Biochemistry I- Rutgers Exam 1
Questions and Answers 100% Pass
Which will show the greater degree of dissociation: formic acid (pKa = 3.75) or acetic
acid (pKa = 4.76) if dissolved in water at 0.1 M concentrations?
A. Formic acid C. Within the accuracy of measurement they will be equally dissociated.
B. Acetic acid D. Cannot tell from data given. - ✔✔A. Formic acid
Which will show the greater degree of dissociation: formic acid (pKa = 3.75) or acetic
acid (pKa = 4.76) if dissolved at 0.1 M concentrations in solutions whose pH is 11.0?
A. Formic acid C. Within the accuracy of measurement they will be equally dissociated.
B. Acetic acid D. Cannot tell from data given. - ✔✔C. Within the accuracy of
measurement they will be equally dissociated.
Which of the following experimental observations disproved the vitalist claim that the
substances of which living matter is composed are qualitatively different from those
which compose the non-living world?
A. the demonstration by the Buchner brothers that broken and therefore dead yeast
cells could convert sugar into ethanol B. the crystallization by Sumner of the enzyme
Katelyn Whitman, All Rights Reserved © 2025 1
,urease C. Pasteur's proof that living organisms arise only from other living organisms
rather than by spontaneous generation caused by the "vital force" D. Wöhler's synthesis
of urea from ammonium cyanate E. none of the above - ✔✔D. Wöhler's synthesis of
urea from ammonium cyanate
At pH 6.5 ribonuclease-A has a net charge of +4. At pH 2 the protein has a net charge of
+19. If the protein is dissolved in 0.1 M KCl at both pHs, and if the solution contains no
other solutes, in which case will the protein molecules have a larger number of chloride
ions in their immediate vicinity?
A. pH 2 C. a pH midway between 2 and 6.5 B. pH 6.5 D. It will have the same number
of chlorides at the two pHs. E. cannot tell from data given. - ✔✔A. PH 2
The free energy of a reaction which is not at equilibrium, such as is the case in nearly all
cellular reactions, involves two terms: the standard free energy at equilibrium and a
term expressing the deviation of the actual
conditions from equilibrium. In the Henderson-Hasselbalch equation governing buffers,
the equivalent of the standard free energy term occurs at the pH at which
Katelyn Whitman, All Rights Reserved © 2025 2
, A. the weak acid is fully dissociated. D. half the weak acid is dissociated. B. the weak
acid is fully in the undissociated form. E. none of the above. C. the pH = the pI. - ✔✔D.
the weak acid is fully in the undissociated form
Which of the following is best described as an entropy driven reaction?
A. H = -82 kJ/mol, -TS = -136 kJ/mol D. none of the above is entropy driven B. H = -
1367 kJ/mol, -TS = +41 kJ/mol E. all the above are entropy driven. C. H = +110 kJ/mol,
-TS = -140 kJ/mol - ✔✔C. delta H= +110 kJ/mol
Rank the following vitalist statements in order of decreasing breadth of their claims
about the living world.
1. Living matter may be composed of the same materials as non-living matter, but
organisms arise from non-living matter by spontaneous generation by intervention of
the "vital force." 2. The substances composing living mater are qualitatively different
from those of the non-living world. 3. The structure of enzymes is too complex to be
described in chemical terms, and the nature of biological catalysis is not
comprehensible. 4. We may be able to make some of the substances of living matter, but
the reactions which constitute life occur only in living cells.
Katelyn Whitman, All Rights Reserved © 2025 3
Questions and Answers 100% Pass
Which will show the greater degree of dissociation: formic acid (pKa = 3.75) or acetic
acid (pKa = 4.76) if dissolved in water at 0.1 M concentrations?
A. Formic acid C. Within the accuracy of measurement they will be equally dissociated.
B. Acetic acid D. Cannot tell from data given. - ✔✔A. Formic acid
Which will show the greater degree of dissociation: formic acid (pKa = 3.75) or acetic
acid (pKa = 4.76) if dissolved at 0.1 M concentrations in solutions whose pH is 11.0?
A. Formic acid C. Within the accuracy of measurement they will be equally dissociated.
B. Acetic acid D. Cannot tell from data given. - ✔✔C. Within the accuracy of
measurement they will be equally dissociated.
Which of the following experimental observations disproved the vitalist claim that the
substances of which living matter is composed are qualitatively different from those
which compose the non-living world?
A. the demonstration by the Buchner brothers that broken and therefore dead yeast
cells could convert sugar into ethanol B. the crystallization by Sumner of the enzyme
Katelyn Whitman, All Rights Reserved © 2025 1
,urease C. Pasteur's proof that living organisms arise only from other living organisms
rather than by spontaneous generation caused by the "vital force" D. Wöhler's synthesis
of urea from ammonium cyanate E. none of the above - ✔✔D. Wöhler's synthesis of
urea from ammonium cyanate
At pH 6.5 ribonuclease-A has a net charge of +4. At pH 2 the protein has a net charge of
+19. If the protein is dissolved in 0.1 M KCl at both pHs, and if the solution contains no
other solutes, in which case will the protein molecules have a larger number of chloride
ions in their immediate vicinity?
A. pH 2 C. a pH midway between 2 and 6.5 B. pH 6.5 D. It will have the same number
of chlorides at the two pHs. E. cannot tell from data given. - ✔✔A. PH 2
The free energy of a reaction which is not at equilibrium, such as is the case in nearly all
cellular reactions, involves two terms: the standard free energy at equilibrium and a
term expressing the deviation of the actual
conditions from equilibrium. In the Henderson-Hasselbalch equation governing buffers,
the equivalent of the standard free energy term occurs at the pH at which
Katelyn Whitman, All Rights Reserved © 2025 2
, A. the weak acid is fully dissociated. D. half the weak acid is dissociated. B. the weak
acid is fully in the undissociated form. E. none of the above. C. the pH = the pI. - ✔✔D.
the weak acid is fully in the undissociated form
Which of the following is best described as an entropy driven reaction?
A. H = -82 kJ/mol, -TS = -136 kJ/mol D. none of the above is entropy driven B. H = -
1367 kJ/mol, -TS = +41 kJ/mol E. all the above are entropy driven. C. H = +110 kJ/mol,
-TS = -140 kJ/mol - ✔✔C. delta H= +110 kJ/mol
Rank the following vitalist statements in order of decreasing breadth of their claims
about the living world.
1. Living matter may be composed of the same materials as non-living matter, but
organisms arise from non-living matter by spontaneous generation by intervention of
the "vital force." 2. The substances composing living mater are qualitatively different
from those of the non-living world. 3. The structure of enzymes is too complex to be
described in chemical terms, and the nature of biological catalysis is not
comprehensible. 4. We may be able to make some of the substances of living matter, but
the reactions which constitute life occur only in living cells.
Katelyn Whitman, All Rights Reserved © 2025 3
