TEST BANK c
PATHOPHYSIOLOGY
The Biologic Basis For Disease InAdults
c c c c c c c
And Children
c
8THEDITION BY KATHRYN L.MCC
c c c c c
ANCE
,McCance:cPathophysiology:cThecBiologiccBasiscforcDiseasecincAdultscandcChildrenc(8thcEdition)cTESTcBANK
CONTENTS:
Chapterc01:cCellularcBiology
Chapterc02:cAlteredcCellularcandcTissuecBiology:cEnvironmentalcAgents
Chapterc03:cThecCellularcEnvironment:cFluidscandcElectrolytes,cAcidscandcBases
Chapterc04:cGenescandcGeneticcDiseases
Chapterc05:cGenes,cEnvironment-Lifestyle,candcCommoncDiseases
Chapterc06:cEpigeneticscandcDisease
Chapterc07:cInnatecImmunity:cInflammationcandcWoundcHealing
Chapterc08:cAdaptivecImmunity
Chapterc09:cAlterationscincImmunitycandcInflammation
Chapterc10:cInfection
Chapterc11:cStresscandcDisease
Chapterc12:cCancercBiology
Chapterc13:cCancercEpidemiology
Chapterc14:cCancercincChildren
Chapterc15:cStructurecandcFunctioncofcthecNeurologiccSystem
Chapterc16:cPain,cTemperaturecRegulation,cSleep,candcSensorycFunction
Chapterc17:cAlterationscincCognitivecSystems,cCerebralcHemodynamics,candcMotorcFunction
Chapterc18:cDisorderscofcthecCentralcandcPeripheralcNervouscSystemscandcthecNeuromuscularcJunction
Chapterc19:cNeurobiologycofcSchizophrenia,cMoodcDisorders,candcAnxietycDisorders
Chapterc20:cAlterationscofcNeurologiccFunctioncincChildren
Chapterc21:cMechanismscofcHormonalcRegulation
Chapterc22:cAlterationscofcHormonalcRegulation
Chapterc23:cObesitycandcDisorderscofcNutrition
Chapterc24:cStructurecandcFunctioncofcthecReproductivecSystems
Chapterc25:cAlterationscofcthecFemalecReproductivecSystem
Chapterc26:cAlterationscofcthecMalecReproductivecSystem
Chapterc27:cSexuallycTransmittedcInfections
Chapterc28:cStructurecandcFunctioncofcthecHematologiccSystem
Chapterc29:cAlterationscofcErythrocytes,cPlatelets,candcHemostaticcFunction
Chapterc30:cAlterationscofcLeukocytecandcLymphoidcFunction
Chapterc31:cAlterationscofcHematologiccFunctioncincChildren
Chapterc32:cStructurecandcFunctioncofcthecCardiovascularcandcLymphaticcSystems
Chapterc33:cAlterationscofcCardiovascularcFunction
Chapterc34:cAlterationscofcCardiovascularcFunctioncincChildren
Chapterc35:cStructurecandcFunctioncofcthecPulmonarycSystem
Chapterc36:cAlterationscofcPulmonarycFunction
Chapterc37:cAlterationscofcPulmonarycFunctioncincChildren
Chapterc38:cStructurecandcFunctioncofcthecRenalcandcUrologiccSystems
Chapterc39:cAlterationscofcRenalcandcUrinarycTractcFunction
Chapterc40:cAlterationscofcRenalcandcUrinarycTractcFunctioncincChildren
Chapterc41:cStructurecandcFunctioncofcthecDigestivecSystem
Chapterc42:cAlterationscofcDigestivecFunction
Chapterc43:cAlterationscofcDigestivecFunctioncincChildren
Chapterc44:cStructurecandcFunctioncofcthecMusculoskeletalcSystem
Chapterc45:cAlterationscofcMusculoskeletalcFunction
Chapterc46:cAlterationscofcMusculoskeletalcFunctioncincChildren
Chapterc47:cStructure,cFunction,candcDisorderscofcthecIntegument
Chapterc48:cAlterationscofcthecIntegumentcincChildren
Chapterc49:cShock,cMultiplecOrgancDysfunctioncSyndrome,candcBurnscincAdults
Chapterc50:cShock,cMultiplecOrgancDysfunctioncSyndrome,candcBurnscincChildren
, McCance:cPathophysiology:cThecBiologiccBasiscforcDiseasecincAdultscandcChildrenc(8thcEdition)cTESTcBANK
Partc1:cCENTRALcCONCEPTScOFcPATHOPHYSIOLOGY:cCELLScANDcTISSUESc
UnitcI:cTHEcCELL
CHAPTERc01:cCELLULARcBIOLOGY
MULTIPLEcCHOICE
1. Whichcstatementcbestcdescribesctheccellularcfunctioncofcmetaboliccabsorption?
a. Cellsccancproducecproteins.
b. Cellsccancsecretecdigestivecenzymes.
c. Cellsccanctakecincandcusecnutrients.
d. Cellsccancsynthesizecfats.
