BLD 402 PANCREAS EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS GRADED A++ LATEST
UPDATE
Excretion control
1. Ampulla: common bile duct and pancreatic duct join here
2. Sphincter: The muscle closes/opens the ampulla
Regulation of exocrine enzymes activity
1. Activation of digestive enzyme: most enzymes are secreted as inactive form to
prevent digesting pancreas itself= activated in duodenum by activating enzyme
2. pH: enzymes are not active until pH becomes adequate by HCOs- (neutralizes H+)
3. Stimulation of release:
a. Hormones (cholecystokinin, secretin, gastrin)
b. Type of food/drink
c. Vagal nerve
d. Feedback by protease
Digestive enzymes
There are at least 22 enzymes and 15 are proteases
Amylase: Hydrolysis of alpha-1,4-glycosidic bonds in starch (amylose, amylopectin) and
glycogen. Requires Ca2+ for rxn
Lipase: Hydrolysis of glycerides
WITH COMPLETE SOLUTIONS GRADED A++ LATEST
UPDATE
Excretion control
1. Ampulla: common bile duct and pancreatic duct join here
2. Sphincter: The muscle closes/opens the ampulla
Regulation of exocrine enzymes activity
1. Activation of digestive enzyme: most enzymes are secreted as inactive form to
prevent digesting pancreas itself= activated in duodenum by activating enzyme
2. pH: enzymes are not active until pH becomes adequate by HCOs- (neutralizes H+)
3. Stimulation of release:
a. Hormones (cholecystokinin, secretin, gastrin)
b. Type of food/drink
c. Vagal nerve
d. Feedback by protease
Digestive enzymes
There are at least 22 enzymes and 15 are proteases
Amylase: Hydrolysis of alpha-1,4-glycosidic bonds in starch (amylose, amylopectin) and
glycogen. Requires Ca2+ for rxn
Lipase: Hydrolysis of glycerides
