BLD324 EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS GRADED A++
Megakaryocyte production of platelets is dependent upon which cytokine(s)?
thrombopoietin (TPO)
Which of the following is function of blood vessels that prevents clotting?
Heparin Sulfate
Name the region of platelet anatomy where tubulin is found
The structural zone
Which of the following platelet functions results in a shape change in platelets?
Activation
Where is von Willebrand Factor found?
On the surface of the subendothelial collagen (SEC)
Select the first step in platelet response to injury.
Adhesion
Upon Activation, platelets secrete their alpha granule contents via:
the surface canalicular system
which platelet receptors bind 1) vWF and 2) Fibrinogen, respectively?
1)glycoprotein Ib, 2)glycoprotein IIa/IIIa
Clot retraction occurs when
aggregated platelets connected by Fibrinogen contract
,A STAT APTT is ordered. A blue top, Na citrate tube is submitted to the lab
partially full. What does the lab do next?
Reject the sample and request a new one
A STAT PT is ordered. A blue top, Na citrate sample is properly drawn on a
severely dehydrated patient. Select the correct statement.
The sample was collected properly. Reject the sample due to the dehydration.
A STAT aPTT is ordered. A blue top, Na citrate sample is properly drawn on a
patient receiving heparin. Select the correct statement.
The sample was collected properly. Run the test and report the result
What is the source of PPL in the coagulation cascade?
Platelet membrane
Select the correct composition of the prothrombinase complex.
PPL, Calcium, Factor Xa, Factor V
Why are coagulation tests called functional assays? Select the bEST answer.
Clot formation testing measures the separate function of the Tissue Factor and Contract
Pathways
Which of the following pairs of coagulation factors are considered cofactors?
Factor V and VIII
vonWillebrand's Factor binds platelets to collagen through which receptor?
GPIb
Complete the principle of the reaction of platelet aggregation studies with the
BEST answer.
Principple: platelet rich plasma is added to a cuvette, and agonist is added,
, the decrease in light transmitted is proportional to increased activation, aggregation, or
agglutination
Which of the following platelet aggregation curves demonstrates agglutination?
D
Upon Activation, platelets secrete their alpha granule contents via:
the surface canclicular system
The BODY's iron levels are ultimately controlled by-
activity of iron transport out of the enterocyte
Which WBC is responsible for defense against parasites?
Eosinophils
Why does the Ret-HE change before HGB values in iron deficiency anemia?
The Ret-He assay measures the iron available for hematopoiesis
Which of the following RBC membrane proteins provides a flexible but strong
cytoskeleton?
Spectrin
Which of the following proteins allows platelets to maintain their discoid shape?
Myosin
Which of the following coagulation factors must form a complex with other
cofactors to function?
Factor X
The platelet aggregation test shows no secondary wave. Select the correct
platelet issue.
Aggregation with high calcium levels
COMPLETE SOLUTIONS GRADED A++
Megakaryocyte production of platelets is dependent upon which cytokine(s)?
thrombopoietin (TPO)
Which of the following is function of blood vessels that prevents clotting?
Heparin Sulfate
Name the region of platelet anatomy where tubulin is found
The structural zone
Which of the following platelet functions results in a shape change in platelets?
Activation
Where is von Willebrand Factor found?
On the surface of the subendothelial collagen (SEC)
Select the first step in platelet response to injury.
Adhesion
Upon Activation, platelets secrete their alpha granule contents via:
the surface canalicular system
which platelet receptors bind 1) vWF and 2) Fibrinogen, respectively?
1)glycoprotein Ib, 2)glycoprotein IIa/IIIa
Clot retraction occurs when
aggregated platelets connected by Fibrinogen contract
,A STAT APTT is ordered. A blue top, Na citrate tube is submitted to the lab
partially full. What does the lab do next?
Reject the sample and request a new one
A STAT PT is ordered. A blue top, Na citrate sample is properly drawn on a
severely dehydrated patient. Select the correct statement.
The sample was collected properly. Reject the sample due to the dehydration.
A STAT aPTT is ordered. A blue top, Na citrate sample is properly drawn on a
patient receiving heparin. Select the correct statement.
The sample was collected properly. Run the test and report the result
What is the source of PPL in the coagulation cascade?
Platelet membrane
Select the correct composition of the prothrombinase complex.
PPL, Calcium, Factor Xa, Factor V
Why are coagulation tests called functional assays? Select the bEST answer.
Clot formation testing measures the separate function of the Tissue Factor and Contract
Pathways
Which of the following pairs of coagulation factors are considered cofactors?
Factor V and VIII
vonWillebrand's Factor binds platelets to collagen through which receptor?
GPIb
Complete the principle of the reaction of platelet aggregation studies with the
BEST answer.
Principple: platelet rich plasma is added to a cuvette, and agonist is added,
, the decrease in light transmitted is proportional to increased activation, aggregation, or
agglutination
Which of the following platelet aggregation curves demonstrates agglutination?
D
Upon Activation, platelets secrete their alpha granule contents via:
the surface canclicular system
The BODY's iron levels are ultimately controlled by-
activity of iron transport out of the enterocyte
Which WBC is responsible for defense against parasites?
Eosinophils
Why does the Ret-HE change before HGB values in iron deficiency anemia?
The Ret-He assay measures the iron available for hematopoiesis
Which of the following RBC membrane proteins provides a flexible but strong
cytoskeleton?
Spectrin
Which of the following proteins allows platelets to maintain their discoid shape?
Myosin
Which of the following coagulation factors must form a complex with other
cofactors to function?
Factor X
The platelet aggregation test shows no secondary wave. Select the correct
platelet issue.
Aggregation with high calcium levels
