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Role of Vascular System
- Give to different organs
-Take from organs
-Circulate
What does the vascular system give to different organs
Oxygen, Nutrients
What does the vascular system take from different organs
Carbon Dioxide, Metabolic Waste
What does the vascular system circulate
-Hormones
-Antibodies
-Immune Cells
Ohms law for fluids
Blood Flow (Q) = ΔP/R
P = pressure gradient
R = vessel resistance
PRESSURE GRADIENT MUST BE POSITIVE IN ORDER FOR BLOOD TO FLOW
Poiseuille's Equation
R = 8Lvη / πr^4
L = Length of vessel
r = radius of blood vessel
η = Coefficient of Viscosity
Hematocrit
Percent of red blood cells
Plasma is made of
water and proteins
The greater the hematocrit
the greater the viscosity
(ANOMALOUS VISCOSITY)
Why doesn't blood flow according to ohms law at low pressure?
The red blood cells form formed elements, which increases the apparent viscosity.
-Increase in viscosity = increase in resistance
- Increase in resistance causes flow to not increase in proportion to increase in gradient
pressure
Formed Elements
, -what RBCs form into at low pressure
- Does not increase in proportion to increase in gradient pressure (Anomalous Viscosity)
Laminar Flow
-Velocity of blood is highest along the axis and lowest among the law
Fahreous - Lindquist Effect
-If vessel is smaller than 100μM, axial streaming causes hematocrit to decrease.
- hematocrit drop = viscosity drop
- viscosity drop = resistance drop
- resistance drop helps blood flow through small diameter vessels
axial streaming
- RBCs move along the axis (faster)
- Plasma move along the walls of the vessel (slower)
- Hematocrit drops
flow rate
the volume of blood that passes a given point in the system per unit time
velocity of flow
the distance a fixed volume of blood travels in a given period of time
First part of the vascular system
Aorta
10 components of vascular system
Left ventricle pumps blood into
1. Aorta
2. Ascending Arteries or Abdominal aorta
3. Arteries
4. Arterioles
5. Small Arterioles
6. Capillaries
7. Venules
8. Veins
9. Great veins
10. Superior or Inferior Vena Cava
Which releases into the Atrium
Aorta
- Smallest cross sectional area in body (highest velocity)
- first part of the vascular system
- most elastic component of a blood vessel
-Pressure reservoir
Abdominal aorta
Feed the lower trunk of the body
Capillaries
- Not apart of arterial network or venous network
-Where the exchange of o2 and co2 happens
- Organs give CO2