Understanding Pathophysiology 7th edition by Huether, McCance Test Bank Lat
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
Understanding Pathophysiology 7th edition by Huether, McCance Test Bank
j j j j j j j j
Chapterj1.jCellularjBiology
MULTIPLEjCHOICE
1. Ajstudentjisjobservingjajcelljunderjthejmicroscope.jItjisjobservedjtojhavejsupercoiledjDNAjwithj
histones.jWhichjofjthejfollowingjwouldjalsojbejobservedjbyjthejstudent?
a. Ajsinglejcircularjchromosome
b. Ajnucleus
c. Free-floatingjnuclearjmaterial
d. Nojorganelles
ANS:jB
Thejcelljdescribedjisjajeukaryoticjcell,jsojitjhasjhistonesjandjajsupercoiledjDNAjwithinjitsjnucleus;jth
us,jthejnucleusjshouldjbejobserved.
Ajsinglejcircularjchromosomejisjcharacteristicjofjprokaryoticjcells,jwhichjdojnotjhavejhistones.
Free-floatingjnuclearjmaterialjdescribesjajprokaryoticjcell,jwhichjwouldjnotjhavejajdistinctjnucleus.
Eukaryoticjcellsjhavejmembranejboundedjcellularjcomponentsjcalledjorganelles.jNojorganellesjdes
cribesjajprokaryoticjcell.
2. Ajnursejisjinstructingjthejstaffjaboutjcellularjfunctions.jWhichjcellularjfunctionjisjthejnursejdesc
ribingjwhenjanjisolatedjcelljabsorbsjoxygenjandjusesjitjtojtransformjnutrientsjtojenergy?
a. Metabolicjabsorption
b. Communication
c. Secretion
d. Respiration
,Understanding Pathophysiology 7th edition by Huether, McCance Test Bank Lat
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
ANS:jD
Thejabilityjofjthejcelljtojabsorbjoxygenjrefersjtojthejcellsjfunctionjofjrespiration.
Thejabilityjofjthejcelljtojfunctionjwithinjajsocietyjofjcellsjrefersjtojitsjfunctionjofjcommunication.
Thejabilityjofjthejcelljtojtakejinjnutrientsjrefersjtojthejcellsjfunctionjofjmetabolicjabsorption.
Thejabilityjofjthejcelljtojsynthesizejnewjsubstancesjandjsecretejthesejelsewherejrefersjtojthejcellsjfunctionj
ofjsecretion.
3. AjeukaryoticjcelljisjundergoingjDNAjreplication.jInjwhichjregionjofjthejcelljwouldjmostjofjthejg
eneticjinformationjbejcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS:jC
Thejregionjofjthejcelljthatjcontainsjgeneticjmaterial,jincludingjajlargejamountjofjribonucleicjacid,jm
ostjofjthejDNA,jandjDNA-bindingjproteins,jisjthejnucleolus.
Thejmitochondriajisjthejsitejofjcellularjrespiration.
Thejribosomesjarejinvolvedjinjmanufacturingjofjproteinsjwithinjthejcell.
Thejnucleusjcontainsjthejnucleolus,jandjitjisjthejnucleolusjthatjcontainsjgeneticjmaterial.
4. Thejfluidjmosaicjmodeljforjbiologicjmembranesjdescribesjmembranejbehavior.jAccordingjtojthisj
model,jwhichjofjthejfollowingjfloatjsinglyjorjasjaggregatesjinjthejfluidjlipidjbilayer?
a. Peripheraljmembranejproteins
b. Integraljmembranejproteins
,Understanding Pathophysiology 7th edition by Huether, McCance Test Bank Lat
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
c. Glycoproteins
d. Celljadhesionjmolecules
ANS:jB
Integraljmembranejproteinsjfloatjfreelyjinjthejfluidjlipidjbilayer.
Peripheraljmembranejproteinsjarejnotjembeddedjinjthejlayer,jbutjresidejatjthejsurface.jGlycoprotein
sjactjasjcelljsurfacejmarkers.
Celljadhesionjmoleculesjarejonjthejoutsidejofjthejmembranejandjallowjcellsjtojhookjtogether.
5. Whichjofjthejfollowingjcanjbindjtojplasmajmembranejreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicjlipids
d. Ligands
ANS:jD
Ligandsjarejspecificjmoleculesjthatjcanjbindjwithjreceptorsjonjthejcelljmembrane.jOxygenj
movesjbyjdiffusion;jitjdoesjnotjbindjtojreceptors.
