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Class notes NCM 106

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This notes are my summarized version of our Pharmacology classes! These are short, but very comprehensive.

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Vertical Transmissions -​ Tx of uncomplicated N. gonorrhoeae
-​ the passage of infecting organisms should be with ceftriaxone 500 mg
from mother to neonate. IM as a single dose. Tx of co –
infection with C. trachomatis, or
Bacterial Pathogens when chlamydia is not excluded,
-​ can be effectively treated with should be with oral doxycycline 100
antibiotic therapy. mg BID x 7 days.
-​ When present, common symptoms
include vaginal discharge, urethral Syphilis
discharge or burning (in men), -​ is caused by the bacteria
genital ulcers, and abdominal pain. Treponema pallidum; if not treated
early in the infectious process, it
Bacterial Vaginosis produces systematic disease that
-​ causes a large amount of can be fatal.
homogenous, thin, white vaginal -​ The disease is divided into three
discharge with a strong fishy odor. stages: primary, secondary, and
-​ BV is treated with Metronidazole 500 tertiary.
mg by mouth (PO) twice a day for 7
days. Primary Syphilis
-​ Because Metronidazole can cause -​ present with a sore, or chancre, at
stomach upset, it should be taken the site where the infection entered
with food or a full glass of water or the body – typically, the penis in men
milk. and outer genitals or inner vagina in
women.
Chlamydia
-​ the most common STI in the United Secondary Syphilis
States in young adults. -​ characterized by a skin rash that
-​ CDC recommends azithromycin 1 g appears 2 to 8 weeks after the
orally in a single dose as treatment chancre. It may occur anywhere on
for C. trachomatis infections or the body, commonly on the hands
doxycycline 100 mg PO BID x 7 and soles of the feet; the rash
days. usually does not itch.

Gonorrhea Tertiary Syphilis
-​ the second most common -​ may occur as early as 1 year after
communicable disease. infection or at any time during an
-​ In men, infection by N. gonorrhoeae untreated person’s lifetime. Large
causes a greenish – yellow or sores inside the body or on the skin
whitish discharge from the penis, occur in the tertiary stage, along with
accompanied by burning with cardiovascular and ocular syphilis
urination. and neurosyphilis.
-​ In women, N. gonorrhoeae is
frequently asymptomatic.

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