ANS:c C
Incmetaboliccabsorption,callccellsctakecincandcusecnutrientscandcothercsubstancescfromctheircsurroun
dings.cThecremainingcoptionscarecnotcinclusivecinctheircdescriptionscofccellularcmetaboliccabsorptio
n.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
2. Whereciscmostcofcaccell’scgeneticcinformation,cincludingcRNAcandcDNA,ccontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:c C
Thecnucleusccontainscthecnucleolus,cacsmallcdensecstructureccomposedclargelycofcRNA,cmostcofcth
eccellularcDNA,candcthecDNA-
bindingcproteins,csuchcascthechistones,cwhichcregulatecitscactivity.cThecmitochondriacarecresponsi
blecforccellularcrespirationcandcenergycproduction.
Ribosomes’cchiefcfunctioncisctocprovidecsitescforccellularcproteincsynthesis.cLysosomescfunctioncas
cthecintracellularcdigestivecsystem.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
3. Whichccomponentcofctheccellcproduceschydrogencperoxidec(H2O2)cbycusingcoxygenctocremovech
ydrogencatomscfromcspecificcsubstratescincancoxidativecreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:c B
, McCance:cPathophysiology:cThecBiologiccBasiscforcDiseasecincAdultscandcChildrenc(8thcEdition)cTESTcBANK
Peroxisomescarecsocnamedcbecausectheycusuallyccontaincenzymescthatcusecoxygenctocremovechydr
ogencatomscfromcspecificcsubstratescincancoxidativecreactioncthatcproducescH2O2,cwhichciscacpower
fulcoxidantcandcpotentiallycdestructivecifcitcaccumulatescorcescapescfromcperoxisomes.
RibosomescarecRNA-
proteinccomplexesc(nucleoproteins)cthatcarecsynthesizedcincthecnucleoluscandcsecretedcintoctheccyt
oplasmcthroughcporescincthecnuclearcenvelopeccalledcnuclearcporeccomplexes.cLysosomescarecsacl
ikecstructurescthatcoriginatecfromcthecGolgiccomplexcandccontaincmorecthanc40cdigestivecenzymesc
calledchydrolases,cwhichccatalyzecbondscincproteins,clipids,cnucleiccacids,candccarbohydrates.cAnc
endosomeciscacvesicalcthatchascbeencpinchedcoffcfromctheccellularcmembrane.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
4. Whichccellccomponentcisccapablecofccellularcautodigestioncwhencitciscreleasedcduringccellcinjury?
a. Ribosome
b. Golgiccomplex
c. Smoothcendoplasmiccreticulum
d. Lysosomes
ANS:c D
Theclysosomalcmembranecactscascacprotectivecshieldcbetweencthecpowerfulcdigestivecenzymescwit
hinctheclysosomecandctheccytoplasm,cpreventingctheircleakagecintoctheccytoplasmiccmatrix.cDisrup
tioncofcthecmembranecbycvariousctreatmentscorccellularcinjurycleadsctocacreleasecofctheclysosomalce
nzymes,cwhichccancthencreactcwithctheircspecificcsubstrates,ccausingccellularcself-
cdigestion.cThecchiefcfunctioncofcacribosomecisctocprovidecsitescforccellularcproteincsynthesis.cThecG
olgiccomplexciscacnetworkcofcflattened,csmoothcvesiclescandcmembranescoftenclocatedcnearctheccellc
nucleus.cThecsmoothcendoplasmiccreticulumciscinvolvedcincsteroidchormonecproductioncandcremov
ingctoxiccsubstancescfromctheccell.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
5. WhichccAMP-mediatedcresponseciscrelatedctocantidiureticchormone?
a. Increasedcheartcratecandcforcecofccontraction
b. Secretioncofccortisol
c. Increasedcretentioncofcwater
d. Breakdowncofcfat
ANS:c C
Antidiureticchormonecleadsctocincreasedcretentioncofcwatercincthecbody.cEpinephrineccausescin
creasescincheartcratecandcforcecofccontraction.cIncreasedccortisolcsecretionciscduectocACTH.cBre
akdowncofcfatciscduectocglucagon.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
