,
,CROWLEY’S
AN INTRODUCTION TO
HUMAN
DISEASE
Pathology and Pathophysiology Correlations
ELEVENTH EDITION
Emily G. Reisner, PhD
Faculty, Physician’s Assistant Program
Duke University
Durham, NC
Howard M. Reisner, PhD
Ptofessor of Pathology
University of North Carolina
Chapel Hill, NC
Associate Professor of Pathology
Campbell University School of Osteopathic Medicine
Lillington, NC
, World Headquarters
Jones & Bartlett Learning
5 Wall Street
Burlington, MA 01803
978-443-5000
www.jblearning.com
Jones & Bartlett Learning books and products are available through most bookstores and online booksellers. To contact Jones & Bartlett
Learning directly, call 800-832-0034, fax 978-443-8000, or visit our website, www.jblearning.com.
Substantial discounts on bulk quantities of Jones & Bartlett Learning publications are available to corporations, professional associations,
and other qualified organizations. For details and specific discount information, contact the special sales department at Jones & Bartlett
Learning via the above contact information or send an email to .
Copyright © 2022 by Jones & Bartlett Learning, LLC, an Ascend Learning Company
All rights reserved. No part of the material protected by this copyright may be reproduced or utilized in any form, electronic or mechanical,
including photocopying, recording, or by any information storage and retrieval system, without written permission from the copyright owner.
The content, statements, views, and opinions herein are the sole expression of the respective authors and not that of Jones & Bartlett Learning,
LLC. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not
constitute or imply its endorsement or recommendation by Jones & Bartlett Learning, LLC and such reference shall not be used for advertising
or product endorsement purposes. All trademarks displayed are the trademarks of the parties noted herein. Crowley’s An Introduction to
Human Disease: Pathology and Pathophysiology Correlations, Eleventh Edition is an independent publication and has not been authorized,
sponsored, or otherwise approved by the owners of the trademarks or service marks referenced in this product.
There may be images in this book that feature models; these models do not necessarily endorse, represent, or participate in the activities
represented in the images. Any screenshots in this product are for educational and instructive purposes only. Any individuals and scenarios
featured in the case studies throughout this product may be real or fictitious, but are used for instructional purposes only.
The authors, editor, and publisher have made every effort to provide accurate information. However, they are not responsible for errors,
omissions, or for any outcomes related to the use of the contents of this book and take no responsibility for the use of the products and procedures
described. Treatments and side effects described in this book may not be applicable to all people; likewise, some people may require a dose or
experience a side effect that is not described herein. Drugs and medical devices are discussed that may have limited availability controlled by the
Food and Drug Administration (FDA) for use only in a research study or clinical trial. Research, clinical practice, and government regulations
often change the accepted standard in this field. When consideration is being given to use of any drug in the clinical setting, the health care
provider or reader is responsible for determining FDA status of the drug, reading the package insert, and reviewing prescribing information for
the most up-to-date recommendations on dose, precautions, and contraindications, and determining the appropriate usage for the product. This
is especially important in the case of drugs that are new or seldom used.
18390-0
Production Credits
VP, Product Management: Amanda Martin VP, Manufacturing and Inventory Control: Therese Connell
Director of Product Management: Cathy L. Esperti Composition: Exela Technologies
Content Strategist: Ashley Malone Cover Design: Scott Moden
Content Coordinator: Elena Sorrentino Text Design: Scott Moden
Project Manager: Kristen Rogers Senior Media Development Editor: Troy Liston
Senior Project Specialist: Alex Schab Rights Specialist: Benjamin Roy
Senior Digital Project Specialist: Angela Dooley Cover Image (Title Page, Chapter Opener):
Director of Marketing: Andrea DeFronzo © Pan Xunbin/Shutterstock
Production Services Manager: Colleen Lamy Printing and Binding: LSC Communications
Library of Congress Cataloging-in-Publication Data
Names: Reisner, Emily G., author. | Reisner, Howard M., author.
Title: Crowley’s an introduction to human disease : pathology and
pathophysiology correlations / Emily G. Reisner, Howard M. Reisner.
Other titles: Introduction to human disease
Description: Eleventh edition. | Burlington, MA : Jones & Bartlett
Learning, [2021] | Includes bibliographical references and index.
