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BLD 402, EXAM 4 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++

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BLD 402, EXAM 4 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ Which of the following is true about estriol (E3)? Maternal serum concentration of is dependent on both placental and fetal metabolism. A woman who is 20 weeks pregnant has produced the following lab test results: serum hCG normal, serum progesterone normal, E3 not detected. These three tests had been normal until now. Of the following conditions, which would best fit with this data set? recent death of fetus in-utero Which test most correlates with the severity of HDN (hemolytic disease of newborn)? amniotic fluid bilirubin level Which of the following is true about L/S ratio? L/S ratio ≥ 2.0 means the fetus lung is mature. What is the cause of respiratory distress syndrome in newborns? insufficient production of surfactant Cerebrospinal fluid (CSF) is formed at where? Choroid plexus What is the main role of a clinical lab for psychiatric disorders? therapeutic drug monitoring Look at this CSF test results: decreased glucose, increased proteins, increased lactate, increased WBC (mostly neutrophils). What is the most likely cause? Bacterial meningitis The diagnosis of multiple sclerosis is often based on what? The presence of oligoclonal bands by CSF electrophoresis. What is hCG? a crucial pregnancy hormone produced by the placenta after implantation What are the functions of hCG? -stimulates the corpus luteum to produce progesterone and estrogen, which are essential for maintaining pregnancy -also supports fetal growth and development Menopause effect on hCG in a rare cases, the pituitary gland may start producing hCG during menopause, leading to elevated levels. How is hCG related to certain pathological conditions? -Choriocarcinoma and testicular cancer: tumors producing high levels of hCG -Ectopic Pregnancy: Lower levels of hCG may be seen in ectopic pregnancies compared to normal pregnancies -Hydatidiform Mole: type of molar pregnancy characterized by abnormal growth of placental tissue and high levels of hCG What are the different types of molar pregnancy? -Complete Molar Pregnancy: No fetal tissue is present -Partial Molar Pregnancy: Some fetal tissue is present but abnormal -boh risk producing a choriocarcinoma progesterone A hormone produced by the ovaries and placenta -used to monitor pregnancy, menstrual cycles, and infertility Cystic Fibrosis (CF) Epithelial cell transmembrane regulator defect ↓ Cl- → ↓ NaCl → ↓ H2O → high mucus viscosity Congested lungs, male infertility, pancreatic insufficiency, and abnormal bile flow Newborn screening: serum immunoreactive trypsin (IRT) with high diagnostic sensitivity and low specificity if positive: sweat and genetic testing ↑ Cl- in sweat E2

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BLD 402, EXAM 4 QUESTIONS AND ANSWERS WITH

COMPLETE SOLUTIONS GRADED A++


Which of the following is true about estriol (E3)?

Maternal serum concentration of is dependent on both placental and fetal metabolism.

A woman who is 20 weeks pregnant has produced the following lab test results:

serum hCG normal, serum progesterone normal, E3 not detected. These three

tests had been normal until now. Of the following conditions, which would best fit

with this data set?

recent death of fetus in-utero

Which test most correlates with the severity of HDN (hemolytic disease of

newborn)?

amniotic fluid bilirubin level

Which of the following is true about L/S ratio?

L/S ratio ≥ 2.0 means the fetus lung is mature.

What is the cause of respiratory distress syndrome in newborns?

insufficient production of surfactant

Cerebrospinal fluid (CSF) is formed at where?

Choroid plexus

What is the main role of a clinical lab for psychiatric disorders?

therapeutic drug monitoring

, Look at this CSF test results: decreased glucose, increased proteins, increased

lactate, increased WBC (mostly neutrophils).

What is the most likely cause?

Bacterial meningitis

The diagnosis of multiple sclerosis is often based on what?

The presence of oligoclonal bands by CSF electrophoresis.

What is hCG?

a crucial pregnancy hormone produced by the placenta after implantation

What are the functions of hCG?

-stimulates the corpus luteum to produce progesterone and estrogen, which are

essential for maintaining pregnancy

-also supports fetal growth and development

Menopause effect on hCG

in a rare cases, the pituitary gland may start producing hCG during menopause, leading

to elevated levels.

How is hCG related to certain pathological conditions?

-Choriocarcinoma and testicular cancer: tumors producing high levels of hCG

-Ectopic Pregnancy: Lower levels of hCG may be seen in ectopic pregnancies

compared to normal pregnancies

-Hydatidiform Mole: type of molar pregnancy characterized by abnormal growth of

placental tissue and high levels of hCG

What are the different types of molar pregnancy?

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