PCEUT PRACTICE FINAL EXAM QUESTIONS
WITH COMPLETE SOLUTIONS!!
Why fluid? Answer - - replace losses and correct electrolytes
- basic nutrition
- vehicle
A liquid drug preparation where the drug substance is dissolved or dispersed in
an emulsion medium Answer - injectable emulsion
A suspension of droplets of one liquid in another (usually oil and water)
Answer - emulsion
Absorption rate for lipophilic small drug molecules is generally in the order of
what? Answer - deltoid > vastus lateralis >> gluteus maximus
Absorption rate in premature newborns may be erratic due in part to what?
Answer - insufficient muscle tone and vascularity of muscle tissue
SC injection sites are readily self-administered by who? Answer - patient
SC injection sites have a risk of what present? Answer - infection
SC injection sites have a large number of what? Answer - potential injection
areas
,Systemic bioavailability for a given drug may be what? Answer - 100% or <
100%
Absorption rate may be influenced by what? Answer - massage, exercise, and
heat
What can have respiratory depression via systemic absorption and
redistribution to supra-spinal sites (brain)? Answer - opiod
At high doses, what can cause respiratory depression hours after the
administration of morphine as it spreads rostrally via the CSF? Answer - opioid
What products are usually prolonged-release medications? Answer - buccal
administration
Formulate as patches or very adhesive tablets Answer - buccal administration
Active ingredient is rapidly absorbed preventing swallowing losses Answer -
sublingual tablets
Application to skin that is intended to remove stratum corneum Answer -
keratolytic agent
What was CFC prior to 2007 (ban for environmental reasons); now HFA
(hydrofluoroalkane) ? Answer - propellant
What percent of patients had failure to coordinate MDI accuation with
inhalation? Answer - 27%
, An interval of at least 2 to 5 min between ophthalmic dosing appears to be
required for effective absorption due to volume effects. This argues for what?
Answer - combination ophthalmic product, where possible
Required dose in small drop volume Answer - adequate drug solubiltiy
Avoid lacrimation response, optimize absorption Answer - optimization of pH
Minimize irritation Answer - osmolarity
Improved stability and comfort Answer - buffered
Multidose formulations Answer - preservative effectiveness
Prolong contact of the solutions with the eye Answer - can contain viscosity
agents
Should never be compounded extemporaneously unless they can be made
sterile, including the use of sterile containeres Answer - sterile
True or False | Enteric coated aspirin tablet, rather than chewable aspirin
tablet, is the preferred dosage form to be used to a patient when a heart attack
is suspected Answer - false
True or False | All tablets can be cut without losing their integrity and potency
Answer - false
WITH COMPLETE SOLUTIONS!!
Why fluid? Answer - - replace losses and correct electrolytes
- basic nutrition
- vehicle
A liquid drug preparation where the drug substance is dissolved or dispersed in
an emulsion medium Answer - injectable emulsion
A suspension of droplets of one liquid in another (usually oil and water)
Answer - emulsion
Absorption rate for lipophilic small drug molecules is generally in the order of
what? Answer - deltoid > vastus lateralis >> gluteus maximus
Absorption rate in premature newborns may be erratic due in part to what?
Answer - insufficient muscle tone and vascularity of muscle tissue
SC injection sites are readily self-administered by who? Answer - patient
SC injection sites have a risk of what present? Answer - infection
SC injection sites have a large number of what? Answer - potential injection
areas
,Systemic bioavailability for a given drug may be what? Answer - 100% or <
100%
Absorption rate may be influenced by what? Answer - massage, exercise, and
heat
What can have respiratory depression via systemic absorption and
redistribution to supra-spinal sites (brain)? Answer - opiod
At high doses, what can cause respiratory depression hours after the
administration of morphine as it spreads rostrally via the CSF? Answer - opioid
What products are usually prolonged-release medications? Answer - buccal
administration
Formulate as patches or very adhesive tablets Answer - buccal administration
Active ingredient is rapidly absorbed preventing swallowing losses Answer -
sublingual tablets
Application to skin that is intended to remove stratum corneum Answer -
keratolytic agent
What was CFC prior to 2007 (ban for environmental reasons); now HFA
(hydrofluoroalkane) ? Answer - propellant
What percent of patients had failure to coordinate MDI accuation with
inhalation? Answer - 27%
, An interval of at least 2 to 5 min between ophthalmic dosing appears to be
required for effective absorption due to volume effects. This argues for what?
Answer - combination ophthalmic product, where possible
Required dose in small drop volume Answer - adequate drug solubiltiy
Avoid lacrimation response, optimize absorption Answer - optimization of pH
Minimize irritation Answer - osmolarity
Improved stability and comfort Answer - buffered
Multidose formulations Answer - preservative effectiveness
Prolong contact of the solutions with the eye Answer - can contain viscosity
agents
Should never be compounded extemporaneously unless they can be made
sterile, including the use of sterile containeres Answer - sterile
True or False | Enteric coated aspirin tablet, rather than chewable aspirin
tablet, is the preferred dosage form to be used to a patient when a heart attack
is suspected Answer - false
True or False | All tablets can be cut without losing their integrity and potency
Answer - false
