Progressive Neurodegenerative Disorders (PNDs)
1. debilitating immunological and neurodegenerative disorder: multiple sclero- sis
2. which PNS is characterized by chronic inflammation and diffuse demylin- ization of white matter an d
possibly in gray matter?: multiple sclerosis
3. what is the term for when a persons own body attacks the myelin?: immuno- logical
4. multiple sclerosis results in...: scar tissue formation or sclerotic plaques that reduce axons ability to conduct
impulses
5. what is the cause of MS?: unknown
6. the multifactorial model of MS includes...: combo of genetics, epigenetics, infections(EBV), nutrition,
climate, environment, sunlight exposure (vit. D)
7. MS etiology involves a - family rate of 20-30%, which means that a degree relative is
greater than a ): poly-genetic; 1st; distant
8. how do genes affect MS?: changes happen to the genes that are involved in the immune system
9. what is the most common neuro dx. among adults under 40yrs?: MS
10.there is estimated affected by MS and it is unevenly distributed
throughout the world.: 730,000
11.what increases the risk of MS?: high latitudes and increased distance from the equator (low sun and vit. D)
12.what is the ratio of males to females in MS?: 2-3:1
13.what are the visual disturbances associated with MS?: diplopia, blurred vision, scotoma, pain behind eyes
14.what is the most debilitating and common complaint of MS?: fatigue
15.what percentage of people with MS have cognitive deficits?: 40-70%
16.What are the sensory disturbances that are associated with MS?: numb- ness/ distorted sensation
17.what are the psychosocial signs and symptoms associated with MS?: de- pression, personality changes,
euphoria
18.How is MS diagnosed?: clinically, imaging, lab evidence; excluding any other possible disease/disorder; btw 20-
40 yrs
19.what is benign MS characterized by?: 1-2 episode with no residual impair- ments
20.what is relapsing-remitting-nonprogressive MS characterized by?: return to previous level of function
21.what is relapse-remitting-progressive MS characterized by?: residual im- pairment with each remission
22.what is primary progressive MS characterized by?: steady decline
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1. debilitating immunological and neurodegenerative disorder: multiple sclero- sis
2. which PNS is characterized by chronic inflammation and diffuse demylin- ization of white matter an d
possibly in gray matter?: multiple sclerosis
3. what is the term for when a persons own body attacks the myelin?: immuno- logical
4. multiple sclerosis results in...: scar tissue formation or sclerotic plaques that reduce axons ability to conduct
impulses
5. what is the cause of MS?: unknown
6. the multifactorial model of MS includes...: combo of genetics, epigenetics, infections(EBV), nutrition,
climate, environment, sunlight exposure (vit. D)
7. MS etiology involves a - family rate of 20-30%, which means that a degree relative is
greater than a ): poly-genetic; 1st; distant
8. how do genes affect MS?: changes happen to the genes that are involved in the immune system
9. what is the most common neuro dx. among adults under 40yrs?: MS
10.there is estimated affected by MS and it is unevenly distributed
throughout the world.: 730,000
11.what increases the risk of MS?: high latitudes and increased distance from the equator (low sun and vit. D)
12.what is the ratio of males to females in MS?: 2-3:1
13.what are the visual disturbances associated with MS?: diplopia, blurred vision, scotoma, pain behind eyes
14.what is the most debilitating and common complaint of MS?: fatigue
15.what percentage of people with MS have cognitive deficits?: 40-70%
16.What are the sensory disturbances that are associated with MS?: numb- ness/ distorted sensation
17.what are the psychosocial signs and symptoms associated with MS?: de- pression, personality changes,
euphoria
18.How is MS diagnosed?: clinically, imaging, lab evidence; excluding any other possible disease/disorder; btw 20-
40 yrs
19.what is benign MS characterized by?: 1-2 episode with no residual impair- ments
20.what is relapsing-remitting-nonprogressive MS characterized by?: return to previous level of function
21.what is relapse-remitting-progressive MS characterized by?: residual im- pairment with each remission
22.what is primary progressive MS characterized by?: steady decline
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