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MODERN BLOOD|
BANKING &
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TRANSFUSION
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PRACTICES 6TH
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EDITIONDENISEM.
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HARMENING
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,TEST BANK FOR MODERN BLOOD BANKING
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& TRANSFUSION PRACTICES
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6TH EDITION
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DENISE M. HARMENING
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, Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choice |
Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of theATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis | |
b. Luebering-Rapoport shunt d. Methemoglobin reductase | | | |
2. Aunit of blood was returned to the blood bank before it was spiked.Apparently the patient’s IV failed. The unit
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of blood was outside the blood bank for 35 minutes. Which of the statements below is most accurate?
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a. The unit of blood should be discarded immediately. | | | | | | |
b. The unit of blood can be returned to inventory. | | | | | | | |
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours. | | | | | | | | |
3. What is the average diameter of a platelet?
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a. 5 to 10 µm | | | c. 1 to 2 µm | | |
b. 2 to 4 µm | | | d. 4 to 6 µm| | | | |
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the tissues
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when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% | |
5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count | |
b. Initial pH d. All of the above | | | | | |
6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a result of
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loss of RBC membrane?
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a. Spherocytes c. Burr cells |
b. Target cells d. Schistocytes | | |
7. What does the term autologous transfusion refer to?
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a. Aparent donating blood for his or her child
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b. An individual donating blood for a friend | | | | | |
c. An individual donating blood for a relative | | | | | |
d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
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a. Iron metabolism | c. Oxygen transport |
b. Porphyrin synthesis | d. Signal transduction
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9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of theABO antigen attachment. | | | | | |
b. RBC membrane. d. Hemoglobin structure.
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, | 10. | What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate | | | | |
b. 40% protein, 8% lipid, 52% carbohydrate | | | | |
c. 8% protein, 52% lipid, 40% carbohydrate | | | | |
d. 8% lipid, 40% carbohydrate, 52% protein | | | | |
| 11. | All of the following biochemical changes are associated with loss of red blood cell viability upon storage
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except:
a. Decreased pH. c. Increased ATP level. | | |
b. Loss of red blood cell function. d. Decreased glucose consumption.
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| 12. | Which red blood cell preservative has a storage time of 35 days?
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a. ACD c. AS-1
b. CPDA-1 d. CPD | |
| 13. | The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. | |
| 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from the
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bone marrow?
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a. 30% c. 10%
b. 50% d. 25% | |
| 15. What is the major biochemical consideration in platelet storage?
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a. Glucose metabolism c. Production of carbon dioxide | | | |
b. Oxygen supply d. Regulation of pH | | | | |
| 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs of
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alkalosis?|
a. Normal c. Shift to the right | | |
b. Shift to the left d. None of the above
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| 17. | Name the main lipid components of a red blood cell membrane.
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A | | |
| 18. | The ABO blood groups were discovered in 1901 by whom?
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a. Charles Drew c. Loutit and Mollison | | |
b. Karl Landsteiner d. Edward Lindeman
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| 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in the
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corner of the department until discovered 36 hours later. What would the appropriate action be for the blood
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banker? |
a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be OK
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to accept the unit into inventory.
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b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
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discarded because the pH has probably dropped too low and platelet activation has been | | | | | | | | | | | | |
compromised. |
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
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