BLD 324 LEARNING OBJECTIVES EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS GRADED A++
Hematopoiesis
Production of blood cells, switches with age as to where the blood cells are made
Cytokine
Cellular products that influence the function and activity of other cells
Erythroblasts
an immature erythrocyte, containing a nucleus.
Erythropoiesis
red blood cell production in the bone marrow
Medullary
The medullary cavity (medulla, innermost part) is the central cavity of bone shafts where
red bone marrow and/or yellow bone marrow (adipose tissue) is stored; hence, the
medullary cavity is also known as the marrow cavity.
Myeloid
relating to bone marrow
Extramedullary hematopoiesis
hematopoiesis outside bone marrow (e.g., spleen)
Red marrow
Active marrow
The hematopoietic cords
,Yellow marrow
-Hematopoietically inactive
-Adipocytes
-Fatty marrow
Erythrocyte island
Surround macrophage, usually near sinus lining.
For each phase of hematopoiesis name the hemoglobin produced and the site of
cell production. Also, differentiate these for children and adults:
Mesoblastic phase
-19-20 days gestation
-Blood islands-form on yolk sac
-Yolk sac stem cells differentiate into primitive blood cells of all kinds
-Primitive erythroblasts:
1) remain nucleated and only have 1 stage of development
2)Synthesize embryonic hemoglobins: Portland, Gower I, and Gower II.
For each phase of hematopoiesis name the hemoglobin produced and the site of
cell production. Also, differentiate these for children and adults:
, Hepatic phase
-begins third month of gestation
-Embryonic liver becomes site of hematopoiesis through 7th month. The spleen, lymph
nodes, and thymus are also involved to a lesser degree).
-Erythropoiesis is established (all developmental forms are seen).
-Erythroblasts now mature
-Fetal hemoglobin (HbF)
For each phase of hematopoiesis name the hemoglobin produced and the site of
cell production. Also, differentiate these for children and adults:
Medullary (Myeloid) Phase
-Fifth month of gestation onward.
-Hematopoiesis becomes evident in the developing bone marrow, includes: WBCs,
RBCs, and megakaryocytes.
-Extramedullary hematopoiesis subsides toward birth
ANSWERS WITH COMPLETE SOLUTIONS GRADED A++
Hematopoiesis
Production of blood cells, switches with age as to where the blood cells are made
Cytokine
Cellular products that influence the function and activity of other cells
Erythroblasts
an immature erythrocyte, containing a nucleus.
Erythropoiesis
red blood cell production in the bone marrow
Medullary
The medullary cavity (medulla, innermost part) is the central cavity of bone shafts where
red bone marrow and/or yellow bone marrow (adipose tissue) is stored; hence, the
medullary cavity is also known as the marrow cavity.
Myeloid
relating to bone marrow
Extramedullary hematopoiesis
hematopoiesis outside bone marrow (e.g., spleen)
Red marrow
Active marrow
The hematopoietic cords
,Yellow marrow
-Hematopoietically inactive
-Adipocytes
-Fatty marrow
Erythrocyte island
Surround macrophage, usually near sinus lining.
For each phase of hematopoiesis name the hemoglobin produced and the site of
cell production. Also, differentiate these for children and adults:
Mesoblastic phase
-19-20 days gestation
-Blood islands-form on yolk sac
-Yolk sac stem cells differentiate into primitive blood cells of all kinds
-Primitive erythroblasts:
1) remain nucleated and only have 1 stage of development
2)Synthesize embryonic hemoglobins: Portland, Gower I, and Gower II.
For each phase of hematopoiesis name the hemoglobin produced and the site of
cell production. Also, differentiate these for children and adults:
, Hepatic phase
-begins third month of gestation
-Embryonic liver becomes site of hematopoiesis through 7th month. The spleen, lymph
nodes, and thymus are also involved to a lesser degree).
-Erythropoiesis is established (all developmental forms are seen).
-Erythroblasts now mature
-Fetal hemoglobin (HbF)
For each phase of hematopoiesis name the hemoglobin produced and the site of
cell production. Also, differentiate these for children and adults:
Medullary (Myeloid) Phase
-Fifth month of gestation onward.
-Hematopoiesis becomes evident in the developing bone marrow, includes: WBCs,
RBCs, and megakaryocytes.
-Extramedullary hematopoiesis subsides toward birth
