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BIOCHEMISTRY LECTURE

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BIOCHEMISTRY FOR MEDICAL LABORATORY
SCIENCE [LEC]
MLSBCHMC | LESSON 1

LESSON 1: INTRODUCTION TO BIOHEMISTRY

BIOCHEMISTRY o Discovery of the role of enzymes as
catalysts.
BIOCHEMISTRY o Identification of nucleic acids as
• Science concerned with the chemical basis information molecules.
of life.
• Science concerned with various molecules 1937 – SIR HANS ADOLF KREBS
that occur in living cells and organisms and (GERMAN)
with their chemical reaction. • Discovered Citric Acid
Cycle.
What is BIOCHEMISTRY? • Won Nobel Prize in
• Medical students who acquire a sound Physiology or Medicine in
knowledge of biochemistry will be in a strong 1953.
position to deal with two central concerns of
the health sciences: 1953 – JAMES WATSON
o The understanding and maintenance AND FRANCIS CRICK
of health (ENGLISH)
o The understanding and effective • Discovered DNA as
treatment of disease double helix.
• Won Nobel Prize in
AIM Physiology or Medicine in 1962.
• To describe and explain, in molecular terms,
1955 – FREDERICK SANGER
all chemical processes of living cells.
(BRITISH)
o Structure – function
o Metabolism and Regulation • Determined Insulin
o How life began? sequence and structure
of proteins.
SIGNIFICANCE • Won Noble Prize in
Physiology or Medicine in
• Essential to all life sciences as the common 1956.
knowledge.
o Genetics, Cell Biology, Molecular 1980 – FREDERICK SANGER
Biology (GERMAN) AND WALTER
o Physiology and Immunology GILBERT (AMERICAN)
o Pharmacology and Pharmacy • Determined sequence
o Toxicology, Pathology, Microbiology of DNA.
o Zoology and Botany • Won Nobel Prize in Chemistry in 1980.
HISTORY AND DEVELOPMENT 1993 – KARY MULLIS
(AMERICAN)
1903 – CARL NEUBERG (GERMAN)
• Invention of PCR Method
• Pioneer (used during Covid
• Father of Biochemistry pandemic).
• Editor of first journal of • Won Nobel Prize in
Biochemistry Chemistry in 1993.
• Notable Breakthroughs:
1|P a g e | B S T

BACHELOR OF SCIENCE IN MEDICAL TECHNOLOGY

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