BLD 324 FINAL EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE
GRADED A++
By the end of the 8th month of gestation, what is the primary organ site of
hematopoiesis?
Bone Marrow
For a fetus of four months, what contributes the most to the hematopoietic
process?
Liver
Hemoglobin A can NOT be detected during which phase of hematopoiesis
Mesoblastic
Active hematopoietic tissue can NOT be found in which of the following bones of
a 25 year old male
Femur
What cells are a product of CFU-GEMM
eosinophil
monocyte
neutrophil
erythrocyte
,An immunophenotypic analysis using flow cytometry identifies a group of
progenitor cells that express CD10 and CD38. Those cells will most likely develop
into which of the following cells
T Cell
Which of the following is the most mature normoblast?
Rubiblast, basophilic normoblast, pronormoblast, proerythroblast, orthocromic
erythroblast
orthochromic erythroblast
How may basophilic normoblasts can develop from one pronormoblast
2
What precursor is unable to divide
orthochromic normoblast
What is RBC Mass
erythrocytes in circulation
What enzyme catalyzes the production of pentose phosphate from glucose 6
phosphate
Glucose 6 phosphate dehydrogenase
What is the primary product of the hexose monophosphate pathway
NADPH and reduced glutathione
What is involved in the pathway protecting the RBC membrane from oxidizing
agents
,NADP+
Glucose 6 Phosphate
Reduced Glutathione
Which of the following does NOT contribute to RBC deformability?
-Hemoglobin Concentration of 45%
- Cytoplasmic viscosity
- Membrane elasticity
- excess surface area
Hemoglobin concentration of 45%
What transports water into the cell based on internal osmotic changes
Aquaporin
The predominant hemoglobin of a newborn at birth contains what polypeptide
chains
alpha and gamma
What globin genes are not expressed in adults
epsilon and zeta
The fetus achieves adequate tissue oxygenation by what mechanism
increased hemoglobin concentration
A 25-year-old man was rescued from a car trapped in the snow. The engine was
running when he was found. The man was in coma and exhibited cherry-red color
on his cheek. He had increased level of which type of hemoglobin?
Carboxyhemoglobin
, A 27-year-old man develops cyanosis after drinking a lot of water from a river
while hiking in the mountains. The water from the river of the area is known for
high level of nitrites. He has increased level of which type of hemoglobin?
Methemoglobin
What cell type contains both acidic and basic granules
neutrophils
What cells are developed from the common myeloid progenitor
macrophage
basophil
megakaryocyte
erythrocyte
During what stage of neutrophil development does the production of primary
granules cease and secondary granules appear
Myelocyte
What cell makes both tertiary and secretory neutrophil granules
Band
Normal ration between a circulation neutrophil pool and a marginal neutrophil
pool
1:1
What best describes the composition of neutrophil extracellular traps
Chains of nucleosomes that have enzymes capable of killing
What cell is able to destroy helminths and prevent reinfection
eosinophil
COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE
GRADED A++
By the end of the 8th month of gestation, what is the primary organ site of
hematopoiesis?
Bone Marrow
For a fetus of four months, what contributes the most to the hematopoietic
process?
Liver
Hemoglobin A can NOT be detected during which phase of hematopoiesis
Mesoblastic
Active hematopoietic tissue can NOT be found in which of the following bones of
a 25 year old male
Femur
What cells are a product of CFU-GEMM
eosinophil
monocyte
neutrophil
erythrocyte
,An immunophenotypic analysis using flow cytometry identifies a group of
progenitor cells that express CD10 and CD38. Those cells will most likely develop
into which of the following cells
T Cell
Which of the following is the most mature normoblast?
Rubiblast, basophilic normoblast, pronormoblast, proerythroblast, orthocromic
erythroblast
orthochromic erythroblast
How may basophilic normoblasts can develop from one pronormoblast
2
What precursor is unable to divide
orthochromic normoblast
What is RBC Mass
erythrocytes in circulation
What enzyme catalyzes the production of pentose phosphate from glucose 6
phosphate
Glucose 6 phosphate dehydrogenase
What is the primary product of the hexose monophosphate pathway
NADPH and reduced glutathione
What is involved in the pathway protecting the RBC membrane from oxidizing
agents
,NADP+
Glucose 6 Phosphate
Reduced Glutathione
Which of the following does NOT contribute to RBC deformability?
-Hemoglobin Concentration of 45%
- Cytoplasmic viscosity
- Membrane elasticity
- excess surface area
Hemoglobin concentration of 45%
What transports water into the cell based on internal osmotic changes
Aquaporin
The predominant hemoglobin of a newborn at birth contains what polypeptide
chains
alpha and gamma
What globin genes are not expressed in adults
epsilon and zeta
The fetus achieves adequate tissue oxygenation by what mechanism
increased hemoglobin concentration
A 25-year-old man was rescued from a car trapped in the snow. The engine was
running when he was found. The man was in coma and exhibited cherry-red color
on his cheek. He had increased level of which type of hemoglobin?
Carboxyhemoglobin
, A 27-year-old man develops cyanosis after drinking a lot of water from a river
while hiking in the mountains. The water from the river of the area is known for
high level of nitrites. He has increased level of which type of hemoglobin?
Methemoglobin
What cell type contains both acidic and basic granules
neutrophils
What cells are developed from the common myeloid progenitor
macrophage
basophil
megakaryocyte
erythrocyte
During what stage of neutrophil development does the production of primary
granules cease and secondary granules appear
Myelocyte
What cell makes both tertiary and secretory neutrophil granules
Band
Normal ration between a circulation neutrophil pool and a marginal neutrophil
pool
1:1
What best describes the composition of neutrophil extracellular traps
Chains of nucleosomes that have enzymes capable of killing
What cell is able to destroy helminths and prevent reinfection
eosinophil
