COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE
environmental disease
Disorders caused by exposure to chemicals or physical agents like radiation in the
ambient, workplace, or personal environments
toxicology
The science of poisons; distributions, effects, mechanisms, physical agents
dosage
point at which a chemical becomes carcinogenic (kg/body weight)
List and explain the possible impacts of climate change on human health.
Rising temperatures lead to more extreme weather lead to rising sea levels lead to
increased CO2 levels.
Rising temps. lead to (Extreme heat) Heat-related illness and death, cardiovascular
failure, (severe weather) injuries, fatalities, and mental health impacts.
More extreme weather leads to (air pollution) asthma, cardiovascular disease, (changes
in Vector Ecology) Malaria, dengue, encephalitis, hantavirus, Rift Valley fever, Lyme
disease, chikungunya, West Nile Virus.
Rising sea levels lead to (increasing allergens) respiratory allergies, asthma, (Water
quality impacts) Cholera, cryptosporidiosis, campylobacter, leptospirosis, harmful algal
blooms.
, Increasing CO2 levels lead to (Environmental degradation) Forced migration, civil
conflict, mental health impacts.
Discuss the possible routes of entry/exposure of environmental toxins
Inhalation Ingestion Skin absorption
List the most important enzymatic system for dealing with xenobiotics
cytochrome P-450 system
Discuss the types and sources of air pollution and their physical effects on
human health
Air pollution is particulates, microbes, and chemicals both indoor and outdoor. Ozone,
sulfur dioxide, nitrogen dioxide, lead, carbon monoxide are outdoor.
Indoor:
- Smoke: indoor burning for cooking and heating, contributes to nitrogen oxides,
particulate matter acts as irritants
- Radon: radioactive gas from uranium in the ground, contributes to lung cancer risk
- Bioaerosols: infectious microbes and allergens like pet dander, effects of infectious
respiratory diseases and asthma
Discuss the sources of and clinical symptoms of exposure to the following heavy
metals
Lead
Mercury
Arsenic
Lead in air, food, soil, flaking paint contributes to reduced heme synthesis (anemia),
edema, demyelination, necrosis of neurons, chronic damage can lead to kidney failure.