5 stages of addiction Right Ans - 1. First Use
2. Continued use
3. Tolerance
4. Dependence
5. Addiction
6% of U.S patients misuse their pain management prescriptions. Three
common patient populations affected are Cancer, MVA and __________ ________
Right Ans - Sickle Cell
This medication acts on the same opioid receptors as commonly abused
opioids without reaching a point of euphoria. Also being long acting it has
been used for over 40 years in countless patients quests towards recovery.
Right Ans - Methadone
Which of these medications are used for treating alcohol abuse?
Acamprosate
Varenicline
Methadone
Bupropion Right Ans - Acamprosate
Which of these medications are used for tobacco disorder?
Acamprosate
Varenicline
Methadone
Bupropion Right Ans - Varenicline
Bupropion
This substance is a full agonist of trace amine-associated receptors (TAAR1).
Activation TAAR1 causes the increase of cAMP and inhibition of serotonin,
dopamine, and norepinephrine transporters. The inhibition of monoamine
transporters causes the reuptake and metabolism of catecholamines. Right
Ans - Methamphetamine
,The following are "_________ _______" for methamphetamine: meth, crystal meth,
crystal, speed, scootie, yellow powder, crank, ice, spoosh, glass, chalk, redneck
cocaine, yellow barn, Tina, and tick-tick. Right Ans - street names
Patients under the influence of methamphetamine can have the following
signs or symptoms: ___________ appetite, nausea, psychosis, tachycardia,
hypertension, ___________ body temperature, panic attack, mydriasis, __________
sleep patterns, violent, bizarre, and erratic behavior, hallucinations,
irritability, seizures, and death from high doses. Right Ans - decreased
increased
disturbed
A 65-year-old female presents to the clinic to seek a re-prescription of her
pain medication. She had a motor vehicle collision (MVC) 8 months ago that
left her with chronic neuralgia in bilateral arms along with low back pain. She
was prescribed oxycodone/acetaminophen 7.5/325 mg q6 hours. Her last
scheduled refill was 20 days ago with a 30 day supply. She returns early
claiming she needed multiple dosages sooner than directed due to unmanaged
pain. Current vital signs are normal, but she is diaphoretic, tearing, restless,
and occasionally yawning. When the provider explains, controlled
medications cannot be prescribed in this manner, the patient states, "You
don't understand. I need to feel normal. Without it, I feel worse than I used to
feel at baseline. Please!" What stage of addiction is the patient in and what
medication can be used to help her symptoms?
Choices:
1. Tolerance and acamprosate
2. Tolerance and Right Ans - Dependence and methadone
A patient presents to the emergency department with agitation, mydriasis,
hypertension, and tachycardia. He states that he snorted "some crystals" with
friends and that he feels energetic and anxious. He reports that his friends told
him this is a treatment for weight loss and this is the reason why he tried it.
Which is true of the drug most likely used by this patient?
Choices:
1. Partial agonist of trace amine-associated receptors (TAAR1)
2. Gamma-aminobutyric acid (GABA) receptor agonist
3. Full agonist of trace amine-associated receptors (TAAR1)
,4. Full antagonist of dopamine receptors Right Ans - Full agonist of trace
amine-associated receptors (TAAR1)
A 35-year-old woman comes in for her wellness check-up. She has a 13-year-
old son who is going to be starting high school next year and often hear him
and his friends discuss ways to prepare for high school, so they fit in. The
mother is concerned her son may use drugs as he often talks about the
partying. She wants to know what she can do it prepare him to avoid smoking
cannabis given its surge in popularity amongst youth. What is the most
common reason for marijuana use, amongst teenagers and young adults?
Choices:
1. Stress management
2. Experimentation
3. Social conformity
4. Pleasurable sensation Right Ans - Social conformity
A young adult patient is dropped off outside the emergency department by
her friends, and they drive off before any history can be obtained. The patient
has altered mental status and shows signs of intoxication. Sudden dorsiflexion
of her ankle produces a rhythmic reproduction of her ankle jerk reflex. Which
of the following drugs did she most likely ingest?
Choices:
1. Alcohol
2. 3,4-Methylenedioxymethamphetamine (MDMA)
3. Phencyclidine
4. Cannabis Right Ans - 3,4-Methylenedioxymethamphetamine (MDMA)
Several classes of common street drugs such as cocaine, ecstasy (MDMA), and
amphetamines, increase serotonin levels, which is part of what contributes to
the pleasurable and addictive aspects of their use, and also what can produce
a __________ syndrome and __________. Right Ans - serotonin
clonus
Psychiatric medications such as monoamine oxidase inhibitors (MAOI),
selective serotonin reuptake inhibitors (SSRI), serotonin-norepinephrine
reuptake inhibitors (SNRI), and tricyclic antidepressants (TCA) manipulate
, serotonin levels to improve __________, but too much can produce clonus as part
of serotonin ____________. Right Ans - mood
syndrome
____________ nervous system depressants like alcohol and opiates can diminish
deep tendon __________ as opposed to producing clonus. Right Ans - Central
reflexes
A 66-year-old male was prescribed pain medication after a fracture followed
by surgery 6 months ago. Since then, his primary care provider has noticed
frequent visits to the office asking for pain medication and multiple injuries
justifying the use of it. Every time there are different vague complaints, but
that of pain is consistent. On his last visit, the primary care took a firm stand
and did not agree to continue prescribing the opioids. Today he visits in a
restless state. Which of the following do you suspect to see on history or
physical exam in this patient?
Choices:
1. Constipation
2. Miosis
3. Dilated pupils
4. Bradycardia Right Ans - Dilated pupils
Opioid withdrawal onset varies with the type of opioid used. Heroin
withdrawal begins in as little as ___ hours, whereas methadone may take 2 to 3
_______. Right Ans - 5
days
Opiod withdrawal symptoms may last days to weeks known as protracted
abstinence syndrome. Signs and symptoms of withdrawal include ___________
cramps, agitation, anxiety, cravings, diarrhea, dilated pupils, high blood
pressure, insomnia, goosebumps, muscle pains, ________ nose, shakiness,
sneezing, sweating, tachycardia, and tearing. Right Ans - abdominal
runny
A pregnant female, admitted for possible pyelonephritis, is complaining of
significant anxiety, tremulousness, and irritability. Upon assessment, she is
noted to have a blood pressure of 156/94 mmHg, pulse 103 bpm, and is
complaining of nausea. Which of the following screening tools for this