s s s s s s s
n Safety, 2nd Edition,Workman & LaCharity 100% A+ GRADED( ALL CH
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APTERS COVERED) s
Chapters01:sDrugsRegulation,sActions,sandsResponses
Workmans&sLaCharity:sUnderstandingsPharmacology:sEssentialssforsMedicationsSafety,s2ndsEditi
on
MULTIPLEsCHOICEsB
ASICsCONCEPTS
1. Whichshealthscaresprofessionalshassthesmajorsresponsibilitysforsdispensingsprescribedsdr
ugssundersthesdirectionsofsaspharmacist?
a. Physician
b Nursespractitioner
.
c. Licensedsnurse
d Pharmacystechnician
.
ANS:s D
Thesphysiciansandsnursespractitionershavesthesmajorsresponsibilitysforsprescribingsdrugs,snotsdispen
singsthem.sTheslicensedsnurseshassthesprimarysresponsibilitysforsadministeringsdrugs,salthoughsund
erssomescircumstancessaslicensedsnursesmaysdispensesprescribedsdrugssbutsthississnotshissorshersmajo
rsresponsibilitysinsdrugstherapy.sThespharmacystechnicianshassthesmajorsresponsibilitysofsdispensin
gsprescribedsdrugssundersthesdirectionsofsaslicensedspharmacist.
DIF: CognitivesLevel:sRemembering REF: p.s3
2. Whichstermsdescribesstheseffectsofsasdrugsthatsimprovessbodysfunction?
a. Sideseffect
b Intendedsaction
.
c. Adversesreaction
d Idiosyncraticsresponse
.
ANS:s B
Thespurposesofsdrugstherapysisstostakesasdrugstosprevent,sreduce,sorscorrectsashealthsproblem.sThi
ssresponsesissanysdrug’ssintendedsactionsalsosknownsassastherapeuticsresponse.
DIF: CognitivesLevel:sRemembering REF: p.s3
3. Whichstypesofsdrugsnamesiss“owned”sbysthescompanysthatsmanufacturessit?
a. Genericsname
b Chemicalsname
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s s s s s s s s s s
APTERS COVERED) s
.
c. Categorysname
d Tradesname
.
ANS:s D
Theschemicalsnamesissasdrug’ssexactschemicalscomposition.sThesgenericsnamesissthesnamesassigneds
tosthesdrugsbysthesU.S.sAdoptedsNamessCouncilsandsissnotsownedsbysanyone.sThescategorysnamesref
ersstosthestypesofsdrugs(whatsitsdoessorswhatsitsissusedsfor)sandsissnotsansactualsdrugsname.sThestradesna
mes(brandsname)sissthesnamesprovidedsandsownedsbysasspecificsdrug’ssmanufacturer.
DIF: CognitivesLevel:sRemembering REF: p.s4
4. Whichsdrugsorsdrugsclasssissas“highsalert”sdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:s B
Ashighsalertsdrugsissonesinswhichsharmsisslikelystosresultsifsgivensatstheswrongsdose,stostheswrongspatie
nt,sorsnotsgivenstosthescorrectspatient.sDrugssclassifiedsasshighsalertsdrugssincludespotassium,snarcotic
ss(opioids),sinsulin,scancerschemotherapysdrugs,sandsheparins(orsanysdrugsthatsstronglysaffectssblood
sclotting).sPenicillin,sNSAIDs,sandscalciumsaresnotsconsideredshighsalertsdrugs.
DIF: CognitivesLevel:sRemembering REF: p.s4
5. Whatsissthestermsforsasdrugsthatshassthessamesactionsassasnaturallysoccurringsbodyshor
monesorsenzyme?
a. Agonist
b Blockingsagent
.
c. Chemical
d Duplicator
.
ANS:s A
Asdrugsagonistsissansextrinsicsdrugsthatsactivatessthesreceptorssitessofsascellsandsmimicssthesacti
onssofsnaturallysoccurringsbodyssubstancess(intrinsicsdrugs).sAsblockingsagentsissasdrug
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s s s s s s s s s s
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antagonist.sAschemicalswouldsnotsnecessarilysbesasdrugsatsall.sAsduplicatorsissnotsaspharmacologicster
m.
DIF: CognitivesLevel:sRemembering REF: pp.s6-7
6. Whichstermsdescribesshowsthesbodysaffectssdrugsactivity?
a. Drugspotency
b Pharmacodynamics
.
c. Therapeuticseffect
d Pharmacokinetics
.
