
cellsfwillfuptakefthefradiopharmaceuticalsfandftherefwillfbeflessfexcretionfbyfthefkidney.
InfcasefoffwhatfresultsfobtainedfwithfmyocardialfperfusionfSPECTfwouldfyoufproposefafPETfstudyfoffgluc
ose
metabolism?
A.fSinglefChoice-
1.fNofperfusionfdefect.
2.fDefectfduringfstressfonly.
3.fFixedf(stress+frest)fdefect.f-fANSWER:f3.fFixedf(stress+frest)fdefect.
Explanation:fAbnormalfpumpffunction>needftofdecidefiffandfwhatfcanfwefdof(2foptions:fnothing/
coronarographyfrevascularization).>First:fStress-RestfMPIf(MyocardialfPerfusionfImaging)f3foptional
results:
f f f f f f f f f
hniques 8th Edition By Kristen M. Waterstram-
f f f f f f
Rich, MS, CNMT, NCT, FSNMTS and David Gilmore 978032335622
f f f f f f f f
0 Chapter 1-24 Complete Guide .
f f f f f
1.fWhatfisfthefbasicfprinciplefoffnuclearfmedicine?
A.fAfradiopharmaceuticalfisfadministeredftofthefpatientfandfitfaccumulatesfinftheforganfoffinterest.
B.fGammafraysfemittedfinfallfdirections,fthosefwhichfheadedfinfthefdirectionfoffgammafcamerafwillfenter
thefcrystalfandfundergofScintillations.
C.fAnfimagefoffradiopharmaceuticalfisfformed.
D.fCanfbef2D/fseriesfoffslices.
E.fFusionfoff2fimagesfcanfbefobtainedfbyfPET/CT,fPET/MRIfandfSPECT/CT.
F.fWefcanfcombinefthefradiopharmaceuticalfwithfafcompoundfthatfsuitsfourfpurposef(glucose,
diphosphonates)fandfusefthisfforfvisualization.
G.fNuclearfmedicinefisfafFUNCTIONALfimagingfusedfforfbothfdiagnosticsfandftherapeutic
purposes.f-
fANSWER:fG.fNuclearfmedicinefisfafFUNCTIONALfimagingfusedfforfbothfdiagnosticsfandftherapeutic
purposes.
Whatfisfthefprinciplefandfprocedurefoffanfindirectfvesico-ureteralfrefluxfstudy?f-
fANSWER:fForfdirectfradionuclidefcystography,f99mfTcfpertechnetate,f99mfTc-
DTPA,forf99mfTcfsulphurfcolloidfisfinstilledfthroughfanfindwellingfbladderfcatheter,finfafvolumefoffnormal
fsalinefsufficientftoffillfthefbladder.fInfnormalfpatients,fnofradiopharmaceuticalfrefluxffromfthefbladderfin
tofthefuretersforfthefkidneysfisfseen.f
Thefindirectfradionuclidefcystogramf(IRC)foffersfthefpossibilityfoffdetectingfVURfwithoutfafbladderfcathe
ter,fandfallowsfmicturitionftofbefstudiedfunderfphysiologicalfconditions.fimagingflowfurinaryftractfwhilef
patientfvoids.
Singlefchoice-
fAfterfadministrationfduringfstress,fwhichfradiopharmaceuticalfcanfyoufexpectfredistribution?
(checkfallfthatfapply)f(allf3fradiopharmaceuticalsfarefforfMPI=fMyocardialfPerfusionfImaging).
A.fTc-99mfMIBI.
B.fTI-201fchloride.
C.fTetrofosmin.f-fANSWER:fB.fTI-201fchloride.
Listfatfleastf3fclinicalfindicationfoffstaticfrenalfscintigraphy.f-fANSWER:fA.fUrinaryftractfinfection.
B.fFunction-fevaluationfoffparenchymalfmassf(belowf15%-nonffunctioning).
C.fCongenitalfkidneyfmalformationf(dystrophicfkidney,fsigmoidfhorseshoefkidney).
