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BLD 402 - EXAM 1 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++

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BLD 402 - EXAM 1 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ Physiological factors involved in the control of total body water: Protein function, cell size/shape. Intracellular Water: 40% of body weight Extracellular Water: 20% (5% in plasma, 15% in interstitial fluid). Percentage of body weight that is water? 60% of total body weight. Hormonal Control of Body Water: Hypothalamic Antidiuretic Hormone (ADH, vasopressin). Physiologic Control of Body Water: Thirst, Renal Water Reabsorption Regulation of Release from Hypothalamus by Sensing - Increased EC Osmolarity: Receptors in hypothalamus triggered. Regulation of Release from Hypothalamus by Sensing - Decreased Vascular Volume: Signals from receptors to CNS to Hypothalamus. Where are Receptors Related to Body Water Found in the Body? Receptors are found in the atria of the heart, inferior vena cava, pulmonary veins, aorta and carotid arteries. Baroreceptors sense stretches, and CNS regulates heart rate and vessel constriction. Renin: Protease released from the kidneys. Regulators of release include decreased renal perfusion pressure, sympathetic nerve stimulation (response to epinephrine). What carries out the conversion of angiotensinogen to angiotensin I? Renin Angiotensin Converting Enzyme: Released from capillaries (especially lung) and converts angiotensin I to angiotensin II. Angiotensin II: Works to constrict blood vessels, trigger aldosterone release from adrenal cortex, trigger thirst, trigger ADH secretion, and increase Na+ reabsorption in the kidney (causing retention of body water). Aldosterone: A steroid hormone released from the adrenal cortex that works to increase the Na+/K+ exchange (more Na retained, more K excreted) and increases water reabsorption in kidney. Natriuretic Peptides: Work to oppose the effects of renin-angiotensin system. They relax blood vessels by suppressing SNS activity, increase vascular permeability (more Na out, more water in, more water lost by kidneys), suppress renin-angiotensin system, inhibit salt appetite, water intake, and inhibit secretion of ADH. What are Natriuretic Peptides released in response to? Hypervolemia. What is the conductor and what is the non-conductor in bioelectric impedance: Water = conductor; fat = non-conductor. Indicator Dilution Method: Administrate a known amount of a compound, and then recover specimen. Calculate the water volume from the concentration of the specimen and administered amount. Indicator Dilution Method - Plasma Volume Calculation: Plasma volume = (total blood volume/[1-hematocrit]) Indicator Dilution Method - Intracellular Water Calculation: Intracellular Water = total water - extracellular water. Complications of Dehydration: Heat injury (denatures protein; affects body function),

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BLD 402 - EXAM 1 QUESTIONS AND ANSWERS WITH

COMPLETE SOLUTIONS GRADED A++


Physiological factors involved in the control of total body water:

Protein function, cell size/shape.

Intracellular Water:

40% of body weight

Extracellular Water:

20% (5% in plasma, 15% in interstitial fluid).

Percentage of body weight that is water?

60% of total body weight.

Hormonal Control of Body Water:

Hypothalamic Antidiuretic Hormone (ADH, vasopressin).

Physiologic Control of Body Water:

Thirst, Renal Water Reabsorption

Regulation of Release from Hypothalamus by Sensing - Increased EC Osmolarity:

Receptors in hypothalamus triggered.

Regulation of Release from Hypothalamus by Sensing - Decreased Vascular

Volume:

Signals from receptors to CNS to Hypothalamus.

Where are Receptors Related to Body Water Found in the Body?

, Receptors are found in the atria of the heart, inferior vena cava, pulmonary veins, aorta

and carotid arteries. Baroreceptors sense stretches, and CNS regulates heart rate and

vessel constriction.

Renin:

Protease released from the kidneys. Regulators of release include decreased renal

perfusion pressure, sympathetic nerve stimulation (response to epinephrine).

What carries out the conversion of angiotensinogen to angiotensin I?

Renin

Angiotensin Converting Enzyme:

Released from capillaries (especially lung) and converts angiotensin I to angiotensin II.

Angiotensin II:

Works to constrict blood vessels, trigger aldosterone release from adrenal cortex,

trigger thirst, trigger ADH secretion, and increase Na+ reabsorption in the kidney

(causing retention of body water).

Aldosterone:

A steroid hormone released from the adrenal cortex that works to increase the Na+/K+

exchange (more Na retained, more K excreted) and increases water reabsorption in

kidney.

Natriuretic Peptides:

Work to oppose the effects of renin-angiotensin system. They relax blood vessels by

suppressing SNS activity, increase vascular permeability (more Na out, more water in,

more water lost by kidneys), suppress renin-angiotensin system, inhibit salt appetite,

water intake, and inhibit secretion of ADH.

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