NURS 5334 PHARMA MIDTERM 2 PQ EXAM REAL QUESTIONS AND CORRECT DETAILED ANSWERS (CORRECT VERIFIED SOLUTIONS) LATEST UPDATED VERSION GUARANTEED PASS.

The substance is contraindicated to use in dogs a. none of them b. metamizole sodium c. Ibuprofen d. both of them c. ibuprofen N-acetylcysteine is a mucolytic and also the antidote for paracetamol poisoning a. True b. False a. True This is a muscarinic receptor antagonist a. both of them b. none of them c. ipratropium d. betanechol c. Ipratropium treatment of incontinency a. a1 receptor agonist b. a2 receptor antagonists c. B1 receptor antagonist d. B receptor agonist e. B2 receptor agonist a. A1 receptor agonist inducing vasoconstriction in nose drops a. a1 receptor agonist b. a2 receptor antagonists c. B1 receptor antagonist d. B receptor agonist e. B2 receptor agonist a. A1 receptor agonists N-acetylcysteine is a mucolytic and also the antidote for paracetamol poisoning a. true b. false a. true Pair the listed substances used in opthalmology with the statements, all of them can be used only once: Immunosuppressive agent which can be used e.g. in keratoconjunctivitis sicca a. Cyclosporine b. Timolol c. Pilocarpine d. Atropine e. Oxybuprocaine a. cyclosporine Pair the listed substances used in opthalmology with the statements, all of them can be used only once: Drug that is used for treating glaucoma, which decreases production of the aqueous humor and increases its outflow a. Cyclosporine b. Timolol c. Pilocarpine d. Atropine e. Oxybuprocaine b. timolol Pair the listed substances used in opthalmology with the statements, all of them can be used only once: Drug that is used for treating glaucoma, which increases the outflow of aqueous humour but has no effect on its production a. Cyclosporine b. Timolol c. Pilocarpine d. Atropine e. Oxybuprocaine c. pilocarpine Pair the listed substances used in opthalmology with the statements, all of them can be used only once: Mydriatic, used for the treatment of uveitis a. Cyclosporine b. Timolol c. Pilocarpine d. Atropine e. Oxybuprocaine d. atropine Pair the listed substances used in opthalmology with the statements, all of them can be used only once: Thanks to its lipophilicity, this substance can be used for local anaesthesia for opthalmologic patients a. Cyclosporine b. Timolol c. Pilocarpine d. Atropine e. Oxybuprocaine e. Oxybuprocaine Non selective anti-inflammatory drug with pronounced antifever effect, which can be used in cats a. Ketoprofen b. Mavacoxib c. Droperidol d. Acepromazine e. Metamizole f. Lokivetmab a. ketoprofen Thanks to its extremely long half life, monthly administration is enough for its anti-inflammatory effect a. Ketoprofen b. Mavacoxib c. Droperidol d. Acepromazine e. Metamizole f. Lokivetmab b. mavacoxib Phenothiazine derivate with antiemetic and sedative effect, it can be used in travel sickness a. Ketoprofen b. Mavacoxib c. Droperidol d. Acepromazine e. Metamizole f. Lokivetmab D. acepromazine A minor analgesic with spasmolytic activity a. Ketoprofen b. Mavacoxib c. Droperidol d. Acepromazine e. Metamizole f. Lokivetmab e. metamizol A relatively new drug with pronounced antipruritic effect, administered monthly as an SC injection a. Ketoprofen b. Mavacoxib c. Droperidol d. Acepromazine e. Metamizole f. Lokivetmab f. lokivetmab Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Carprofen a. COX-2 (more) selective b. traditional a. COX-2 (more) selective Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Ketoprofen a. COX-2 (more) selective b. traditional b. traditional Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Firocoxib a. COX-2 (more) selective b. traditional a. COX-2 (more) selective Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Flunixin a. COX-2 (more) selective b. traditional b. traditional Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Mavacoxib a. COX-2 (more) selective b. traditional a. COX-2 (more) selective Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Acetylsalicylic acid a. COX-2 (more) selective b. traditional b. traditional Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Robenacoxib a. COX-2 (more) selective b. traditional a. COX-2 (more) selective Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs) :Tolfenamic acid a. COX-2 (more) selective b. traditional b. traditional Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Ibuprofen a. COX-2 (more) selective b. traditional b. traditional Categorise the NSAID agents regarding their selectivity on COX-2 enzyme (in case of dogs): Meloxicam a. COX-2 (more) selective b. traditional a. COX-2 (more) selective Categorize the drugs used in heart failure based on their effect! Amlodipine a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload e. Decrease Afterload Categorize the drugs used in heart failure based on their effect! Digoxin a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload a. Increase contractility Categorize the drugs used in heart failure based on