ANSWERS WITH COMPLETE SOLUTIONS GRADED
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Define the following: environmental disease, toxicology, dosage.
Environmental Disease: Disorders caused by exposure to chemicals or physical agents
like radiation in the ambient, workplace, or personal environments. Dependent on
general health, age, genes, tissue types...
Toxicology: The science of poisons.
1. Distribution
2. Effects
3. Mechanisms
4. Physical Agents
Dosage: a level of exposure to or absorption of ionizing radiation. Could also be the size
or frequency of a dose of a medicine or drug.
Discuss the possible results of exposure to environmental toxins.
Skin, Lung, GI absorption
Bloodstream transport to tissues
, Stored or excreted
Another figure on pg. 336 of course pack as well!
Discuss the sources of and clinical symptoms of exposure of Lead:
a. Lead:
Source: Contaminated Air and Food and Soil contamination, flaking paint.
Clinical Symptoms: Binds to proteins, interferes with Ca metabolism, inhibits healing of
fractures, Toxic to the nervous system, interferes with heme synthesis.
Discuss the sources of and clinical symptoms of exposure of Mercury:
b. Mercury:
Source: Fish and dental amalgams.
Clinical Symptoms: Tremor, gingivitis, bizarre behavior, birth defects from in utero
exposure.
Discuss the sources of and clinical symptoms of exposure of Arsenic:
c. Arsenic:
Source: Naturally occurring in soil and water (mining).
Clinical Symptoms: Large amounts - GI, cardio, and CNS disturbances due to
interference with oxidative phosphorylation. Chronic exposure increases risk of basal
and squamous cell carcinomas.
Define pneumoconiosis and list the etiologic agents which most commonly cause
these disorders.