NR546 Psychopharm Midterm
1. How does the orbitofrontal cortex (OFC) affect the amygdala?: inhibits and activates the amygdala
2. Wernicke's area is associated with which of the following?: speech compre- hension
3. The limbic system is associated with which of the following: emotion and learning
4. Which brain structure is most associated with long term memory?: hip- pocampus
5. When prescribing psychotropic medications, the PMHNP knows that these medications work within which
specific areas?: mood
6. Which of the following are involved in regulating neurotransmission via ex- citation-secretion coupling?:
voltage-sensitive sodium channels and voltage-sen- sitive calcium channels
7. What system influences the length of time for a drug to achieve efficacy?: -
signal transduction cascades
8. One of the signal transduction cascades, pass the message from a first receptor to a second messenger.: G
protein linked systems
9. Human central nervous system communication at synapses is which of the following?: chemical
10.Which of the following is an excitatory neurotransmitter?: glutamate
11.Which statement correctly pairs the pharmacodynamic effect with its defi- nition?: antagonist effect - drug
binds to receptor, but does not activate a response
12.A major current hypothesis for the cause of schizophrenia proposes that N-methyl-d-aspartate (NMDA)
receptors may be which of the following? Correct!: hypofunctional
13.Which medication is least associated with weight gain?: aripiprazole
14.Which dopamine pathway is associated with positive symptoms of schiz- ophrenia?: mesolimbic pathway
15.Which pathway is associated with negative symptoms?: The mesocortical pathway
16.Is part of the extrapyramidal nervous system and associated with ex- trapyramidal symptoms (EPS):
nigrostriatal pathway
17.This pathway is associated with hyperprolactinemia.: The tuberoinfundibu- lar pathway
18.A 34-year old male recently began experiencing breast secretions while receiving risperidone . Which
dopamine pathway is associated with this side effect?: tuberoinfundibular pathway
, NR546 Psychopharm Midterm
19.A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of schizophrenia. Regarding
affinity, atypical antipsychotics demon-
, NR546 Psychopharm Midterm
strate which of the following most often?: Atypical antipsychotics have equal positive symptom antipsychotic actions a
low extrapyramidal symptoms.
20.is a syndrome that can be associated with several different psychiatric disorders. Symptoms include
hallucinations, delusions, disorganized speech, disorganized behavior, and distortions of reality. This syndrome
can affect a person's cognition, affective response, communication, capacity to recognize reality, and ability to
relate to others.: psychosis
21.What Diagnosis require the presence of psychosis?: schizophrenia substance-induced psychotic
disorders
schizophreniform disorder
schizoaffecive disorder delusional
disorder
brief psychotic disorder
psychotic disorder due to a medical condition
22.What diagnosis has a diagnosis of psychosis as a feature?: mania depression
cognitive disorders
dementia
23.What are some positive symptoms?: Hallucinations Delusions
Thought disorder Hostility
Excitability
24.What are some Negative symptoms?: Affective flattening Alogia
Anhedonia
Amotivation
Asociality
25.What area of the brain is associated with negative and affective symp- toms?: Mesocortical and
ventromedial prefrontal cortex:
26.What area of the brain is associated with cognitive symptoms?: Dorsolat- eral
27.What area of the brain is associated with aggressive, impulsive symp- toms?: Orbitofrontal and
connections to the amygdala
28.Non-selectively blocks dopamine D2 receptors, specifically in mesolimbic pathway. Improves Positive
1. How does the orbitofrontal cortex (OFC) affect the amygdala?: inhibits and activates the amygdala
2. Wernicke's area is associated with which of the following?: speech compre- hension
3. The limbic system is associated with which of the following: emotion and learning
4. Which brain structure is most associated with long term memory?: hip- pocampus
5. When prescribing psychotropic medications, the PMHNP knows that these medications work within which
specific areas?: mood
6. Which of the following are involved in regulating neurotransmission via ex- citation-secretion coupling?:
voltage-sensitive sodium channels and voltage-sen- sitive calcium channels
7. What system influences the length of time for a drug to achieve efficacy?: -
signal transduction cascades
8. One of the signal transduction cascades, pass the message from a first receptor to a second messenger.: G
protein linked systems
9. Human central nervous system communication at synapses is which of the following?: chemical
10.Which of the following is an excitatory neurotransmitter?: glutamate
11.Which statement correctly pairs the pharmacodynamic effect with its defi- nition?: antagonist effect - drug
binds to receptor, but does not activate a response
12.A major current hypothesis for the cause of schizophrenia proposes that N-methyl-d-aspartate (NMDA)
receptors may be which of the following? Correct!: hypofunctional
13.Which medication is least associated with weight gain?: aripiprazole
14.Which dopamine pathway is associated with positive symptoms of schiz- ophrenia?: mesolimbic pathway
15.Which pathway is associated with negative symptoms?: The mesocortical pathway
16.Is part of the extrapyramidal nervous system and associated with ex- trapyramidal symptoms (EPS):
nigrostriatal pathway
17.This pathway is associated with hyperprolactinemia.: The tuberoinfundibu- lar pathway
18.A 34-year old male recently began experiencing breast secretions while receiving risperidone . Which
dopamine pathway is associated with this side effect?: tuberoinfundibular pathway
, NR546 Psychopharm Midterm
19.A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of schizophrenia. Regarding
affinity, atypical antipsychotics demon-
, NR546 Psychopharm Midterm
strate which of the following most often?: Atypical antipsychotics have equal positive symptom antipsychotic actions a
low extrapyramidal symptoms.
20.is a syndrome that can be associated with several different psychiatric disorders. Symptoms include
hallucinations, delusions, disorganized speech, disorganized behavior, and distortions of reality. This syndrome
can affect a person's cognition, affective response, communication, capacity to recognize reality, and ability to
relate to others.: psychosis
21.What Diagnosis require the presence of psychosis?: schizophrenia substance-induced psychotic
disorders
schizophreniform disorder
schizoaffecive disorder delusional
disorder
brief psychotic disorder
psychotic disorder due to a medical condition
22.What diagnosis has a diagnosis of psychosis as a feature?: mania depression
cognitive disorders
dementia
23.What are some positive symptoms?: Hallucinations Delusions
Thought disorder Hostility
Excitability
24.What are some Negative symptoms?: Affective flattening Alogia
Anhedonia
Amotivation
Asociality
25.What area of the brain is associated with negative and affective symp- toms?: Mesocortical and
ventromedial prefrontal cortex:
26.What area of the brain is associated with cognitive symptoms?: Dorsolat- eral
27.What area of the brain is associated with aggressive, impulsive symp- toms?: Orbitofrontal and
connections to the amygdala
28.Non-selectively blocks dopamine D2 receptors, specifically in mesolimbic pathway. Improves Positive