their effect! Torsemide a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload c. Decrease Preload Categorize the drugs used in heart failure based on their effect! Losartan a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload b. Decrease Preload + Afterload Categorize the drugs used in heart failure based on their effect! Pimobendane a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload d. All of them Categorize the drugs used in heart failure based on their effect! Mexiletine a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload f. none of them f. none of them Categorize the drugs used in heart failure based on their effect! Chlorothiazide a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload f. none of them c. Decrease Preload Categorize the drugs used in heart failure based on their effect! Enalapril a. Increase contractility b. Decrease Preload + Afterload c. Decrease Preload d. All of them e. Decrease Afterload f. none of them b. Decrease Preload + Afterload Sedative drug with pronounced antiemetic action a. phenobarbital b. xylazine c. diazepam d. acepromazine d. Acepromazine Which mucolytic is an antidote of paracetamol poisoning? a. guaifenesin b. acetylcysteine c. ambroxol d. bromhexine lcysteine Which substance is NOT an expectorant? a. guaifenesin b. bromhexine c. carbocysteine d. thyme volatile oil c. carbocysteine How can B2 agonists be administered? a. via inhalation b. orally (tablet) c. as an injection d. each d. each Its vasodilatory effect is baes on angiotensin converts enzyme (ACE) inhibition: a. pimobendane b. ramipril c. Theophylline d. Digoxin b. ramipril Bromhexine's effect is based on: a. activation of serous glands b. increasing ciliary movement c. dissolving the mucus d. each of these d. each of these What is the indication of antitussive drugs? a. increased mucus-secretion b. severed, exhausting dry coughing c. both of them d. none of them b. Severe exhausting dry coughing In which case can zafirlukast be used? a. atopic dermatitis b. osteoarthritis c. kennel cough d. feline asthma d. feline asthma Its cardiovascular side effects are negligible: a. propofol b. xylazine c. medetomidine d. diazepam D. diazepam Choose a parasymnpatholytic for situations listed below Organophosphate poisoning: Atropine Choose a parasymnpatholytic for situations listed below Bradycardia during surgical anaesthesia: Glycopyrrolate Choose a parasymnpatholytic for situations listed below RAO: Ipatropium Choose a parasymnpatholytic for situations listed below Colic in horses: Butyl-scopolamine Choose a parasymnpatholytic for situations listed below Eye fundus examination: tropicamide True or false, among the alpha-2 agonists, dexmetomidine is the safest, because its affinity to alpha-1 receptors is much higher, than to the alpha 2 receptors false Pair the contraindications with the drug groups. Each condition should be written to one drug group, where it has the highest relevance. a. Pseudopregnancy b. heart failure c. serious hypovolemia d. AV-block e. Diabetes mellitus Phenothiazines: Alpha-2 agonists: Benzodiazepines: Phenothiazines: a , c Alpha-2 agonists: b, d, e Benzodiazepines: True or false, Glucocorticoid containing eye drops are contraindicated in conceal ulcers? True True or false, Tropicamide can be used effectively in glaucoma because it can increase the outflow of aqueous humor? False True or false, Procaine can be used as a local anesthetic in eye surgeries, because it is able to penetrate the deep layers of the cornea False True or false, Flourescein dye can stain the damaged cornea: therefore it is used for diagnosing conceal ulcers True True or false, atropine is a short-acting parasympatholytic, it is used in eye drops for fundus examination? False Pair the statements with the drug groups! only 10 answers can ve accepted, further answers will result in point reductions a. they decrease gene expression of the cyclooxyrgenase enzyme b. they inhibit the cyclooxyrgenase enzyne c. Its receptor is blocked by a heat-shock protein before ligand bonding d. It acts via the tyrosine kinase signalling pathway e. Cyclosporin and tacrolimus belong here f. They can be used for immunosepressants g. they can be used for treatment of allergic diseases, eg. allergic dermatitis NSAIDS: Glucocorticoids: Oclacitinb: Calcineurin inhibitors: NSAIDS: B Glucocorticoids: A, G Oclacitinb:G, D Calcineurin inhibitors: E, F, G Drug group A inhibits PLA2 enzyme, while drug group B inhibits C enzyme, therefor A, B and C are: A: glucocorticoids B: NSAIDS C: Cyclooxigenase Fill in the sentence: Substances synthesized by C enzyme are ________, prostacyclins and _________. Prostanglandines, Thromoxines (TXA) Fill in the sentence: Lipoxygenase produces______ and ______, which have an important role in the development of asthma Leukotrienes, Lipoxins Fill in the table below ( active substance, mechanism of action, indication) _______, Beta receptor blocker, Glaucoma Timolol