BOC HEMATOLOGY Exam Questions with Revised
Answers| Verified 100% Correct
An enzyme deficiency associated with a moderate to severe hemolytic anemia after the
patient is exposed to certain drugs and characterized by red cell inclusions formed by
denatured hemoglobin is:
a. lactacte dehydrogenase deficiency
b. G-6-PD deficiency
c. pyruvate kinase deficiency
d. hexokinase deficiency - ✔✔b. G-6-PD deficiency
Patients with A(-) type G-6-PD deficiency are least likely to have hemolytic episodes in
which of the following situations?
a. following the administration of oxidizing drugs
b. following the ingestion of fava beans
c. during infections
d. spontaneously - ✔✔d. spontaneously
A 50yo patient was found to have the following lab results:
Hgb: 7.0g/dL
Hct: 20%
RBC 2.0x10^6/uL
It was determined that the patient was suffering from pernicious anemia. Which of the
following sets of results most likely was obtained from the same patient?
WBCs Platelets Reticulocytes
Result A 17,500 350,000 5.2%
,Result B 7,500 80,000 4.1%
Result C 5,000 425,000 2.9%
Result D 3,500 80,000 0.8% - ✔✔d. WBCs 3500, Platelets 80000, reticulocytes 0.8%
-Pancytopenia and normal reticulocytes: see low cell production
Megaloblastic asynchronous development in the bone marrow indicates which one of
the following?
a. proliferation of erythrocyte precursors
b. impaired synthesis of DNA
c. inadequate production of erythropoitein
d. deficiency of G-6-PD - ✔✔b. impaired synthesis of DNA
A characteristic morphologic feature in hemoglobin C disease is:
a. macrocytosis
b. spherocytosis
c. rouleaux formation
d. target cells - ✔✔d. target cells
A patient had the following blood values:
RBC: 6.5x10^6
Hgb: 13.0g/dL
Hct: 39.0%
MCV: 65um^3
MCH: 21.5pg
MCHC: 33%
These results are compatible with:
,a. iron deficiency
b. pregnancy
c. thalassemia major
d. beta thalassemia major - ✔✔c. thalassemia major
Lab findings in hereditary spherocytosis do not include:
a. decreased osmotic fragility
b. increased autohemolysis corrected by glucose
c. reticulocytosis
d. shortened reythrocyte survival - ✔✔a. decreased osmotic fragility
Which of the following types of polycythemia is a severely burned patient most likely to
have?
a. polycythemia vera
b. polycythemia, secondary to hypoxia
c. relative polycythemia associate with dehydration
d. polycythemia associated with renal disease - ✔✔c. relative polycythemia associate
with dehydration
A 40yo man had an erythrocyte count of 2.5x10^6/uL, hematocrit of 22% and a
reticulocyte count of 2.0%. Which of the following statements best describes his
condition?
a. the absolute retic count is 50x10^3/uL, indicating that the bone marrow is not
adequately compensating for the anemia - ✔✔a
-Absolute reticulocyte count
RBC count (x10^12/L) * retic%
, A wright-stained peripheral smear reveals the following:
Erythrocytes enlarged 1.5x to 2x normal size
Schuffner dots
Parasites with irregular "spread out" torphozoites, golden-brown pigment
12-24 merozoites
Wide range of stages
This is consistent with Plasmodium:
a. falciparum
b. malariae
c. ovale
d. vivax - ✔✔d. vivax
-Malaria parasites
The mean value of a reticulocyte count on specimens of cord blood from healthy, full-
term newborn is approximately:
a. 0.5%
b. 2.0%
c. 5.0%
d. 8.0% - ✔✔c. 5.0%
The following results were obtained on a patient's blood:
Hgb: 11.5g/dL
Hct: 40%
MCV: 89um^3
MCH: 26pg
MCHC: 29%
Answers| Verified 100% Correct
An enzyme deficiency associated with a moderate to severe hemolytic anemia after the
patient is exposed to certain drugs and characterized by red cell inclusions formed by
denatured hemoglobin is:
a. lactacte dehydrogenase deficiency
b. G-6-PD deficiency
c. pyruvate kinase deficiency
d. hexokinase deficiency - ✔✔b. G-6-PD deficiency
Patients with A(-) type G-6-PD deficiency are least likely to have hemolytic episodes in
which of the following situations?
a. following the administration of oxidizing drugs
b. following the ingestion of fava beans
c. during infections
d. spontaneously - ✔✔d. spontaneously
A 50yo patient was found to have the following lab results:
Hgb: 7.0g/dL
Hct: 20%
RBC 2.0x10^6/uL
It was determined that the patient was suffering from pernicious anemia. Which of the
following sets of results most likely was obtained from the same patient?
WBCs Platelets Reticulocytes
Result A 17,500 350,000 5.2%
,Result B 7,500 80,000 4.1%
Result C 5,000 425,000 2.9%
Result D 3,500 80,000 0.8% - ✔✔d. WBCs 3500, Platelets 80000, reticulocytes 0.8%
-Pancytopenia and normal reticulocytes: see low cell production
Megaloblastic asynchronous development in the bone marrow indicates which one of
the following?
a. proliferation of erythrocyte precursors
b. impaired synthesis of DNA
c. inadequate production of erythropoitein
d. deficiency of G-6-PD - ✔✔b. impaired synthesis of DNA
A characteristic morphologic feature in hemoglobin C disease is:
a. macrocytosis
b. spherocytosis
c. rouleaux formation
d. target cells - ✔✔d. target cells
A patient had the following blood values:
RBC: 6.5x10^6
Hgb: 13.0g/dL
Hct: 39.0%
MCV: 65um^3
MCH: 21.5pg
MCHC: 33%
These results are compatible with:
,a. iron deficiency
b. pregnancy
c. thalassemia major
d. beta thalassemia major - ✔✔c. thalassemia major
Lab findings in hereditary spherocytosis do not include:
a. decreased osmotic fragility
b. increased autohemolysis corrected by glucose
c. reticulocytosis
d. shortened reythrocyte survival - ✔✔a. decreased osmotic fragility
Which of the following types of polycythemia is a severely burned patient most likely to
have?
a. polycythemia vera
b. polycythemia, secondary to hypoxia
c. relative polycythemia associate with dehydration
d. polycythemia associated with renal disease - ✔✔c. relative polycythemia associate
with dehydration
A 40yo man had an erythrocyte count of 2.5x10^6/uL, hematocrit of 22% and a
reticulocyte count of 2.0%. Which of the following statements best describes his
condition?
a. the absolute retic count is 50x10^3/uL, indicating that the bone marrow is not
adequately compensating for the anemia - ✔✔a
-Absolute reticulocyte count
RBC count (x10^12/L) * retic%
, A wright-stained peripheral smear reveals the following:
Erythrocytes enlarged 1.5x to 2x normal size
Schuffner dots
Parasites with irregular "spread out" torphozoites, golden-brown pigment
12-24 merozoites
Wide range of stages
This is consistent with Plasmodium:
a. falciparum
b. malariae
c. ovale
d. vivax - ✔✔d. vivax
-Malaria parasites
The mean value of a reticulocyte count on specimens of cord blood from healthy, full-
term newborn is approximately:
a. 0.5%
b. 2.0%
c. 5.0%
d. 8.0% - ✔✔c. 5.0%
The following results were obtained on a patient's blood:
Hgb: 11.5g/dL
Hct: 40%
MCV: 89um^3
MCH: 26pg
MCHC: 29%
