Definitive Solution/ 2024-2025.
What drugs should be avoided with Kava Kava? - Answer: Alprazolam
CNS depressants (e.g., phenobarbital, zolpidem)
What is the normal range for TSH? - Answer: 0.5 - 5.0 mu/L
What are lab values in Hyperthyroidism - Answer: Decreased TSH
Increased T4 and T3
What are labs in Hypothyroidism? - Answer: Increased TSH
Decreased T4 and T3
What are 5 primary symptoms of Hyperthyroidism? - Answer: Heat intolerance
Agitation, Anxiety, Irritability
Tachycardia
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,Mood swings
Weight loss
What are 4 primary symptoms of Hypothyroidism? - Answer: Cold intolerance
Lethargy
Weight gain
Decreased libido
Hypothyroidism mimics symptoms of what psychiatric disorder? - Answer: Depression
Hyperthyroidism mimics symptoms of what psychiatric disorder? - Answer: Mania
Valproic acid produces what teratogenic effect? - Answer: Spina bifida (neural tube defect)
What is the primary organ where valproic acid is toxic? - Answer: Liver (hepatoxicity)
What are 4 signs of hepatoxicity? - Answer: Abdominal pain in the URQ
Reddish-brown urine
Yellowing of the skin and sclera
Fatigue
What is the therapeutic range for valproic acid? - Answer: 50-125 mcg/ml
What is a toxic level of valproic acid? - Answer: >150 mcg/ml
What are 4 signs of valproic acid toxicity? - Answer: Disorientation
Lethargy
Respiratory depression
Nausea/vomiting
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,A pt on Depakote C/O Abdominal pain in the URQ and Reddish-brown urine. What do you
suspect? What do you do? - Answer: Hepatotoxicity; hold med, draw LFT's (priority), DVP level
With suspected toxicity with valproic acid, what steps/labs should be drawn? - Answer: D/C
drug
Check drug level
Obtain LFTs
Obtain ammonia level
A pregnant pt is taking accutane, zyprexa and abilify; what med needs to be d/c'd? - Answer:
Accutane (used for acne; Causes birth Defects!!!)
What herbal supplement is used for anxiety, stress, and insomnia? What is the major side effect
with Kava Kava? - Answer: Kava Kava
liver damage
What are 5 symptoms of Stephen's Johnson Syndrome? - Answer: Fever -Key sx to suspect SJS;
high yield (HY)
burning of mouth/eyes -HY
Body aches
Severe red rash
Peeling skin
Facial and tongue swelling
Which mood stabilizer causes the least weight gain? - Answer: Lamotrigine (Lamictal)
Which 3 SGAs cause the least weight gain? - Answer: Lurasidone (Latuda)
Aripiprazole (Abilify)
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, Ziprasidone (Geodon)
Which SGA is the least sedating? - Answer: Aripiprazole (Abilify)
Your pt is taking Kava and you need to add an AS to manage their SCZ, which do you add? -
Answer: Aripiprazole (least sedating)
What are 2 hallmark symptoms of delirium? - Answer: Acute onset
disturbance of LOC
impaired cognition
inattention
How are agitation and psychotic symptoms treated in delirium? - Answer: Low dose Haldol (QTc
check first)
16 y/o C/O feeling funny after inhaling Acetone (nail polish remover). What is your action? -
Answer: Do UDS; chances are they may be abusing other substances
What 4 drugs can cause mania? - Answer: "SAID"
Steroids
Antidepressants (in BPD)
Isoniazid (INH)
Disulfiram (Antabuse)
What 6 drugs can induce depression? - Answer: "SIP BARB"
Steroids
Interferon,
Progesterone
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