TEST BANK FOR Evolutionary Analysis 5th Edition b
m m m m m m m
y Herron Jon; Freeman Scott ISBN 9780321998378 Ch
m m m m m m m
apter 1-20 A+
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Chapterm1mmAmCasemformEvolutionarymThinking:mUnderstandingmHIV
1) InmwhichmofmthemfollowingmregionsmhasmAIDSmkilledmthemlargestmnumbermofmindividuals?
A) India
B) Sub-SaharanmAfrica
C) UnitedmStates
D) China
E) UnitedmKingdommAnswer:mBmSection:m1.1
Skill:mKnowledge/Comprehension
2) ThemHIVmvirusmcontainsmallmofmthemfollowingmcomponentsmexceptm .
A) integrase
B) double-strandedmRNA
C) single-strandedmRNA
D) reversemtranscriptase
E) proteasemAnswer:mBmSection:m1.1
Skill:mKnowledge/Comprehension
3) ThemacronymmHIVmstandsmformwhichmofmthemfollowing?
A) humanmintercellularmvirus
B) humanmimmunemvirus
C) humanmimmunodeficiencymvirus
D) humanmimmunitymvirus
E) humanmimmunodeficiencymvectormAnswer:mC
Section:m1.1
Skill:mKnowledge/Comprehension
4) WhichmofmthemfollowingmenzymesmismresponsiblemformtranscribingmviralmRNAmintomDNA?
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,CreatedmBy:mAmSolution
A) RNAmpolymerase
B) reversemtranscriptase
C) DNAmpolymerase
D) reversemintegrase
E) RNAmduplicasemAnswer:mBmSection:m1.1
Skill:mKnowledge/Comprehension
m
5)
ThemproteinsmthatmenablemthemHIVmvirusmtombindmtomcellsmaremtypicallymCD4mandmCCR5.mO
nmwhatmtypemofmcellsmaremthesemproteinsmtypicallymobserved?
A) plasmamcells
B) dendriticmcells
C) effectormhelpermTmcells
D) memorymhelpermTmcells
E) bothmCmandmDmAnswer:mEmSection:m1.1
Skill:mKnowledge/Comprehension
6)
ThemAIDSmphasemofmHIVminfectionmbeginsmwhenmthemconcentrationmofmCD4mTmcellsminmthe
m bloodmdropsmbelowmwhatmconcentration?
A) 2,000mcellsmpermcubicmmillimeter
B) 1,000mcellsmpermcubicmmillimeter
C) 500mcellsmpermcubicmmillimeter
D) 200mcellsmpermcubicmmillimeter
E) NomCD4mTmcellsmaremobserved.mAnswer:mD
Section:m1.1
Skill:mKnowledge/Comprehension
7) WhichmofmthemfollowingmdrugmcategoriesmaremusedmtomtreatmHIVminfections?
A) integraseminhibitors
B) proteaseminhibitors
C) reversemtranscriptaseminhibitors
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,CreatedmBy:mAmSolution
D) DNAseminhibitors
E) fusionminhibitorsmAnswer:mDmSection:m1.2
Skill:mKnowledge/Comprehension
8) CoreceptorminhibitorsmblockmHIVminfectionmbympreventingmwhichmofmthemfollowing?
A) bindingmofmthemHIVmvirionmontomthemplasmammembrane
B) bindingmofmthemHIVmvirionmontomthemCCR5mreceptor
C) bindingmofmthemHIVmvirionmontomthemgp120mprotein
D) degradingmthemcoreceptormsomthemvirionmcannotmattach
E) bindingmofmthemHIVmvirionmontomthemCD4mreceptormAnswer:mB
Section:m1.2
Skill:mApplication/Analysis
9) Whatmismthemeffectmofmthem∆32mallelemofmCCR5monmHIVmbinding?
A)
appearsmonmthemsurfacemofmCD4mTmcells,mbutmthemHIVmvirionmismunablemtominfectmthemhostmc
ell
B) doesmnotmappearmonmthemsurfacemofmCD4mTmcells
C) appearsmonmthemsurfacemofmthemCD4mTmcellsmandminactivatesmthemvirionmuponmbinding
D) interferesmwithmbindingmofmthemvirionmtomthemCD4mreceptormprotein
m
E)
appearsmonmthemsurfacemofmthemCD4mTmcellsmandmcausesmthemvirionmtomlysemuponmbindingmA
nswer:mB
Section:m1.3
Skill:mApplication/Analysis
10)
Them∆32mallelemofmCCR5mismfoundmatmthemhighestmfrequencyminmwhichmofmthemfollowingmpo
pulations?
A) Africans
B) Japanese
C) NorthmAmericans
D) Europeans
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, CreatedmBy:mAmSolution
E) SouthmAmericansmAnswer:mDmSection:m1.3
Skill:mKnowledge/Comprehension
11) HIV-
1mismbelievedmtomhavembeenmtransmittedmtomhumansmfrommwhichmofmthemfollowingmorganisms?
A) gorillas
B) sootymmangabeys
C) Africanmgreenmmonkeys
D) chimpanzees
E) baboonsmAnswer:mDmSection:m1.4
Skill:mKnowledge/Comprehension
12) HIV-
1mGroupmMmismresponsiblemform95%mofmhumanminfections.mWhenmismitmestimatedmthatmHIV-
1mGroupmMmwasmtransferredmtomhumans?
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer:mCmSection:m1.4
Skill:mKnowledge/Comprehension
13) AntibodiesmandmkillermTmcellsmrecognizemHIVmormHIV-
infectedmcellsmbymbindingmtomshortmpiecesmofmviralmproteinsmdisplayedmonmthemvirusmormtheminfected
m hostmcell.mThesemshortmpiecesmofmviralmproteinsmaremcalledm .
A) coatmproteins
B) virosomes
C) proteosomes
D) epitopes
E) episomesmAnswer:mD
m
Section:m1.5
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