exam questions with solutions
Main benefit of neoadjuvant chemotherapy (breast cancer
patient) - Ans>> Neoadjuvant therapy does not increase
survival when compared to adjuvant therapy. It only
changes the timing of treatment and can change surgical
options if the tumor is shrunk enough. If this occurs, the
patient may only require a lumpectomy plus radiation
therapy instead of needing a mastectomy
Due to Mrs. Turner's age and comorbidities, her
oncologist performs a comprehensive geriatric
assessment. You know that this assessment covers all but
which of the following: - Ans>> A comprehensive
geriatric assessment (CGA) is a multidisciplinary
evaluation to assess life expectancy and risk of morbidity
and mortality in the older patient. This assessment tool
would evaluate and include the following areas:
,functional status, socioeconomic issues, psychosocial
distress, comorbidities, cognitive function, nutritional
status, polypharmacy, and a medication review (NCCN
Older Adult Oncology Guidelines, version 1.2015).
The NCCN Older Adult Oncology Guidelines (version
1.2015) provides information on what is included in a
comprehensive geriatric assessment. Currently, more
than 60% of cancers in the United States occur in people
age ______and older and as the oncology world ages,
nearly half (46%) of cancer survivors are 70 years of age
or older - Ans>> 65
What is your best explanation for why Mrs. Turner was
given a port to receive her chemotherapy? - Ans>> Two
of the agents (docetaxel and carboplatin) that Mrs. Turner
will receive are categorized as irritants. Docetaxel can
cause a significant reaction if it extravasates. It can lead
to edema, erythema, occasional pain and blister
formation (ONS Chemo/Bio guidelines, 2014). That is the
most likely reason that Mrs. Turner was given a port for
her treatments. Some patients will receive their
treatments through a peripheral IV without incident. Just
because they are intravenous agents does not mean that
a port is required and needing a port has nothing to do
with her being older in age. Since none of these agents
are vesicants, they likely could have been given safely via
peripheral route but having a port placed is OK as well.
, Extravasation Tx: Anthracyclines --- Daunorubicin,
doxorubicin, epirubicin,
idarubicin - Ans>> Totect
Apply ice pack (remove 15
minutes prior to Totect
treatment).
Infusion should be initiated within six hours of
extravasation.
Infused over 1-2 hours for three days in an area other
than the extravasation site
The dose recommended is based on the patients' body
surface area.
• Day 1: 1,000 mg/m2
• Day 2: 1,000 mg/m2
• Day 3: 500 mg/m
Extravasation Tx: Plant alkaloid Vinblastine, vincristine,
vindesine,
vinorelbine - Ans>> Hyaluronidase