PCEUT 531 Set Exam
Tested Questions & Reviewed Correct
Detailed Answers
New Update Study Material!!
1. Define powders - ANSWER
dry, finely divided drugs intended for internal or external use
2. Pharmaceutical significance of powders - ANSWER
1. important physical form: used for caps/tabs and added to susp,oint,supp, etc.
2. dissolution rate of powder increases as particle size decreases --> improves
drug bioavailability
3. manufactured as granules that can be made into liquid forms
4. drugs are more stable as dry solids: easier storage, palatability, accurate
dosing/controlled release formulations
3. Types of powders - ANSWER Very coarse to very fine, based on particle size
4. Pharmaceutical applications of powders - ANSWER
-external (topical)
-internal (oral)
, -tabs/caps: increases accurate dosing for more potent drugs
-if patient cant swallow --> divided powders
-primary ingredient in most oral drugs
5. extemporaneous techniques of powders - ANSWER -comminution
-trituration
-geometric dilution
-levigation
6. Comminution - ANSWER reducing size of particles/aggregates to fine
powders usually on a large scale
7. Trituration - ANSWER reducing particle size and mixing 2+ powders with a
mortar and pestle usually on small scale
types:
-pulverization by intervention
-levigation
pulverization by intervention
triturating
8. Adding solvent that can be evaporated; when drugs have crystalline structure
that doesn't crush easily - ANSWER
levigation
triturating
. Adding non-solvent that remains in the final product
geometric addition/dilution
mixing 2+ powders of unequal quantities
ensures uniform distribution of small quantities of powdered drug
Tested Questions & Reviewed Correct
Detailed Answers
New Update Study Material!!
1. Define powders - ANSWER
dry, finely divided drugs intended for internal or external use
2. Pharmaceutical significance of powders - ANSWER
1. important physical form: used for caps/tabs and added to susp,oint,supp, etc.
2. dissolution rate of powder increases as particle size decreases --> improves
drug bioavailability
3. manufactured as granules that can be made into liquid forms
4. drugs are more stable as dry solids: easier storage, palatability, accurate
dosing/controlled release formulations
3. Types of powders - ANSWER Very coarse to very fine, based on particle size
4. Pharmaceutical applications of powders - ANSWER
-external (topical)
-internal (oral)
, -tabs/caps: increases accurate dosing for more potent drugs
-if patient cant swallow --> divided powders
-primary ingredient in most oral drugs
5. extemporaneous techniques of powders - ANSWER -comminution
-trituration
-geometric dilution
-levigation
6. Comminution - ANSWER reducing size of particles/aggregates to fine
powders usually on a large scale
7. Trituration - ANSWER reducing particle size and mixing 2+ powders with a
mortar and pestle usually on small scale
types:
-pulverization by intervention
-levigation
pulverization by intervention
triturating
8. Adding solvent that can be evaporated; when drugs have crystalline structure
that doesn't crush easily - ANSWER
levigation
triturating
. Adding non-solvent that remains in the final product
geometric addition/dilution
mixing 2+ powders of unequal quantities
ensures uniform distribution of small quantities of powdered drug
