NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY MIDTERM
EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT|
MOST RECENT WALDEN UNIVERSITY|ALREADY GRADED A+.
Combining these substances with Cytochrome P450 enzyme
inhibitors can result in severe respiratory depression and death
due to toxic levels: - ANSWER Ethanol and sedative hypnotics
(benzos)
Which type of Antipsychotics are preferred? Typical (first-
generation) or Atypical (second generation): - ANSWER -Atypical
(second generation)
Eight common Atypical Antipsychotics: - ANSWER -clozapine,
olanzapine, quetiapine, paliperidone, risperidone, lurasidone,
ziprasidone, aripiprazole This Atypical Antipsychotic uniquely
partially stimulates D2 and 5-HT1 receptors: - ANSWER -
Aripiprazole
Five other indications for Atypical Antipsychotics: - ANSWER -
Bipolar disorder, OCD, Anxiety, Depression, Tourette Syndrome
,First line agent for Acute Mania: - ANSWER -Atypical
Antipsychotics
Because they also block D2 receptors in the tuberoinfundibular
pathway Atypical Antipsychotics can cause: - ANSWER -
Hyperprolactinemia
Hyperprolactinemia caused by Atypical Antipsychotics blocking
D2 receptors in the tuberoinfundibular pathway can result in
these three side effects: - ANSWER -Oligomenorrhea,
Galactorrhea, and Gynecomastia
Because of its effect on blocking dopamine receptors in the
tuberoinfundibular pathway, this Atypical Antipsychotic is the
most likely to cause
Hyperprolactinemia (oligomennorhea, galactorrhea, and
gynecomastia): - ANSWER -risperidone
Atypical Antipsychotics also block Dopamine receptors in the
Nigrostriatal pathway and can cause these symptoms: -
ANSWER -Extrapyramidal symptoms (dyskinesias and dystonic
reactions, tardive dyskinesia, pseudoparkinsonism, akinesia,
akathisia, and neuroleptic malignant syndrome)
, Acute extrapyramidal symptoms include: - ANSWER -Dystonia,
Akathisia, and
Pseudoparkinsonism
Tardive (delayed) extrapyramidal symptoms include: - ANSWER
-Tardive
Dyskinesia and Neuroleptic Malignant Syndrome
This generation of Antipsychotics binds more loosely to D2
receptors and can get "kicked off' if there is a lot of Dopamine
around resulting in less extrapyramidal symptoms: - ANSWER -
Second-Generation Antipsychotics (Atypical)
14. First generation Antipsychotics (Typical) bind more tightly to
D2 receptors and are not "kicked off" when excess Dopamine is
around. This characteristic makes them more likely to cause: -
ANSWER -Extrapyramidal Symptoms (dyskinesias and dystonic
reactions, tardive dyskinesia, pseudoparkinsonism, akinesia,
akathisia, and neuroleptic malignant syndrome)
Less severe neurotransmitter side effects of Atypical
Antipsychotics include: -
ANSWER -ORTHOSTATIC HYPOTENSION (Alpha-1 receptor
inhibition), ANTICHOLINERGIC SIDE EFFECTS (muscarinic
receptor inhibition), and SEDATION (H1 receptor inhibition).
EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT|
MOST RECENT WALDEN UNIVERSITY|ALREADY GRADED A+.
Combining these substances with Cytochrome P450 enzyme
inhibitors can result in severe respiratory depression and death
due to toxic levels: - ANSWER Ethanol and sedative hypnotics
(benzos)
Which type of Antipsychotics are preferred? Typical (first-
generation) or Atypical (second generation): - ANSWER -Atypical
(second generation)
Eight common Atypical Antipsychotics: - ANSWER -clozapine,
olanzapine, quetiapine, paliperidone, risperidone, lurasidone,
ziprasidone, aripiprazole This Atypical Antipsychotic uniquely
partially stimulates D2 and 5-HT1 receptors: - ANSWER -
Aripiprazole
Five other indications for Atypical Antipsychotics: - ANSWER -
Bipolar disorder, OCD, Anxiety, Depression, Tourette Syndrome
,First line agent for Acute Mania: - ANSWER -Atypical
Antipsychotics
Because they also block D2 receptors in the tuberoinfundibular
pathway Atypical Antipsychotics can cause: - ANSWER -
Hyperprolactinemia
Hyperprolactinemia caused by Atypical Antipsychotics blocking
D2 receptors in the tuberoinfundibular pathway can result in
these three side effects: - ANSWER -Oligomenorrhea,
Galactorrhea, and Gynecomastia
Because of its effect on blocking dopamine receptors in the
tuberoinfundibular pathway, this Atypical Antipsychotic is the
most likely to cause
Hyperprolactinemia (oligomennorhea, galactorrhea, and
gynecomastia): - ANSWER -risperidone
Atypical Antipsychotics also block Dopamine receptors in the
Nigrostriatal pathway and can cause these symptoms: -
ANSWER -Extrapyramidal symptoms (dyskinesias and dystonic
reactions, tardive dyskinesia, pseudoparkinsonism, akinesia,
akathisia, and neuroleptic malignant syndrome)
, Acute extrapyramidal symptoms include: - ANSWER -Dystonia,
Akathisia, and
Pseudoparkinsonism
Tardive (delayed) extrapyramidal symptoms include: - ANSWER
-Tardive
Dyskinesia and Neuroleptic Malignant Syndrome
This generation of Antipsychotics binds more loosely to D2
receptors and can get "kicked off' if there is a lot of Dopamine
around resulting in less extrapyramidal symptoms: - ANSWER -
Second-Generation Antipsychotics (Atypical)
14. First generation Antipsychotics (Typical) bind more tightly to
D2 receptors and are not "kicked off" when excess Dopamine is
around. This characteristic makes them more likely to cause: -
ANSWER -Extrapyramidal Symptoms (dyskinesias and dystonic
reactions, tardive dyskinesia, pseudoparkinsonism, akinesia,
akathisia, and neuroleptic malignant syndrome)
Less severe neurotransmitter side effects of Atypical
Antipsychotics include: -
ANSWER -ORTHOSTATIC HYPOTENSION (Alpha-1 receptor
inhibition), ANTICHOLINERGIC SIDE EFFECTS (muscarinic
receptor inhibition), and SEDATION (H1 receptor inhibition).
