BLD 402: SYNOVIAL FLUID EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS GRADED A++
What are synoviocytes?
-Inner part of the synovial membrane
What are the 2 types of synoviocytes?
-Phagocytic cell: produces degradative enzymes
-Hyaluronate synthesizing cell: produces hyaluronate
Where is the connective tissue?
Outer side of synoviocytes layer, inside synovial membrane
What components does the connective tissue contain?
-Blood vessels
-Lymphatic system
-Nerves
What are the functions of synovial fluid?
-Lubricant
-Nutrient for articular cartilage (because no blood vessel here)
What is the composition of synovial fluid?
-Ultrafiltrate of plasma across synovial membrane: only small molecules at normal
condition (NO FIBRINOGEN)
-Secretion of synoviocytes: hyaluronate
Which specimen should be collected at the same time as synovial fluid?
, Blood specimen
What method is used for synovial fluid collection?
Athrocentesis: aspiration with needle and syringe
What container should be used for synovial fluid collection?
-Sterile tube for microbial test (3-10mL)
-Sodium heparin tube for microscopic test (2-5 mL) (DO NOT use EDTA, forms crystals)
-Plain tube for chemical/immunological tests
Why are synovial fluid specimen STAT?
-Chemical composition would change over time
-Detection of microbe decreases
-Cells undergo lysis
-Crystals may form or dissolve
What are the characteristics of normal synovial fluid?
-No color or pale yellow
- <200 leukocytes
- <10 glucose difference from blood
What are the characteristics of Group I (non-inflammatory) synovial fluid?
-Yellow
- <3000 leukocytes
- <25 glucose difference from blood
What are the characteristics of Group II (inflammatory) synovial fluid?
-Yellow-white
-Low viscosiity
WITH COMPLETE SOLUTIONS GRADED A++
What are synoviocytes?
-Inner part of the synovial membrane
What are the 2 types of synoviocytes?
-Phagocytic cell: produces degradative enzymes
-Hyaluronate synthesizing cell: produces hyaluronate
Where is the connective tissue?
Outer side of synoviocytes layer, inside synovial membrane
What components does the connective tissue contain?
-Blood vessels
-Lymphatic system
-Nerves
What are the functions of synovial fluid?
-Lubricant
-Nutrient for articular cartilage (because no blood vessel here)
What is the composition of synovial fluid?
-Ultrafiltrate of plasma across synovial membrane: only small molecules at normal
condition (NO FIBRINOGEN)
-Secretion of synoviocytes: hyaluronate
Which specimen should be collected at the same time as synovial fluid?
, Blood specimen
What method is used for synovial fluid collection?
Athrocentesis: aspiration with needle and syringe
What container should be used for synovial fluid collection?
-Sterile tube for microbial test (3-10mL)
-Sodium heparin tube for microscopic test (2-5 mL) (DO NOT use EDTA, forms crystals)
-Plain tube for chemical/immunological tests
Why are synovial fluid specimen STAT?
-Chemical composition would change over time
-Detection of microbe decreases
-Cells undergo lysis
-Crystals may form or dissolve
What are the characteristics of normal synovial fluid?
-No color or pale yellow
- <200 leukocytes
- <10 glucose difference from blood
What are the characteristics of Group I (non-inflammatory) synovial fluid?
-Yellow
- <3000 leukocytes
- <25 glucose difference from blood
What are the characteristics of Group II (inflammatory) synovial fluid?
-Yellow-white
-Low viscosiity