Fill in the table below ( active substance, mechanism of action, indication) Atipamezole, yohimbine, _______, antagonizing medetomidine B2 antagonist _______, short acting B2 receptor agonist, bronchodilation Albuterol Fill in the table below ( active substance, mechanism of action, indication) _________, long acting B2 receptor agonist, Bronchodilation clenbuterol Prescribe package of UBROLEXIN intramammary suspension veterinary authorized medicine or 2 lactating cows for mastitis. The contents of one intramammary syringe should be applied to the affected udder quarter once per day for two days. Withdrawl period for milk: 5 days, meat and offal: 10 days. Pack size: 20 intramammary syringes/carton UBROLEXIN intramammary suspension Give 1 original package containing 20 intramammary syringes/carton Sig. Give 1 intramammary syringe to affected udder water SID for 2 days WP: milk 5 days, meat :10 days Shake well before application for animal treatment onle These animals are under my care No repeat The cremophor containing preparation of this substance causes serious histamine release in dogs, this it can only be administered in cats: a. alphaxalone- alphadolone b. methohexital c. thiopental d. etomidate a. alphaxalone- alphadolone Which of these side effects is the least typical for prednisolone? a. nephrotic effect b. polyuria/polydipsia c. hepatotoxic effect d. gastric ulcer at long term use C. hepatotoxic effect Which agent can be used in ADT (alternate day therapy)? a. beclomethasone b. cortisol c. betamethasone d. methylprednisolone d. methylprednisolone Excellent NSAID for postoperative administration as it does not prolong bleeding time: a. ketoprofen b. tolfenamix acid c. flunixin d. meloxicam d. meloxicam Which drug causes miosis? a. atropine b. tetracaine c. procaine d. pilocarpine d. pilocarpine Mavacoxib... a. can be administered intravenously b. can be administered intramuscularly c. is best absorbed with a mean when given orally d. is best absorbed on an empty stomach when given orally d. is best absorbed on an empty stomach when given orally This antihistamine has a remarkable antiemetic effect eg. in motion sickness a. hydroxyzine b. dimetindene c. dimenhydrinate d. chlorpheniramine c. Dimenhydrinate the use of this drug is contraindicated in glaucoma a. Procaine eye drop b. Atropine eye drop c. Pilocarpine eye drop d. Tetracaine eye drop B. Atropine eye drop Which substance belongs to the leukotriene antagonists? a. Zafirlukast b. Fluticasone c. Ambroxol d. Salbutamol A. Zafirlukast Which nonsteroidal anti inflammatory drug is FORBIDDEN to use in cats ( under any circumstances) a. Meloxicam b. Acetylsalicylic acid c. Diclofenac d. Robemacoxib C. Diclofenac True of false , acepromazine is contraindicated in pseudo pregnancy, it can indirectly increase prolactin production by being a dopamine receptors antagonist False Fill in the blank immunosupressive agent which can be used e.g. in KCS Pilocarpine, atropine, timolol, oxybuprocaine, cyclosporine Cyclosporine Fill in the blank drug that is used for treating glaucoma, which decreases production of the aqueous humour and increases its outflow Pilocarpine, atropine, timolol, oxybuprocaine, cyclosporine Timolol Fill in the blank drug that is used for treating glaucoma, which increases the outflow of aqueous humour but has no effect on its production Pilocarpine, atropine, timolol, oxybuprocaine, cyclosporine Pilocarpine Fill in the blank mydriatic, used for treatment of uveitis Pilocarpine, atropine, timolol, oxybuprocaine, cyclosporine Atropine Categorize NSAID's based on their selectivity ( traditional NSAID v.s. COX-2 selective agents) in dogs ! acetylsalicytic acid, meloxicam , carprofen, flunixin meglumine, mavacoxib, ketoprofen, firocoxib, ibuprofen, robemacoxib, tolfenamic acid COX-2 selective ( or more selective ) drugs meloxicam Carprofen mavacoxib firocoxib robemacoxib NOT COX-2 selective drugs (traditional NSAIDS) acetylsalicylic acid ibuprofen flunixin meglumine tolfenamic acid ketofen Categorize the drugs used in heart failure based on their mechanism of action! Some of the substances should be written in more than one place, but not all of them should be used. In total 10 words should be written in the table furosemide, benazepril, digoxin, pimobendane, lidocaine, hydrochlorothiazide, amlodipine, telmisartan preload decrease afterload decrease, vasodilation contractility increase Preload decrease: furosemide, benazepril, hydrochlorothiazides after load decrease, vasodilation : pimobendan, telmisartan, benazepril, contractility increase : digoxin, amlodipine List the indications of adrenaline! Every correct answer worth 1 point 1. 2. 3. 4. 5. 