ANS:s D
Thestermspharmacokineticssrefersstosdrugsmetabolismsandshowsthesbodyschangessasdrug.sPharmacody
namicssrefersstoshowsasdrugsworksstoschangesbodysfunction.sDrugspotencysrefersstoshowsstronglysorstos
whatsdegreesasdrugsexertssitsseffects.sThestherapeuticseffectsisscloserstospharmacodynamics,smeanings
howsasdrugsworksstoschangesbodysfunction.
DIF: CognitivesLevel:sRemembering REF: p.s10
7. InsthesUnitedsStates,swhichsgroupsissresponsiblesforsenforcingsestablishedsstandardssforsdr
ugsmanufacturing?
a. U.S.sPharmacopeia
b NationalsInstitutessofsHealth
.
c. FoodsandsDrugsAdministration
d AssociationsofsPharmaceuticalsManufacturers
.
ANS:s C
ThesstandardssforsdrugsmanufacturesaresestablishedsbysthesU.S.sPharmacopeia.sThesesstandardssares
enforcedsbysthesFoodsandsDrugsAdministration.sNeithersthesNationalsInstitutessofsHealthsnorsthesAss
ociationsofsPharmaceuticalsManufacturersshassanysauthoritystosenforcesdrugsstandards.
DIF: CognitivesLevel:sRemembering REF: p.s5
8. Whichsfactorsissasmajorsdisadvantagesofsthestransdermalsdrugsdeliverysroute?
a. Onlysasprescriberscansadministersdrugssbysthestransdermalsroute.
b Transdermalsdrugssmustsbessterilesrathersthansclean.
.
c. Firstspasssdrugslosssbysthissroutesissthesmostsextensive.
d Drugsabsorptionsissdependentsonsadequatescirculation.
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s s s s s s s s s s
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.
ANS:s D
Oncesastransdermalsdrugsmovessthroughsthesskin,sitsmustsentersthesbloodstreamstosreachsitsstargetstiss
ue.sIfscirculationsisspoorstosthesareaswheresthestransdermalsdrugsissapplied,sveryslittle,sifsany,sofsthesdr
ugswillsreachsitsstargetstissue.
DIF: CognitivesLevel:sRemembering REF: p.s12
9. Howsaresintrinsicsdrugssdifferentsfromsextrinsicsdrugs?
a.Intrinsicsdrugssaresmadesbysthesbody,swhereassextrinsicsdrugssaresmadesoutsidesthesbody.
b Intrinsicsdrugssaresadministeredsbysthesparenteralsroute,swhereassextrinsicsdrugssare
. administeredsbysthesoralsroute.
c.Extrinsicsdrugsscansonlysbesappliedstosthesskinsorsmucoussmembranes,swhereassintrinsicsdr
ugssarestakensinternally.
d Extrinsicsdrugssrequiresasprescriptionsforsadministration,swhereassintrinsicsdrugssare
. availablesover-the-counter.
ANS:s A
Intrinsicsdrugssarestheshormones,senzymes,sandsotherschemicalssmadesbysthesbodysthatschangescellsa
ctivity.sExtrinsicsdrugssaresmanufacturedsfromschemical,sanimal,sorsplantssourcessandsmustshavesasm
eanssofsenteringsthesbodysinsorderstoschangescellsactivity.
DIF: CognitivesLevel:sUnderstanding REF: p.s3
10. Aspatientsasksswhyshissdrugstoscontrolshighsbloodspressureshassonlysonesgenericsnamesandstwo
sdifferentstradesnames.sWhatsissyoursbestsresponse?
a. “Mostsdrugsshavesdifferentstradesnamessthatsindicatesdifferentsdosages.”
b “Thestwosdifferentstradesnamessindicatesthatsonesissasmorespuresandssafersdrugsthansthesother.”
.
c. “Thesgenericsnamesissthesactualsofficialsdrugsnamesandsthestradesnamesissasbrandsownedsby
asspecificsmanufacturer.”
d “Ifsyoushavesinsurance,syouscansgetsthestradesnamesdrug,swhichsissusuallysmoresexpensivesthanst
. hesgenericsnamedsdrug.”
ANS:s C
ThesgenericsnamesissthesnamesassignedstosthesdrugsbysthesU.S.sAdoptedsNamessCouncilsandsissnotso
wnedsbysanyone.sThestradesnames(brandsname)sissthesnamesprovidedsandsownedsbysasspecificsdrug’ss
manufacturer.sMoresthansonesmanufacturerscansmakesandssellsthessamesdrugsatsthessamestimesundersas
differentstradesname.sRegardlesssofstradesname,sallsdrugssthatshavesthessamesgenericsnamesmustsbesal
ikesinstheirschemicalscompositionsandsstrength.
DIF: CognitivesLevel:sApplyingsorsHigher REF: pp.s3-4