Ribosomesjmakejproteinsjandjarejnotjinvolvedjinjbinding.jA
mphipathicjlipidsjarejajportionjofjthejcelljmembrane.
6. Ajnursejisjreviewingjajreportjfromjajpatientjwithjmetastaticjcancer.jWhatjfindingjwouldjsupp
ortjthejdiagnosisjofjmetastaticjcancer?jAlterationsjinjextracellularjmatrixjthatjinclude:
a. Decreasedjfibronectin
b. Increasedjcollagen
c. Decreasedjelastin
, Understanding Pathophysiology 7th edition by Huether, McCance Test Bank Lat
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
d. Increasedjglycoproteins
ANS:jA
Reducedjamountsjofjfibronectinjarejfoundjinjsomejtypesjofjcancerousjcells,jallowingjcancerjcellsjtojt
ravel,jorjmetastasize.
Collagenjprovidesjstrength,jandjitsjbreakdownjisjassociatedjwithjosteoarthritis,jnotjcancer.
Elastinjisjfoundjinjthejlungsjandjallowsjtissuesjtojstretch;jitjisjnotjassociatedjwithjcancerousjcells.
Decreased,jnotjincreased,jglycoproteinsjarejassociatedjwithjcancerousjcells.
7. Whichjformjofjcelljcommunicationjisjusedjtojrelatejtojotherjcellsjinjdirectjphysicaljcontact?
a. Celljjunction
b. Gapjjunction
c. Desmosomes
d. Tightjjunctions
ANS:jA
Celljjunctionsjholdjcellsjtogetherjandjpermitjmoleculesjtojpassjfromjcelljtojcell.
Gapjjunctionsjallowjcommunicationjfromjthejinsidejofjonejcelljtojthejinsidejofjanother.jDesmosome
sjarejnotjinvolvedjinjcommunication,jbutjallowjcellsjtojholdjtogether.
Tightjjunctionsjarejbarriersjthatjpreventjmovementjofjsomejsubstancesjandjleakagesjofjothers.
8. Pancreaticjbetajcellsjsecretejinsulin,jwhichjinhibitsjsecretionjofjglucagonjfromjneighboringjalp
hajcells.jThisjactionjisjanjexamplejofjwhichjofjthejfollowingjsignalingjtypes?
a. Paracrine
b. Autocrine
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
Understanding Pathophysiology 7th edition by Huether, McCance Test Bank
j j j j j j j j
Chapterj1.jCellularjBiology
MULTIPLEjCHOICE
1. Ajstudentjisjobservingjajcelljunderjthejmicroscope.jItjisjobservedjtojhavejsupercoiledjDNAjwithj
histones.jWhichjofjthejfollowingjwouldjalsojbejobservedjbyjthejstudent?
a. Ajsinglejcircularjchromosome
b. Ajnucleus
c. Free-floatingjnuclearjmaterial
d. Nojorganelles
ANS:jB
Thejcelljdescribedjisjajeukaryoticjcell,jsojitjhasjhistonesjandjajsupercoiledjDNAjwithinjitsjnucleus;jth
us,jthejnucleusjshouldjbejobserved.
Ajsinglejcircularjchromosomejisjcharacteristicjofjprokaryoticjcells,jwhichjdojnotjhavejhistones.
Free-floatingjnuclearjmaterialjdescribesjajprokaryoticjcell,jwhichjwouldjnotjhavejajdistinctjnucleus.
Eukaryoticjcellsjhavejmembranejboundedjcellularjcomponentsjcalledjorganelles.jNojorganellesjdes
cribesjajprokaryoticjcell.
2. Ajnursejisjinstructingjthejstaffjaboutjcellularjfunctions.jWhichjcellularjfunctionjisjthejnursejdesc
ribingjwhenjanjisolatedjcelljabsorbsjoxygenjandjusesjitjtojtransformjnutrientsjtojenergy?
a. Metabolicjabsorption
b. Communication
c. Secretion
d. Respiration
,Understanding Pathophysiology 7th edition by Huether, McCance Test Bank Lat
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
ANS:jD
Thejabilityjofjthejcelljtojabsorbjoxygenjrefersjtojthejcellsjfunctionjofjrespiration.
Thejabilityjofjthejcelljtojfunctionjwithinjajsocietyjofjcellsjrefersjtojitsjfunctionjofjcommunication.
Thejabilityjofjthejcelljtojtakejinjnutrientsjrefersjtojthejcellsjfunctionjofjmetabolicjabsorption.
