Which of the following best describes the federally mandated "alternatives
search" in an animal protocol? correct answer -To search for procedures
that may replace the use of animals, reduce the number of animals used, or
refine the methodology to minimize animal pain or distress.
Which of the following best summarizes the information that must be
provided when a database search is used to document a lack of alternatives?
correct answer -The names of the databases used, the date of the search, the
years of citations accessed, and the search strategy.
Which is TRUE regarding thermal support for rats during anesthesia?
correct answer -Rats lose body heat rapidly under anesthesia
Generally there is no need to withhold food or water from rats before surgery
because: correct answer -Rats are physiologically unable to vomit; they
have no risk for respiratory aspiration of vomitus under anesthesia.
Which statement is TRUE regarding the assessment of pain or distress in rats?
correct answer -A rat with a mildly to moderately painful condition may
appear and behave normally.
Which statement is TRUE regarding venipuncture procedures in rats?
correct answer -Because of potential damage to the heart, blood collection
by cardiac puncture is commonly permitted only as a terminal procedure.
Which statement is TRUE regarding anesthesia in rats? correct answer -
Gas anesthesia (using a vaporizer) is generally optimal for providing extended
anesthesia.
Which concept is most relevant to the proper conduct of euthanasia? correct
answer -The selection of an appropriate euthanasia method should address
considerations of humaneness to the animal, and safety for the staff and
onlookers and esthetics for the staff.