6. DuringcwhichcphasecofctheccellccycleciscDNAcsynthesized?
a. G1
b. S
c. G2
d. M
PATHOPHYSIOLOGY
The Biologic Basis For Disease InAdults
c c c c c c c
And Children
c
8THEDITION BY KATHRYN L.MCC
c c c c c
ANCE
,McCance:cPathophysiology:cThecBiologiccBasiscforcDiseasecincAdultscandcChildrenc(8thcEdition)cTESTcBANK
CONTENTS:
Chapterc01:cCellularcBiology
Chapterc02:cAlteredcCellularcandcTissuecBiology:cEnvironmentalcAgents
Chapterc03:cThecCellularcEnvironment:cFluidscandcElectrolytes,cAcidscandcBases
Chapterc04:cGenescandcGeneticcDiseases
Chapterc05:cGenes,cEnvironment-Lifestyle,candcCommoncDiseases
Chapterc06:cEpigeneticscandcDisease
Chapterc07:cInnatecImmunity:cInflammationcandcWoundcHealing
Chapterc08:cAdaptivecImmunity
Chapterc09:cAlterationscincImmunitycandcInflammation
Chapterc10:cInfection
Chapterc11:cStresscandcDisease
Chapterc12:cCancercBiology
Chapterc13:cCancercEpidemiology
Chapterc14:cCancercincChildren
Chapterc15:cStructurecandcFunctioncofcthecNeurologiccSystem
Chapterc16:cPain,cTemperaturecRegulation,cSleep,candcSensorycFunction
Chapterc17:cAlterationscincCognitivecSystems,cCerebralcHemodynamics,candcMotorcFunction
Chapterc18:cDisorderscofcthecCentralcandcPeripheralcNervouscSystemscandcthecNeuromuscularcJunction
Chapterc19:cNeurobiologycofcSchizophrenia,cMoodcDisorders,candcAnxietycDisorders
Chapterc20:cAlterationscofcNeurologiccFunctioncincChildren
Chapterc21:cMechanismscofcHormonalcRegulation
Chapterc22:cAlterationscofcHormonalcRegulation
Chapterc23:cObesitycandcDisorderscofcNutrition
Chapterc24:cStructurecandcFunctioncofcthecReproductivecSystems
Chapterc25:cAlterationscofcthecFemalecReproductivecSystem
Chapterc26:cAlterationscofcthecMalecReproductivecSystem
Chapterc27:cSexuallycTransmittedcInfections
Chapterc28:cStructurecandcFunctioncofcthecHematologiccSystem
Chapterc29:cAlterationscofcErythrocytes,cPlatelets,candcHemostaticcFunction
Chapterc30:cAlterationscofcLeukocytecandcLymphoidcFunction
Chapterc31:cAlterationscofcHematologiccFunctioncincChildren
Chapterc32:cStructurecandcFunctioncofcthecCardiovascularcandcLymphaticcSystems
Chapterc33:cAlterationscofcCardiovascularcFunction
Chapterc34:cAlterationscofcCardiovascularcFunctioncincChildren
Chapterc35:cStructurecandcFunctioncofcthecPulmonarycSystem
Chapterc36:cAlterationscofcPulmonarycFunction
Chapterc37:cAlterationscofcPulmonarycFunctioncincChildren
Chapterc38:cStructurecandcFunctioncofcthecRenalcandcUrologiccSystems
Chapterc39:cAlterationscofcRenalcandcUrinarycTractcFunction
Chapterc40:cAlterationscofcRenalcandcUrinarycTractcFunctioncincChildren
Chapterc41:cStructurecandcFunctioncofcthecDigestivecSystem
Chapterc42:cAlterationscofcDigestivecFunction
Chapterc43:cAlterationscofcDigestivecFunctioncincChildren
Chapterc44:cStructurecandcFunctioncofcthecMusculoskeletalcSystem
Chapterc45:cAlterationscofcMusculoskeletalcFunction
Chapterc46:cAlterationscofcMusculoskeletalcFunctioncincChildren
Chapterc47:cStructure,cFunction,candcDisorderscofcthecIntegument
Chapterc48:cAlterationscofcthecIntegumentcincChildren
Chapterc49:cShock,cMultiplecOrgancDysfunctioncSyndrome,candcBurnscincAdults
Chapterc50:cShock,cMultiplecOrgancDysfunctioncSyndrome,candcBurnscincChildren
, McCance:cPathophysiology:cThecBiologiccBasiscforcDiseasecincAdultscandcChildrenc(8thcEdition)cTESTcBANK
Partc1:cCENTRALcCONCEPTScOFcPATHOPHYSIOLOGY:cCELLScANDcTISSUESc
UnitcI:cTHEcCELL
CHAPTERc01:cCELLULARcBIOLOGY
MULTIPLEcCHOICE
1. Whichcstatementcbestcdescribesctheccellularcfunctioncofcmetaboliccabsorption?
a. Cellsccancproducecproteins.
b. Cellsccancsecretecdigestivecenzymes.
c. Cellsccanctakecincandcusecnutrients.
d. Cellsccancsynthesizecfats.
