SOLUTIONS VERIFIED LATEST UPDATE GRADED A++
Hypertriglyceridemia can cause ______
Pancreatitis
What are the best medications to lower elevated trigs
Fibrates, Niacin
What is the goal of lipid lowering agents
Plaque stabilization
Reversal of endothelial dysfunction
Thrombogenicity
Atherosclerosis regression
What are the RF associated in determining when to start statin therapy
Gender, age, race, smoking, BP, blood cholesterol levels, DM
At what age should statins be initiated for a pt with DM or cardiovascular dz
40-75yr
When would it be acceptable to start statin therapy in a pt who is 21 yrs
If LDL > or = 190 mg/dL
Best meds to lower elevated LDL
Statins
Bile acid sequestrants
Best meds to lower elevated HDL
, Niacin
Fibrates
Best lipid lowering medication for a pt with DM2
Statins
Fibrates
AE of Statins
Myositis
Rhabdomyolysis
Hepatitis
AE of Niacin
Flushing
Hyperglycemia
GI upset
AE of Fibrates
Gallstones
GI sx
AE of Bile acid sequestrants
GI distress, constipation, decreased absorption of other drugs
Which lipid lowering meds are safe in pregnancy
Bile acid sequestrants
MOA of ezetimibe
Inhibits intestinal cholesterol absorption
What is used in combo with statins for hypertrigs