WefadministerfafhigherftherapeuticfdosefthanfinfdiffusefGraves-Basedowfdiseasefin:
A.fNodularfG-Bfdisease.
B.fAutonomousfadenoma.
C.fBoth.
D.fNeitherfoffthem.f-fANSWER:fC.fBoth.
Whatfisfthefpurposefoffcrystalfinfafgammafcamera?f-fANSWER:fA.fGamma-
fraysfarefemittedfinfallfdirectionsffromftheforganfandfthosefheadingfinfthefdirectionfoffthe
gammafcamerafenterfthefcrystalfandfproducefscintillationsf(lightfproducedfinfaftransparentfmaterialfby
passagefoffafparticle).
B.fThefcrystalfconvertsfgammafrayfintofphotonfwhichfcanfthenfbefmeasured.
SinglefChoice-fThefpatientfshouldffastfforf6fhoursfbeforef(checkfallfapply):
,A.fBonefscintigraphy.
B.fFDGfPET.f-fANSWER:fB.fFDGfPET.f
(QuantificationfisfbyfmaxfSUV-fStandardizedfUptakefValue).
Whichftumorsfcommonlyfmetastasizeftofbone?f(pleaseflistfatfleastf3).f-fANSWER:fA.fBreast.
B.fLung.f(Pulmonary)
C.fProstate.
Bonefscintigraphyfindicationf-fANSWER:fOPRAfFN
osteomyelitis,fprothesisfjointfpain,fRenalforigin-
fosteodystrophyf/fRheumaticfd.,fAsepticfbonefnecrosis,fFracture,fNeoplasmf(1-
fosteosarcoma,fEwing'sfsarcoma)
Complete:fWhatfdofyoufexpectftofseefinfcasefoffhemangiomafinfthefliver?
A.fOnfliverfscintigramfwithflabelledfcolloid:____________
B.fWithflabelledfredfbloodfcells:____________f-
fANSWER:fA.fOnfliverfscintigramfwithflabelledfcolloid:fDeceasedfuptakef(photopenicfarea).
B.fWithflabelledfredfbloodfcells:fPerfusion-fdecreased;fBloodfpool-fincreasedfuptake.f
(Tc-
99fRBCflabelledfSPECTfdemonstratesfdecreasedfactivityfonfinitialfdynamicfimagesffollowedfbyfincreasedf
activityfonfdelayedfbloodfpoolfimages)
HepaticflesionsfwithfTc-99mfColloidfscans.
A.fDecreasedfuptake:
B.fIncreasedfuptake:f-fANSWER:fA.fDecreasedfuptake:
1.fMetastasisf(colon!)
2.fCyst
3.fCirrhosis-Pseudo-tumor.
4.fHepatomaf(Cirrhosis!)
5.fAdenoma
6.fHematoma
7.fHemangiomaf(CavernousfHemangioma-fPhotopenicfdefectfTc-99mfRBC's:fperfusionfdecreased,
bloodfpoolfincreased).
8.fAbscess
B.fIncreasedfuptake-
1.fFNH-fFocalfNodularfHyperplasia.
2.fCirrhosisfwithfregeneratingfnodule.
3.fBudd-Chiarifsyndromef(caudateflobe).
4.fSVNf(superiorfvenafcava)fobstruction
SinglefChoice-fTheflocalizationfoffTc-99mfHMPAOfisfrelatedfto:
A.fAfbreakdownfoffthefbloodfbrainfbarrier.f
B.fCerebralfbloodfflow.f
C.fGlucosefmetabolism.f
D.fInfection/finflammation.f
E.fReceptorfstudies.f
F.fTumorfdetection.f-fANSWER:fB.fCerebralfbloodfflow.
Whatfisfthefdifferencefbetweenfhowfthefthyroidfhandlesfiodinefandfhowfitfhandlesfpertechnetate?f-
fANSWER:fA.fThefthyroidfcanfdoforganificationfoffiodinefbutfnotfpertechnetate.