Identifiers: LCCN 2020015927 | ISBN 9781284183832 (paperback)
Subjects: MESH: Disease | Pathology
Classification: LCC RC46 | NLM QZ 140 | DDC 616—dc23
LC record available at https://lccn.loc.gov/2020015927
6048
Printed in the United States of America
24 23 22 21 20 10 9 8 7 6 5 4 3 2 1
,CROWLEY’S
AN INTRODUCTION TO
HUMAN
DISEASE
Pathology and Pathophysiology Correlations
ELEVENTH EDITION
Emily G. Reisner, PhD
Faculty, Physician’s Assistant Program
Duke University
Durham, NC
Howard M. Reisner, PhD
Ptofessor of Pathology
University of North Carolina
Chapel Hill, NC
Associate Professor of Pathology
Campbell University School of Osteopathic Medicine
Lillington, NC
, World Headquarters
Jones & Bartlett Learning
5 Wall Street
Burlington, MA 01803
978-443-5000
www.jblearning.com
Jones & Bartlett Learning books and products are available through most bookstores and online booksellers. To contact Jones & Bartlett
Learning directly, call 800-832-0034, fax 978-443-8000, or visit our website, www.jblearning.com.
Substantial discounts on bulk quantities of Jones & Bartlett Learning publications are available to corporations, professional associations,
and other qualified organizations. For details and specific discount information, contact the special sales department at Jones & Bartlett
Learning via the above contact information or send an email to .
Copyright © 2022 by Jones & Bartlett Learning, LLC, an Ascend Learning Company
All rights reserved. No part of the material protected by this copyright may be reproduced or utilized in any form, electronic or mechanical,
including photocopying, recording, or by any information storage and retrieval system, without written permission from the copyright owner.
The content, statements, views, and opinions herein are the sole expression of the respective authors and not that of Jones & Bartlett Learning,
LLC. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not
constitute or imply its endorsement or recommendation by Jones & Bartlett Learning, LLC and such reference shall not be used for advertising
or product endorsement purposes. All trademarks displayed are the trademarks of the parties noted herein. Crowley’s An Introduction to
Human Disease: Pathology and Pathophysiology Correlations, Eleventh Edition is an independent publication and has not been authorized,
sponsored, or otherwise approved by the owners of the trademarks or service marks referenced in this product.
There may be images in this book that feature models; these models do not necessarily endorse, represent, or participate in the activities
represented in the images. Any screenshots in this product are for educational and instructive purposes only. Any individuals and scenarios
featured in the case studies throughout this product may be real or fictitious, but are used for instructional purposes only.
The authors, editor, and publisher have made every effort to provide accurate information. However, they are not responsible for errors,
omissions, or for any outcomes related to the use of the contents of this book and take no responsibility for the use of the products and procedures
described. Treatments and side effects described in this book may not be applicable to all people; likewise, some people may require a dose or
experience a side effect that is not described herein. Drugs and medical devices are discussed that may have limited availability controlled by the
Food and Drug Administration (FDA) for use only in a research study or clinical trial. Research, clinical practice, and government regulations
often change the accepted standard in this field. When consideration is being given to use of any drug in the clinical setting, the health care
provider or reader is responsible for determining FDA status of the drug, reading the package insert, and reviewing prescribing information for
the most up-to-date recommendations on dose, precautions, and contraindications, and determining the appropriate usage for the product. This
is especially important in the case of drugs that are new or seldom used.
18390-0
Production Credits
VP, Product Management: Amanda Martin VP, Manufacturing and Inventory Control: Therese Connell
Director of Product Management: Cathy L. Esperti Composition: Exela Technologies
Content Strategist: Ashley Malone Cover Design: Scott Moden
Content Coordinator: Elena Sorrentino Text Design: Scott Moden
Project Manager: Kristen Rogers Senior Media Development Editor: Troy Liston
Senior Project Specialist: Alex Schab Rights Specialist: Benjamin Roy
Senior Digital Project Specialist: Angela Dooley Cover Image (Title Page, Chapter Opener):
Director of Marketing: Andrea DeFronzo © Pan Xunbin/Shutterstock
Production Services Manager: Colleen Lamy Printing and Binding: LSC Communications
Library of Congress Cataloging-in-Publication Data
Names: Reisner, Emily G., author. | Reisner, Howard M., author.
Title: Crowley’s an introduction to human disease : pathology and
pathophysiology correlations / Emily G. Reisner, Howard M. Reisner.
Other titles: Introduction to human disease
Description: Eleventh edition. | Burlington, MA : Jones & Bartlett
Learning, [2021] | Includes bibliographical references and index.
Identifiers: LCCN 2020015927 | ISBN 9781284183832 (paperback)
Subjects: MESH: Disease | Pathology
Classification: LCC RC46 | NLM QZ 140 | DDC 616—dc23
LC record available at https://lccn.loc.gov/2020015927
6048
Printed in the United States of America
24 23 22 21 20 10 9 8 7 6 5 4 3 2 1