BOC HEMATOLOGY Exam Questions with Revised
Answers| Verified 100% Correct
What lab test isn't used to distinguish CML from PV? - ✔✔hypercellular bone marrow
What describes a beta thalassemia genotype b+/b? - ✔✔beta thalassemia minor
Name a disease not associated with a dysfunction of PMNs. - ✔✔Gaucher's disease
What is not an important protein regulator of Fe metabolism? - ✔✔hemosiderin
Which test is not abnormal with Stuart-Prower Factor deficiency? - ✔✔fibrinogen
If a patient's WBC is 50,000/mm3, what test should be ordered to determine if this is a
leukemoid rxn or a chronic myelocytic leukemia? - ✔✔leukocyte alkaline
phosphatase stain
After several incidneces of deep vein thrombosis, a patient is assessed for
hypercoagulability. What would an appropriate panel for hypercoaglability screening? -
✔✔PT, aPTT, LA screeing, APC, d-dimer screening
You are running QC for HA1C by HPLC. The high control was 2.5 SD above the mean. The
low control was 2.2 SD below the mean. Should you continue to run patient samples? -
✔✔no, QC values indicate a violation of the R4S rule and should be rejected
What is the normal cellularity of an iliac crest bone marrow biopsy in a 50-year old
male? - ✔✔50%
,The appropriate magnification for a manual RBC cell count using a hemocytometer is
what? - ✔✔40X (dry)
After briefly circulating in the peripheral blood, what cell becomes a tissue macrophage
whose main function is phagocytosis? - ✔✔monocyte
Which of the following is considered one of the most common coagulation inhibitors? -
✔✔lupus anticoagulant
To determine if an elevated aPTT is caused by a factor deficiency or a factor inhibitor
when the PT is normal, the 1st step would be? - ✔✔mix one part patient plasma and
one part normal pooled plasma and repeat the aPTT
Abnormal platelet function seen in patients with Bernard-Soulier Syndrome is caused by
which of the following platelet components? - ✔✔defective glycoprotein ib/IX
Hemophilia B or Christmas disease is the result of a hereditary deficiency in which
coagulation factor? - ✔✔factor IX
Following stain rxns were resulted on a suspected case of leaukemia:
Myeloperoxidase: +
Sudan Black B: +
Chloroacetate Esterase: +
Nonspecific Esterase: - - ✔✔acute myelocytic leukemia
What genetic description will not contain Bart's hemoglobin at birth? -
✔✔heterozyhous alpha thalassemia-2
, What factor may be deficient if both the PT and aPTT are prolonged? - ✔✔factor II
What test results might be consistent for a patient with the following findings:
macrocytosis, anemia, leukopenia, and thrombocytopenia? - ✔✔MCV 115 fL
Hgb 7.5 g/dL
WBC 2.5x10 3/uL
Platelets 75,000/uL
Patient with a history of mucocutaneous bleeding:
PT 12 sec
APTT 26 sec
BT 18 min
ADP abnormal
Thrombin abnormal
Collagen abonormal
Ristocetin normal - ✔✔glanzmann thromasthenia
The nucleus of a small lymphocyte is about the same size as a: - ✔✔normal
erythrocyte
Alder-Reilly inclusions may be found in which cell types? - ✔✔all types of mature
white blood cells
A semen sample for analysis should generally be received at the testing site within what
period of time? - ✔✔1 hr
Answers| Verified 100% Correct
What lab test isn't used to distinguish CML from PV? - ✔✔hypercellular bone marrow
What describes a beta thalassemia genotype b+/b? - ✔✔beta thalassemia minor
Name a disease not associated with a dysfunction of PMNs. - ✔✔Gaucher's disease
What is not an important protein regulator of Fe metabolism? - ✔✔hemosiderin
Which test is not abnormal with Stuart-Prower Factor deficiency? - ✔✔fibrinogen
If a patient's WBC is 50,000/mm3, what test should be ordered to determine if this is a
leukemoid rxn or a chronic myelocytic leukemia? - ✔✔leukocyte alkaline
phosphatase stain
After several incidneces of deep vein thrombosis, a patient is assessed for
hypercoagulability. What would an appropriate panel for hypercoaglability screening? -
✔✔PT, aPTT, LA screeing, APC, d-dimer screening
You are running QC for HA1C by HPLC. The high control was 2.5 SD above the mean. The
low control was 2.2 SD below the mean. Should you continue to run patient samples? -
✔✔no, QC values indicate a violation of the R4S rule and should be rejected
What is the normal cellularity of an iliac crest bone marrow biopsy in a 50-year old
male? - ✔✔50%
,The appropriate magnification for a manual RBC cell count using a hemocytometer is
what? - ✔✔40X (dry)
After briefly circulating in the peripheral blood, what cell becomes a tissue macrophage
whose main function is phagocytosis? - ✔✔monocyte
Which of the following is considered one of the most common coagulation inhibitors? -
✔✔lupus anticoagulant
To determine if an elevated aPTT is caused by a factor deficiency or a factor inhibitor
when the PT is normal, the 1st step would be? - ✔✔mix one part patient plasma and
one part normal pooled plasma and repeat the aPTT
Abnormal platelet function seen in patients with Bernard-Soulier Syndrome is caused by
which of the following platelet components? - ✔✔defective glycoprotein ib/IX
Hemophilia B or Christmas disease is the result of a hereditary deficiency in which
coagulation factor? - ✔✔factor IX
Following stain rxns were resulted on a suspected case of leaukemia:
Myeloperoxidase: +
Sudan Black B: +
Chloroacetate Esterase: +
Nonspecific Esterase: - - ✔✔acute myelocytic leukemia
What genetic description will not contain Bart's hemoglobin at birth? -
✔✔heterozyhous alpha thalassemia-2
, What factor may be deficient if both the PT and aPTT are prolonged? - ✔✔factor II
What test results might be consistent for a patient with the following findings:
macrocytosis, anemia, leukopenia, and thrombocytopenia? - ✔✔MCV 115 fL
Hgb 7.5 g/dL
WBC 2.5x10 3/uL
Platelets 75,000/uL
Patient with a history of mucocutaneous bleeding:
PT 12 sec
APTT 26 sec
BT 18 min
ADP abnormal
Thrombin abnormal
Collagen abonormal
Ristocetin normal - ✔✔glanzmann thromasthenia
The nucleus of a small lymphocyte is about the same size as a: - ✔✔normal
erythrocyte
Alder-Reilly inclusions may be found in which cell types? - ✔✔all types of mature
white blood cells
A semen sample for analysis should generally be received at the testing site within what
period of time? - ✔✔1 hr