GASTROINTESTINAL
PHARMACOLOGY
Yaschilal Muche
YASCHILAL MUCHE 1
,Common GIT disorders include;
• Gastro-eosophageal reflux disease (GERD)
• Peptic Ulcer Diseases (PUD)
• Vomiting
• Diarrhea
• Constipation
• Inflammatory bowel disease (IBD)
YASCHILAL MUCHE 1
,Drugs for PUD and GERD (ACID-PEPTIC
DISEASES)
YASCHILAL MUCHE 3
, Peptic Ulcer Disease (PUD)
• PUD- characterized by ulcer formation in the
esophagus, stomach, or duodenum areas of the GI
mucosa that are exposed to gastric acid and pepsin
• PUD can be;
Gastric
Duodenal
• Causes;
Stress
Drugs (NSAIDs)
H. pylori
• Pathophysiology;
Imbalance between cell destructive and cell protective
effects YASCHILAL MUCHE 4
PHARMACOLOGY
Yaschilal Muche
YASCHILAL MUCHE 1
,Common GIT disorders include;
• Gastro-eosophageal reflux disease (GERD)
• Peptic Ulcer Diseases (PUD)
• Vomiting
• Diarrhea
• Constipation
• Inflammatory bowel disease (IBD)
YASCHILAL MUCHE 1
,Drugs for PUD and GERD (ACID-PEPTIC
DISEASES)
YASCHILAL MUCHE 3
, Peptic Ulcer Disease (PUD)
• PUD- characterized by ulcer formation in the
esophagus, stomach, or duodenum areas of the GI
mucosa that are exposed to gastric acid and pepsin
• PUD can be;
Gastric
Duodenal
• Causes;
Stress
Drugs (NSAIDs)
H. pylori
• Pathophysiology;
Imbalance between cell destructive and cell protective
effects YASCHILAL MUCHE 4