Advanced Pathophysiology
Midterm Exam Review (Qns & Ans)
2025
1. Which of the following is a common cause of chronic
obstructive pulmonary disease (COPD) in adults?
- A. Genetic mutations
- B. Viral infections
- C. Smoking
- D. Allergies
- ANS: C. Smoking
- Rationale: Smoking is a major risk factor for the
development of COPD in adults.
©2024/2025
,2. What is the primary pathophysiological mechanism of type 1
diabetes mellitus?
- A. Insulin resistance
- B. Autoimmune destruction of pancreatic beta cells
- C. Increased hepatic glucose production
- D. Obesity
- ANS: B. Autoimmune destruction of pancreatic beta cells
- Rationale: Type 1 diabetes mellitus is characterized by the
autoimmune destruction of insulin-producing beta cells in the
pancreas.
3. Which of the following is a characteristic feature of
Alzheimer's disease?
- A. Hyperactivity
- B. Memory loss
- C. Muscle weakness
- D. Joint pain
- ANS: B. Memory loss
- Rationale: Memory loss is a hallmark symptom of
Alzheimer's disease, a neurodegenerative disorder.
©2024/2025
, 4. What is the primary cause of sickle cell anemia?
- A. Iron deficiency
- B. Vitamin B12 deficiency
- C. Genetic mutation in the hemoglobin gene
- D. Chronic inflammation
- ANS: C. Genetic mutation in the hemoglobin gene
- Rationale: Sickle cell anemia is caused by a genetic
mutation in the hemoglobin gene, leading to the production of
abnormal hemoglobin.
5. Which of the following is a common complication of
untreated hypertension?
- A. Osteoporosis
- B. Stroke
- C. Asthma
- D. Anemia
- ANS: B. Stroke
- Rationale: Untreated hypertension can lead to serious
complications such as stroke, heart attack, and kidney damage.
Fill-in-the-Blank Questions
©2024/2025