1.fTc-99fperthechnetatef(IVforfPO)f"Trapping"fonly-
factiveftransportftofthefthyroidfacinarfcells.fImagingf15-30fminfpostfinjection.
, 2.fI-131forfI-
123fsodiumfiodinef(PO)f"Trapping"fandfthenforganificationf(incorporationfoffiodinefintofthyroglobulinffo
rfthefproductionfoffthyroidfhormone)fImagingf24h.
Whichfofftheffollowingfdisordersfarefusuallyfassociatedfwithfanfenhanced
bloodfpoolfonfaflabelledfRBCfstudyfoffthefliver?
A.fSinglefchoice:
1.fHemangioma.
2.fHepatoma.
3.fMetastasesfdisease.
4.fFNH-fFocalfNodularfHyperplasia.
5.f(A)fandf(C).
6.fAllfoffthefabove.f-fANSWER:f1.fHemangioma.
Pleasefprovidefthefmeaningfofftheffollowingfabbreviations:
A.fPET
B.fROI
C.fTc-99mf
D.fSPECTf-fANSWER:fA.fPET:fPositronfEmittingfTomography.
B.fROI:fRegions-Of-Interest
C.fTc-99m:fTechnetium-99fmetastable.
D.fSPECT:fSinglefPhotonfEmittionfcomputeredfTomography.
SinglefChoice-
fAfperfusionflungfscanfshowsfafsegmentalfcoldfdefectfinfthefrightfbasefiffthefventilationfstudy
forfthefsamefpatientfisfnormal,fwhatfisfthefmostfprobablefexplanationfforfthefdefect?f(ventilationfstudy
normal,fperfusionfrightfbasefsegmentalfcoldfdefect)
A.fCOPD.
B.fPulmonaryfembolism.
C.fAttenuationfoffthefheart.
D.fPacemaker.f-fANSWER:fB.fPulmonaryfembolism.f
Acutefpulmonaryfembolism:fVentilation-Normal,fPerfusion-
(multi)segmentalfdefectf(decrease).fVentilation-Perfusionfmismatch.
Infjaundicedfpatients,ftherefisfenhancedfrenalfexcretionfoffHIDAf(HydroxyfImino-
DiaceticfAcid)f(HIDAfScancholescintigraphy
usingfhepatobiliaryfiminodiaceticfacid).fTrue\fFalse?fPleasefexplain.f-fANSWER:fA.fTrue.
B.fHIDAfpharmaceuticalfwouldfaccumulatefinfpolygonalfcallsfandfeventuallyfclearedfthroughfthefbilefcirc
ulation.f
Infhepatitisfthefbilefexcretionfoffthefliverfisfimpaired,fasfisfthefnumberfoffhepatocytes,fwhichfmeansfthatf
morefoffthefpharmaceuticalfwouldfbefclearedfbyfthefkidneys.
A.fInfcasefoffliverfdamageftherefisfnofuptakefoffthefradiopharmaceuticalsfbyfthefKupffer-
cellsfoffthefliverfandftherefwillfbefmorefexcretionfbyfkidney.fIffthefliverfisfhealthy-fthefKupffer-
cellsfwillfuptakefthefradiopharmaceuticalsfandftherefwillfbeflessfexcretionfbyfthefkidney.
InfcasefoffwhatfresultsfobtainedfwithfmyocardialfperfusionfSPECTfwouldfyoufproposefafPETfstudyfoffgluc
ose
metabolism?
A.fSinglefChoice-
1.fNofperfusionfdefect.
2.fDefectfduringfstressfonly.
3.fFixedf(stress+frest)fdefect.f-fANSWER:f3.fFixedf(stress+frest)fdefect.
Explanation:fAbnormalfpumpffunction>needftofdecidefiffandfwhatfcanfwefdof(2foptions:fnothing/
coronarographyfrevascularization).>First:fStress-RestfMPIf(MyocardialfPerfusionfImaging)f3foptional
results:
