Test Bank for Pharmacotherapeutics for Advanced Practice Nurse Prescribers Fifth Edition by Teri Moser Woo & Marylou V. Robinson ISBN 9780803669260 Chapter 1-55 | Complete Guide A+

Pharmacotherapeutics for Advanced Practice Nurse Prescribers 5th Edition Woo Robinson Test Bank Chapter 1. The Role of the Nurse Practitioner Multiple Choice Identify the choice that best completes the statement or answers the question. 1. Nurse practitioner prescriptive authority is regulated by: 1. The National Council of State Boards of Nursing 2. The U.S. Drug Enforcement Administration 3. The State Board of Nursing for each state 4. The State Board of Pharmacy 2. The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber include: 1. Nurses know more about Pharmacology than other prescribers because they take it both in their basic nursing program and in their APRN program. 2. Nurses care for the patient from a holistic approach and include the patient in decision making regarding their care. 3. APRNs are less likely to prescribe narcotics and other controlled substances. 4. APRNs are able to prescribe independently in all states, whereas a physician’s assistant needs to have a physician supervising their practice. 3. Clinical judgment in prescribing includes: 1. Factoring in the cost to the patient of the medication prescribed 2. Always prescribing the newest medication available for the disease process 3. Handing out drug samples to poor patients 4. Prescribing all generic medications to cut costs 4. Criteria for choosing an effective drug for a disorder include: 1. Asking the patient what drug they think would work best for them 2. Consulting nationally recognized guidelines for disease management 3. Prescribing medications that are available as samples before writing a prescription 4. Following U.S. Drug Enforcement Administration guidelines for prescribing 5. Nurse practitioner practice may thrive under health-care reform because of: 1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes 2. The fact that nurse practitioners will be able to practice independently 3. The fact that nurse practitioners will have full reimbursement under health-care reform 4. The ability to shift accountability for Medicaid to the state level Chapter 1. The Role of the Nurse Practitioner Answer Section MULTIPLE CHOICE 1. ANS: 3 PTS: 1 2. ANS: 2 PTS: 1 3. ANS: 1 PTS: 1 4. ANS: 2 PTS: 1 5. ANS: 1 PTS: 1 Chapter 2. Review of Basic Principles of Pharmacology Multiple Choice Identify the choice that best completes the statement or answers the question. 1. When a patient has low levels of albumin, it is important in prescribing because: 1. Affects how drugs are distributed to target tissues. 2. The drug's solubility may not match where it needs to be absorbed. 3. Less free drug is available to produce an effect. 4. Drugs bound to albumin are easily excreted by the kidneys. 2. Drugs with a significant first-pass effect: 1. Must only be given orally. 2. Bypass the liver's circulation. 3. Are quickly metabolized by the liver with little desired effect. 4. Are converted by the liver into more active and fat-soluble forms. 3. Volatile drugs are likely excreted via the: 1. Kidneys 2. Lungs 3. Bile and feces 4. Skin 4. Medroxyprogesterone (Depo Provera) is given intramuscularly to: 1. Ensure the drug reaches its target tissue. 2. Justify the use of loading doses. 3. Extend the drug's availability and activity. 4. Target collagen tissues. 5. The dosing interval of cephalexin every 8 hours is based on its: 1. Affinity to the target receptor. 2. Biological half-life. 3. Pharmacodynamics. 4. Safety profile and side effects. 6. A loading dose of azithromycin on the first day rapidly achieves: 1. Therapeutic drug levels. 2. Requires several half-lives to attain. 3. Is affected by renal function. 4. Directly correlates with drug distribution to target tissues. 7. The point in the drug concentration curve that indicates the first therapeutic effect is: 1. Minimum adverse effect level. 2. Peak of action. 3. Onset of action. 4. Therapeutic range. 8. Phenytoin requires drawing a trough level to determine if the drug: 1. Has a wide therapeutic range. 2. Will be administered for a short time. 3. Correlates with dose and receptor saturation. 4. Is within the therapeutic range. 9. A peak drug level above the minimum toxic concentration indicates: 1. Therapeutic effects. 2. Adverse responses. 3. Need for shortened dosing intervals. 4. Prolonged duration of action. 10. Receptor agonists may demonstrate: 1. Irreversible binding. 2. Upregulation with chronic use. 3. Desensitization with continuous use. 4. Inverse relationship between concentration and action. Certainly! Here are the paraphrased questions with multiple-choice options: 11. Drugs that act as receptor antagonists, such as beta blockers, may cause: - 1. Downregulation of the drug receptor - 2. An exaggerated response if abruptly discontinued - 3. Partial blockade of the effects of agonist drugs - 4. An exaggerated response to competitive drug agonists 12. Factors affecting gastric drug absorption include: - 1. Liver enzyme activity - 2. Protein-binding properties of the drug molecule - 3. Lipid solubility of the drug - 4. Ability to chew and swallow 13. Drugs administered via IV: - 1. Begin distribution into the body immediately - 2. Are easily absorbed if they are nonionized - 3. May use pinocytosis to be absorbed - 4. Do not need to be lipid soluble in order to be easily absorbed 14. When a medication is added to a regimen for a synergistic effect, the combined effect of the drugs is: - 1. The sum of the effects of each drug individually - 2. Greater than the sum of the effects of each drug individually - 3. Less than the effect of each drug individually - 4. Not predictable, as it varies with each individual 15. Which of the following statements about bioavailability is true? - 1. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained-release mechanisms. - 2. All brands of a drug have the same bioavailability. - 3. Drugs that are administered more than once a day have greater bioavailability than drugs given once daily. - 4. Combining an active drug with an inert substance does not affect bioavailability. 16. Which of the following statements about the major distribution barriers (blood-brain or fetal-placental) is true? - 1. Water soluble and ionized drugs cross these barriers rapidly. - 2. The blood-brain barrier slows the entry of many drugs into and from brain cells. - 3. The fetal-placental barrier protects the fetus from drugs taken by the mother. - 4. Lipid-soluble drugs do not pass these barriers and are safe for pregnant women. 17. Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both of these types of reactions is to: - 1. Inactivate prodrugs before they can be activated by target tissues - 2. Change the drugs so they can cross plasma membranes - 3. Change drug molecules to a form that an excretory organ can excrete - 4. Make these drugs more ionized and polar to facilitate excretion 18. Once they have been metabolized by the liver, the metabolites may be: - 1. More active than the parent drug - 2. Less active than the parent drug - 3. Totally