ANS:c C
Incmetaboliccabsorption,callccellsctakecincandcusecnutrientscandcothercsubstancescfromctheircsurroun
dings.cThecremainingcoptionscarecnotcinclusivecinctheircdescriptionscofccellularcmetaboliccabsorptio
n.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
2. Whereciscmostcofcaccell’scgeneticcinformation,cincludingcRNAcandcDNA,ccontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:c C
Thecnucleusccontainscthecnucleolus,cacsmallcdensecstructureccomposedclargelycofcRNA,cmostcofcth
eccellularcDNA,candcthecDNA-
bindingcproteins,csuchcascthechistones,cwhichcregulatecitscactivity.cThecmitochondriacarecresponsi
blecforccellularcrespirationcandcenergycproduction.
Ribosomes’cchiefcfunctioncisctocprovidecsitescforccellularcproteincsynthesis.cLysosomescfunctioncas
cthecintracellularcdigestivecsystem.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
3. Whichccomponentcofctheccellcproduceschydrogencperoxidec(H2O2)cbycusingcoxygenctocremovech
ydrogencatomscfromcspecificcsubstratescincancoxidativecreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:c B
, McCance:cPathophysiology:cThecBiologiccBasiscforcDiseasecincAdultscandcChildrenc(8thcEdition)cTESTcBANK
Peroxisomescarecsocnamedcbecausectheycusuallyccontaincenzymescthatcusecoxygenctocremovechydr
ogencatomscfromcspecificcsubstratescincancoxidativecreactioncthatcproducescH2O2,cwhichciscacpower
fulcoxidantcandcpotentiallycdestructivecifcitcaccumulatescorcescapescfromcperoxisomes.
RibosomescarecRNA-
proteinccomplexesc(nucleoproteins)cthatcarecsynthesizedcincthecnucleoluscandcsecretedcintoctheccyt
oplasmcthroughcporescincthecnuclearcenvelopeccalledcnuclearcporeccomplexes.cLysosomescarecsacl
ikecstructurescthatcoriginatecfromcthecGolgiccomplexcandccontaincmorecthanc40cdigestivecenzymesc
calledchydrolases,cwhichccatalyzecbondscincproteins,clipids,cnucleiccacids,candccarbohydrates.cAnc
endosomeciscacvesicalcthatchascbeencpinchedcoffcfromctheccellularcmembrane.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
4. Whichccellccomponentcisccapablecofccellularcautodigestioncwhencitciscreleasedcduringccellcinjury?
a. Ribosome
b. Golgiccomplex
c. Smoothcendoplasmiccreticulum
d. Lysosomes
ANS:c D
Theclysosomalcmembranecactscascacprotectivecshieldcbetweencthecpowerfulcdigestivecenzymescwit
hinctheclysosomecandctheccytoplasm,cpreventingctheircleakagecintoctheccytoplasmiccmatrix.cDisrup
tioncofcthecmembranecbycvariousctreatmentscorccellularcinjurycleadsctocacreleasecofctheclysosomalce
nzymes,cwhichccancthencreactcwithctheircspecificcsubstrates,ccausingccellularcself-
cdigestion.cThecchiefcfunctioncofcacribosomecisctocprovidecsitescforccellularcproteincsynthesis.cThecG
olgiccomplexciscacnetworkcofcflattened,csmoothcvesiclescandcmembranescoftenclocatedcnearctheccellc
nucleus.cThecsmoothcendoplasmiccreticulumciscinvolvedcincsteroidchormonecproductioncandcremov
ingctoxiccsubstancescfromctheccell.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
5. WhichccAMP-mediatedcresponseciscrelatedctocantidiureticchormone?
a. Increasedcheartcratecandcforcecofccontraction
b. Secretioncofccortisol
c. Increasedcretentioncofcwater
d. Breakdowncofcfat
ANS:c C
Antidiureticchormonecleadsctocincreasedcretentioncofcwatercincthecbody.cEpinephrineccausescin
creasescincheartcratecandcforcecofccontraction.cIncreasedccortisolcsecretionciscduectocACTH.cBre
akdowncofcfatciscduectocglucagon.
PTS:ccc 1 DIF: CognitivecLevel:cRemembering
6. DuringcwhichcphasecofctheccellccycleciscDNAcsynthesized?
a. G1
b. S
c. G2
d. M
