Immunizations NAPLEX 2025 Questions With All Correct
Answers
Who approves the indication for vaccine based on the demonstrated safety
and efficacy ? correct answer -FDA
Who provides recommendations for vaccine administration? correct answer
-Advisory Committee on Immunization Practices (ACIP)
Who approves the ACIP recommendations? correct answer -CDC( Centers
for diseases control and prevention)
Where is the vaccination info found? correct answer -The pink book or
morbidity and mortality weekly report (MMWR)
presence of antigens leads to correct answer -Antibodies
( immunoglobulin)
active immunity correct answer -When a person's own immune system
creates antibodies ( in response to a vaccine or infection)
Last longtime of life long
passive immunity correct answer -Acquired when antibodies are provided
by someone else
Examples : mother gives baby a copy of immunoglobulin shortly after birth
IV immunoglobulin ( IVIG) provides already made antibodies , and can be
used as quick immunity after exposure
Live attenuated (weekend )vaccines correct answer -They have ability to
replicate (grow) and produce immunity but usually do not cause illness
They produce strong immune response to vaccine
Contraindication to live vaccine correct answer -Immunocompromised ,
and pregnancy since uncontrolled replication f vaccine can occur
Inactivated vaccines correct answer -Contain of either a whole virus or
bacterium or fracture of either
, It's immunity diminishes over time and requires supplemental doses
( booster)
Inactivated vaccines correct answer -Are killed version PF a wild virus or
bacteria that causes the diseases
They cannot replicate
Limitations: immunity not as strong as live vaccine
Booster may be required
Polysaccharides, conjugate and recombinant vaccines correct answer -
Target section of the organism such as protein , sugar or capsid
Polysaccharides vaccines correct answer -They do not provide a good
immune response in children <2yrs e.g pneumococcal polysaccharide
( pneumovax 23)
Conjugate vaccines correct answer -Uses polysaccharide molecules form
the outside layer of encapsulated bacteria and join the molecule to carrier
proteins. Conjugation increases immune response in infants and the antibody
booster response to multiple doses of vaccine
Example : pneumococcal conjugate vaccine ( Prevnar 13)
recombinant vaccines correct answer -A gene segment of a protein from
the organism is inserted into the gene of another cell, such as a yeast cell,
where it replicates
E.g human papillomavirus vaccine
Influenza vaccine (FluBlok Quadrivalent)
Toxoid vaccines correct answer -targets a toxin produced by the disease
E.g diphtheria toxoid vaccine , tetanus
mRNA vaccine correct answer -The vaccine gives instruction to the body
cell to produce a protein specific to the pathogen, which then triggers immune
response
Live vaccines correct answer -Live vaccine are most similar to the actual
diseases and provide a strong, long lasting immune response
Answers
Who approves the indication for vaccine based on the demonstrated safety
and efficacy ? correct answer -FDA
Who provides recommendations for vaccine administration? correct answer
-Advisory Committee on Immunization Practices (ACIP)
Who approves the ACIP recommendations? correct answer -CDC( Centers
for diseases control and prevention)
Where is the vaccination info found? correct answer -The pink book or
morbidity and mortality weekly report (MMWR)
presence of antigens leads to correct answer -Antibodies
( immunoglobulin)
active immunity correct answer -When a person's own immune system
creates antibodies ( in response to a vaccine or infection)
Last longtime of life long
passive immunity correct answer -Acquired when antibodies are provided
by someone else
Examples : mother gives baby a copy of immunoglobulin shortly after birth
IV immunoglobulin ( IVIG) provides already made antibodies , and can be
used as quick immunity after exposure
Live attenuated (weekend )vaccines correct answer -They have ability to
replicate (grow) and produce immunity but usually do not cause illness
They produce strong immune response to vaccine
Contraindication to live vaccine correct answer -Immunocompromised ,
and pregnancy since uncontrolled replication f vaccine can occur
Inactivated vaccines correct answer -Contain of either a whole virus or
bacterium or fracture of either
, It's immunity diminishes over time and requires supplemental doses
( booster)
Inactivated vaccines correct answer -Are killed version PF a wild virus or
bacteria that causes the diseases
They cannot replicate
Limitations: immunity not as strong as live vaccine
Booster may be required
Polysaccharides, conjugate and recombinant vaccines correct answer -
Target section of the organism such as protein , sugar or capsid
Polysaccharides vaccines correct answer -They do not provide a good
immune response in children <2yrs e.g pneumococcal polysaccharide
( pneumovax 23)
Conjugate vaccines correct answer -Uses polysaccharide molecules form
the outside layer of encapsulated bacteria and join the molecule to carrier
proteins. Conjugation increases immune response in infants and the antibody
booster response to multiple doses of vaccine
Example : pneumococcal conjugate vaccine ( Prevnar 13)
recombinant vaccines correct answer -A gene segment of a protein from
the organism is inserted into the gene of another cell, such as a yeast cell,
where it replicates
E.g human papillomavirus vaccine
Influenza vaccine (FluBlok Quadrivalent)
Toxoid vaccines correct answer -targets a toxin produced by the disease
E.g diphtheria toxoid vaccine , tetanus
mRNA vaccine correct answer -The vaccine gives instruction to the body
cell to produce a protein specific to the pathogen, which then triggers immune
response
Live vaccines correct answer -Live vaccine are most similar to the actual
diseases and provide a strong, long lasting immune response
