©Jason MacConnell 2025 ALL RIGHTS RESERVED.
BOC Immunology Exam Questions With
Correct Answers A+
What are antinuclear antibody tests used for?
a. To determine sensitivities for microbiology
b. To diagnose anemias
c. To diagnose lupus erythematosus
d. To determine PCR analysis - Answer✔c
SLE patients often have:
a. High titers of antimitochondrial antibody
b. Decrease immunoglobulin levels
c. Hight tiers of anti-smooth muscle antibodies
d. High tiers of DNA antibody - Answer✔d
Rheumatoid factor reacts with:
a. Latex particles coated with an inert substance
b. Kinetoplasts of Crithidia luciliae
c. Gamma globulin-coated particle
d. Rh positive erythrocytes - Answer✔c
Positive rheumatoid factor is generally associated with:
a. Anemia
b. Hyperglobulinemia
c. Azotemia
d. Decreased ESR - Answer✔b
Rheumatoid factors are defined as:
, ©Jason MacConnell 2025 ALL RIGHTS RESERVED.
a. Antigens found in patients with RA
b. Autoantibodies with specificity for the Fc portion of the immunoglobulin (IgG) molecule
c. Antibodies that bind to circulating IgM antibodies
d. Are identical to the rheumatoid arthritis precipitin - Answer✔b
High titers of antimicrosomal antibodies are most often found in :
a. Rheumatoid arthritis
b. SLE
c. Hepatitis
d. Thyroid disease - Answer✔d
If an acute serum titer was 1:4 and the convalescent titer was 1:32, what is the best
interpretation?
a. The test should be repeated
b. The results are inconclusive since the titer went up instead of down
c. The patient had a previous infection
d. The patient has an active infection - Answer✔d
What is the labeled antibody in the indirect immunofluorescence method of antibody detection?
a. Complement
b. Anti-human immunoglobulin
c. Rheumatoid factor
d. Human anti-goat immunoglobulin - Answer✔d
A substrate is first exposed to a patient's serum, then after washing, anti-human immunoglobulin
labeled with a fluorochrome is added. What is this procedure called?
a. Fluorescence inhibition
b. Direct fluorescence
c. Indirect fluorescence
d. Fluorescent quenching - Answer✔c
What is Avidity?
a. Degree of hemolysis
b. Titer of an antigen
c. Dilution of an antibody
BOC Immunology Exam Questions With
Correct Answers A+
What are antinuclear antibody tests used for?
a. To determine sensitivities for microbiology
b. To diagnose anemias
c. To diagnose lupus erythematosus
d. To determine PCR analysis - Answer✔c
SLE patients often have:
a. High titers of antimitochondrial antibody
b. Decrease immunoglobulin levels
c. Hight tiers of anti-smooth muscle antibodies
d. High tiers of DNA antibody - Answer✔d
Rheumatoid factor reacts with:
a. Latex particles coated with an inert substance
b. Kinetoplasts of Crithidia luciliae
c. Gamma globulin-coated particle
d. Rh positive erythrocytes - Answer✔c
Positive rheumatoid factor is generally associated with:
a. Anemia
b. Hyperglobulinemia
c. Azotemia
d. Decreased ESR - Answer✔b
Rheumatoid factors are defined as:
, ©Jason MacConnell 2025 ALL RIGHTS RESERVED.
a. Antigens found in patients with RA
b. Autoantibodies with specificity for the Fc portion of the immunoglobulin (IgG) molecule
c. Antibodies that bind to circulating IgM antibodies
d. Are identical to the rheumatoid arthritis precipitin - Answer✔b
High titers of antimicrosomal antibodies are most often found in :
a. Rheumatoid arthritis
b. SLE
c. Hepatitis
d. Thyroid disease - Answer✔d
If an acute serum titer was 1:4 and the convalescent titer was 1:32, what is the best
interpretation?
a. The test should be repeated
b. The results are inconclusive since the titer went up instead of down
c. The patient had a previous infection
d. The patient has an active infection - Answer✔d
What is the labeled antibody in the indirect immunofluorescence method of antibody detection?
a. Complement
b. Anti-human immunoglobulin
c. Rheumatoid factor
d. Human anti-goat immunoglobulin - Answer✔d
A substrate is first exposed to a patient's serum, then after washing, anti-human immunoglobulin
labeled with a fluorochrome is added. What is this procedure called?
a. Fluorescence inhibition
b. Direct fluorescence
c. Indirect fluorescence
d. Fluorescent quenching - Answer✔c
What is Avidity?
a. Degree of hemolysis
b. Titer of an antigen
c. Dilution of an antibody
