WITH COMPLETE SOLUTIONS VERIFIED
What are chronic infectious diseases
incurable, progressive, long-term consequences if untreated
what are 90-90-90 targets for HIV
90% of all people with HIV would have their infection diagnosed, 90% of those with
diagnosed infection would be prescribed antiretroviral treatment (ART), and 90% of
those treated would by virally suppressed
what are symptoms of acute HIV infection
flu-like symptoms
how long does acute HIV infection last
about 1-2 weeks
what does early chronic HIV infection look like
generally asymptomatic, flu-like, persistent generalized lymphadenopathy,
thrombocytopenia
what are signs and symptoms of intermediate chronic HIV infection
CD4+ T cells drop to 200-500 cells
viral load increases
thrush, shingles, oral hairy leukoplakia, herpes, bacterial infections, sarcoma
how is HIV diagnosed
, screening test for HIV-specific antibodies, can take 2 months to detect
what are four basic questions to ask if assessing for possibility of HIV infection
received blood transfusion or clotting factors before 1985, shared needles syringes etc.
with another person, sexually active, history of STI
What are main treatment goals for HIV
- keep viral load low
- maintain immune function
- keep QOL
- reduce potential for transmission
- prevent opportunistic disease and new infections
- reduce disability
- prevent reinfection
what are the cons of antiretroviral therapy
complex, interactions, high medication resistance, expensive
why is it difficult to create an HIV vaccine
hides inside cells, mutates rapidly, two strains that cause infection
why do we use combination therapy for HIV
attacks viral replication in several different ways, makes it more difficult to recover and
decreases likelihood of resistance
adverse effects of antiretrovirals
GI issues, headache, fatigue, anemia, rash, hyperlipidemia, weight gain, kidney
damage, bone disease, cardiovascular disease
What is PrEP vs. PEP?