BLD204 - 2 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE

BLD204 - 2 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE wuts on the helper T cell CD3, CD4, TCR, and MHC class 1 wuts on the cytotoxic t cell CD3, CD8, TCR, and MHC class 1 wuts on the B cell BCR, MHC class 1, and MHC class 2 human immunity characteristics recognition of self and non-self, memory antigens molecules recognized as non-self, can be exogenous or endogenous innate immunity 1st rxn, not antigen specific adaptive immunity 2ns rxn, specific/powerful, can be humoral or cell mediated humoral antibody-mediated immunity cell-mediated immunity cells targeting other cells (ex. T cells) primary lymphoid tissue thymus and bone marrow secondary lymphoid tissue lymph nodes, spleen, and MALT natural killer cells cytotoxic lymphocytes, recognize loss of self-antigen how NK cells work release 1st bomb: proteins that poke holes into the diseased release 2nd bomb: proteases T cells thymus derived lymphocytes that are presented antigens by APCs where are T cells found blood, spleen, lymph node interfollicular zones CD8 cytotoxic T cells direct cell killing (apoptosis), produce cytokines, MHC class 1 presents antigens to CD8 CD4 helper T cells release cytokines that stimulate B cells to make antibodies and encourage macrophages to destroy microbes MHC stand for major histocompatibility complex HLA stands for human leukocyte antigen MHC Class 1 Present on all cells except red blood cells, signals to CD8 cells why don't RBCs express MHC class 1 no nucleus MHC class 2 only on the APCs; antigen is consumed, chewed, and presented to CD4 cells γδ T cells recognize lipid antigens and stress proteins, don't require presentation where are γδ T cells found bone marrow, circulation, spleen, MALT, and lymph node follicles how many heavy and light chains on an immunoglobulin 2 heavy and 2 light coming together to form 2 AB binding sites types of light chains kappa and lambda What holds the heavy and light chains together disulfide bonds IgG PLASMA, neutralizes toxins and opsonizes BACTERIA, can cross placenta IgM big boi, pentameter, PLASMA IgA MUCOSA, stops BACTERIA/VIRUSES from entering epithelium IgE MAST CELLS; results in release of histamine, leukotrienes; calls eosinophils; PARASITES; PLASMA