Exam LATEST REAL EXAM QUESTIONS AND
CORRECT ANSWERS (VERIFIED ANSWERS)|AGRADE
Institutional Official (IO) - Answer- Submits the Animal Welfare Assurance of
Compliance that the animal research program meets all relevant regulations and
standards
Skills required for ALATs - Answer- Feeding animals, changing animal bedding, and
determining the sex of the animals
Technician Registry - Answer- - Participation entitles you to be an RALAT
- Status must be renewed after two years
- Participation demonstrates a commitment to enhancing your knowledge and skill in
animal husbandry
RALAT - Answer- Registered Assistant Laboratory Animal Technician
Animal Welfare Act (AWA) - Answer- - Enacted by U.S. Congress in 1966 to establish
legal standards for laboratory animal care and use
- Governs the use in research of all warm-blooded vertebrates (living or dead), with
some exceptions
- Requires that minimum standards of care and treatment be provided for covered
animals bred for commercial sale, used in research, transported commercially, or
exhibited to the public
- Specifically protects employees who report significant deficits in a research program
Must be studied to prepare for the ALAT certification examination - Answer- - ALAT
Training Manual
- The Guide for the Care and Use of Laboratory Animals
Duties routinely performed by an ALAT - Answer- - Facility sanitation procedures
- Record keeping
- Animal husbandry
The Guide for the Care and Use of Laboratory Animals is composed of: - Answer- -
Animal environment and housing
- Euthanasia
- Personnel qualification
- Published by OLAW
- Requires animal facilities to follow AVMA Guidelines for the Euthanasia of Animals
Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS
Policy) - Answer- - Federal mandate that applies to ferally funded research projects
,- Enforced by the Office of Laboratory Animal Welfare (OLAW)
- Covers all live vertebrates used/intended for use in research, training, experimental
purposes, and biological testing
- Requires animal facilities to follow AVMA Guidelines for the Euthanasia of Animals
PHS Policy Coverage - Answer- All live vertebrates used or intended for use in
research, research training, experimentation, biological testing, etc.
Birds, mice, and rats bred for research
Fish, amphibians, and reptiles
Office of Laboratory Animal Welfare (OLAW) - Answer- - The agency responsible for
enforcing the PHS Policy
- Publishes The Guide for the Care and Use of Laboratory Animals
Animal use protocol - Answer- A document written by the Principal Investigator and
approved by the IACUC, that describes and justifies the use of animals for a project
Institutional Animal Care and Use Committee (IACUC) - Answer- - Responsible for
ensuring that animal care at the facility conforms to the AWR
- Responsible for ensuring that the animal research program is in compliance with
applicable laws, policies, regulations, and guidelines
- Reviews and approves the animal use protocol
- Reports to the IO or CEO, per the AWR
- Performs semi-annual inspections of the facility
- Approves all work with vertebrate animals at the institution by reviewing each animal
use protocol
Animal Welfare Regulations - Answer- - Defines the roles of the different individuals
in the animal facility (such as the attending veterinarian, the IO, and IACUC)
- Published each year in the Code of Federal Regulations
- Administered and enforced by the APHIS of the USDA
- Requires laboratory animal research facilities with covered species to register with the
USDA
- Requires an IACUC to oversee the animal care and use program and to report to the
IO or CEO
AWA Covered Species - Answer- Hamsters, guinea pigs, rabbits, cats, dogs, and
NHP's
(living or dead)
Species not covered by AWA - Answer- Mice of the genus Mus, bred for research
Rats of the genus Rattus, bred for research
Farm animals intended for use as food, fiber, or agricultural research
Horses not used in research
, Birds
Reptiles
Fish
Amphibians
Invertebrates
United States Department of Agriculture (USDA) - Answer- - Requires that animal
suppliers and research facilities maintain records of acquisition and disposal
- Receives annual reports submitted by laboratory animal facilities
- Administers the AWR
IACUC Requirements of AWR - Answer- At least 3 members, including:
- Chairperson
- Veterinarian with training/experience in lab animal medicine
- Public member
(No more than three members may be from the same administrative unit)
IACUC Requirements of the Guide - Answer- - Veterinarian with training/experience
in lab animal medicine
- Scientist using animals
- Nonscientist
- Public member
IACUC Requirements of PHS Policy - Answer- At least 5 members, including:
- Scientist using animals
- Veterinarian with training/experience, and has program authority
- Nonscientist
- Unaffiliated member
USDA and Plant Health Inspection Service (APHIS) - Answer- - Charged with
administering and enforcing AWR
- Conducts unannounced site visits at least annually to inspect the facility; inspector
looks at animals covered under AWA , reviews IACUC's semi-annual facility inspection
reports, and then issues a report that is available to the public
- Has the authority to stop the research being conducted at the facility if violations are
not corrected promptly
Freedom of Information Act (FOIA) - Answer- - 1966 federal law that allows citizens
to obtain copies of most public records
- Allows the general public to view the APHIS inspector's reports
PHS Assurance (frequency) - Answer- - Describes the institution's program for the
care and use of animals
- Submitted by the IO to OLAW
- Also called the "Animal Welfare Assurance Compliance Statement"