Thejabilityjofjthejcelljtojsynthesizejnewjsubstancesjandjsecretejthesejelsewherejrefersjtojthejcellsjfunctionj
ofjsecretion.
3. AjeukaryoticjcelljisjundergoingjDNAjreplication.jInjwhichjregionjofjthejcelljwouldjmostjofjthejg
eneticjinformationjbejcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS:jC
Thejregionjofjthejcelljthatjcontainsjgeneticjmaterial,jincludingjajlargejamountjofjribonucleicjacid,jm
ostjofjthejDNA,jandjDNA-bindingjproteins,jisjthejnucleolus.
Thejmitochondriajisjthejsitejofjcellularjrespiration.
Thejribosomesjarejinvolvedjinjmanufacturingjofjproteinsjwithinjthejcell.
Thejnucleusjcontainsjthejnucleolus,jandjitjisjthejnucleolusjthatjcontainsjgeneticjmaterial.
4. Thejfluidjmosaicjmodeljforjbiologicjmembranesjdescribesjmembranejbehavior.jAccordingjtojthisj
model,jwhichjofjthejfollowingjfloatjsinglyjorjasjaggregatesjinjthejfluidjlipidjbilayer?
a. Peripheraljmembranejproteins
b. Integraljmembranejproteins
,Understanding Pathophysiology 7th edition by Huether, McCance Test Bank Lat
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
c. Glycoproteins
d. Celljadhesionjmolecules
ANS:jB
Integraljmembranejproteinsjfloatjfreelyjinjthejfluidjlipidjbilayer.
Peripheraljmembranejproteinsjarejnotjembeddedjinjthejlayer,jbutjresidejatjthejsurface.jGlycoprotein
sjactjasjcelljsurfacejmarkers.
Celljadhesionjmoleculesjarejonjthejoutsidejofjthejmembranejandjallowjcellsjtojhookjtogether.
5. Whichjofjthejfollowingjcanjbindjtojplasmajmembranejreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicjlipids
d. Ligands
ANS:jD
Ligandsjarejspecificjmoleculesjthatjcanjbindjwithjreceptorsjonjthejcelljmembrane.jOxygenj
movesjbyjdiffusion;jitjdoesjnotjbindjtojreceptors.
Ribosomesjmakejproteinsjandjarejnotjinvolvedjinjbinding.jA
mphipathicjlipidsjarejajportionjofjthejcelljmembrane.
6. Ajnursejisjreviewingjajreportjfromjajpatientjwithjmetastaticjcancer.jWhatjfindingjwouldjsupp
ortjthejdiagnosisjofjmetastaticjcancer?jAlterationsjinjextracellularjmatrixjthatjinclude:
a. Decreasedjfibronectin
b. Increasedjcollagen
c. Decreasedjelastin
, Understanding Pathophysiology 7th edition by Huether, McCance Test Bank Lat
j j j j j j j j j
est Updated Examination Study Guide 2022
j j j j j
d. Increasedjglycoproteins
ANS:jA
Reducedjamountsjofjfibronectinjarejfoundjinjsomejtypesjofjcancerousjcells,jallowingjcancerjcellsjtojt
ravel,jorjmetastasize.
Collagenjprovidesjstrength,jandjitsjbreakdownjisjassociatedjwithjosteoarthritis,jnotjcancer.
Elastinjisjfoundjinjthejlungsjandjallowsjtissuesjtojstretch;jitjisjnotjassociatedjwithjcancerousjcells.
Decreased,jnotjincreased,jglycoproteinsjarejassociatedjwithjcancerousjcells.
7. Whichjformjofjcelljcommunicationjisjusedjtojrelatejtojotherjcellsjinjdirectjphysicaljcontact?
a. Celljjunction
b. Gapjjunction
c. Desmosomes
d. Tightjjunctions
ANS:jA
Celljjunctionsjholdjcellsjtogetherjandjpermitjmoleculesjtojpassjfromjcelljtojcell.
Gapjjunctionsjallowjcommunicationjfromjthejinsidejofjonejcelljtojthejinsidejofjanother.jDesmosome
sjarejnotjinvolvedjinjcommunication,jbutjallowjcellsjtojholdjtogether.
Tightjjunctionsjarejbarriersjthatjpreventjmovementjofjsomejsubstancesjandjleakagesjofjothers.
8. Pancreaticjbetajcellsjsecretejinsulin,jwhichjinhibitsjsecretionjofjglucagonjfromjneighboringjalp
hajcells.jThisjactionjisjanjexamplejofjwhichjofjthejfollowingjsignalingjtypes?
a. Paracrine
b. Autocrine
