QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS VERIFIED GRADED A++
what is the osmotic diuretic that cannot be used if crystalized
mannitol
mannitol is a ______________________ that is not effectively metabolized, and is
excreted largely unchanged in the urine
sugar-alcohol
how does mannitol work
pulls fluids into intravascular space to be excreted by the kidneys to reduce intracranial
pressure
adrs of mannitol
fluid overload, renal failure, confusion, coma seizures
Antiplatelet drugs list
acetylsalicylic acid/ASA
clopidogrel
ticalgrelor
why is Aspirin contraindicated in peds
reyes syndrome
how much aspirin is used for pain relief (works as NSAID)
, 325mg
how much aspirin is used for CV event prevention (does not work as an NSAID,
only as antiplatelet
81mg (baby aspirin)
t or f ASA is typically enteric coated
t
salicylate toxicity possible in overdose
t
common fruit that have "natural aspirins" (salicylates)
cherries or willow bark
which has lower bleeding rates? anticoagulants or antiplatelets
antiplatelet
what happens when u use anticoagulants with antiplatelets
sysnergistically - heightens bleeding risk
thrombolytic drugs list
alteplase
how do thrombolytics work
Directly or indirectly aid conversion of plasminogen to plasmin. Plasmin then cleaves
thrombin and fibrin clots.
what drug has the biggest bleeding risk
thrombolytics
when are thrombolytic drugs indicated