1. Anaphylaxis 2. bronchoconstriction 3. Cardiac arrest 4. potentiate local anaesthesia 5. vasoconstriction ( local) Thiopental can be administered a. IV,IM,SC b. IV,IM c. IV d. IM C. IV It's microemulsion formulation is highly susceptible to bacterial contamination a. Alphaxalone-alphadolome b. Ketamine c. Thiopental d. Propofol D. Propofol A general anaesthetic with broad therapeutic margin, although it's quick administration might induce cardiovascular side effects or apnoe a. Thiopental b. Etomidate c. Alphaxalone- alphadolone d. Propofol D. Propofol It can cause prolapse of the third eyelid in dogs, cats and horses a. acepromazine b. detomidine c. Xylazine d. diazepam a. acepromazine Sedative that decreases blood pressure hence it cannot be administered to seriously dehydrated animals a. azepromazine b. diazepam c. chloropromazine d. ketamine a. azepromazine Sedative that can cause paradoxical in horses a. romifidine b. detomidine c. midazolam d. acepromazine d. acepromazine In the absence of special label instruction, the multi dose injections can be used ... days after being opened for the first time? a. 21 days b. unlimited c. 28 days d. 4 days c. 28 days Which drug causes cardiovascular depression? a. propfol b. both c. none of them d. etomidate a. propofol Which vehicle is useful for preparation of eye ointment? a. white vaseline b. simple ointment c. cocoa butter d. paraffin ointment a. white vaseline what kind of effect can be expected when using ointments? a. local effect b. neither of them c. both local and systemic effect d. systemic effect c. both local and systemic effect What amino acids are converted into catecholamines (NE, Epi, Dopamine) a. alanine b. proline c. lysine d. tyrosine e. valine d. Tyrosine Which of the following is co-stored and co-released with ATP? a. epinephrine b. norepenephrine c. dopamine d. adrenalin b. norepinephrine NET is a symporter of what ion? a. K b. Ca c. Cl d. Na e. Mg d. Na Beta 2 stimulation leads to an increase in the cellular uptake of what ion, and this decrease in plasma concentration of that ion? a. K b. Ca c. Cl d. Na e. Mg a. K Match the liquid dosage forms according to their route of administration (external use and internal use) a. elixir b. injection c. eardrops d. drench e. tincture f. spot on g. oral solution h. suspension external use: ear drops, tincture, spot on, suspension, drench Internal use: Elixir, injection, oral solution, suspension List the indications of adrenaline 1. 2. 3. 4. 5. 1. vasoconstrictor 2. anaphylaxis 3. adrenaline+lidocaine: prolonged action of local anaesthetic 4. bronchodilator 5. cardiac arrest Categorize the drugs used in heart failure based on their mechanism of action! Some of the substances should be written in more than one place, but not all of them should be used (preload decrease, after load decrease, contractility increase) a. furosemide b. benazepril c. digoxin d. pimobendane e. lidocaine f. hydrocholrothiazide g. amlodipine h. telmisaran Preload decrease: furosemide, benazepril, hydrochlorothiazide afterload decrease, vasodilation: benazepril, amlodipine contractility increase: digoxin The substance is contraindicated to use in dogs a.Metamizole sodium ofen c. Both of them d. None of them B. ibuprofen True or false: N-acetylcysteine is a mucolytic and also the antidote for paracetamol poisoning a. True b. False A. true This is a muscarinic receptor antagonist a. Both of them b. None of them c. Ipatropium d. betanechol c. Ipatropium Treatment of incontinency a. a1 receptor agonist b. a2 receptor antagonists c.B1 receptor antagonist d. B receptor agonist e. B2 receptor agonist a. a1 receptor agonist Antagonizing medetomidine a. a1 receptor agonist b. a2 receptor antagonists c.B1 receptor antagonist d. B receptor agonist e. B2 receptor agonist b. a2 receptor antagonists Treatment of high blood pressure a. a1 receptor agonist b. 1 receptor antagonist c. a2 receptor antagonists d. B1 receptor antagonist e. B receptor agonist f. B2 receptor agonist g. B receptor antagonist b. 1 receptor antagonist Treatment of high blood pressure, tachycardia, methylxanthine poisoning a. a1 receptor agonist b. a2 receptor antagonists c. B1 receptor antagonist d. B receptor agonist e. B2 receptor agonist f. B receptor antagonist f. B receptor antagonist True or false: Tropicamide can be used effectively in glaucoma because it can increase the outflow of aqueous humor a. True b. false b. false True or false: Glucocorticoid containing eye drops are contraindicated in the treatment of corneal ulcers a. true b. false a. true True or false: Procaine can be used as a local anaesthetic in eye surgeries, because it is able to penetrate to deeper layers of the cornea a. true b. false b. false True or false: Cyclosporin and tacrolimus are both calcineurin-inhibitors, they can be used to treat atopic dermatitis, but the latter is much more active than the former a. true b. false a. true True or false: Ipratropium is a safe parasympathomimetic that can be used for bronchodilation is respiratory diseases a. true b. false b. false Bromhexine's effect is based on: a. increasing ciliary movement b. dissolving the mucosa c. activation of serous glands d. all of these d. all of these