QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS
GRADED A++
pharmacodymanics:
the study of the drug and how it interacts with the molecular taget
- what the drug does to the body, the mechinism of action
drug action usually works in one of 4 ways:
replace or act as a substitute for missing substances
stimulate if increase a cellualr activity
depress or slow cellular activity
interfere with function of foregin cells
what do drugs do:
drugs donot confer any new function to cells, tissues or organs
they modify existing functions
this could be done by:
- bind to protein target
, - combine with other molecules
- alter membrane activity
receptors
- usually for a drug to produce an effect there has to be some receptor with whcih it can
react
- 4 primary drug tagets
- receptors generally have specific physiological roles and drugs are either accentuating
or blocking the action of the drug
4 primay drug targets(receptors):
enzymes
carrier molecules
ion channels
specific receptors
places in body drugs my be:
free inn plasma
bound to plasma proteins
bound to a receptor
bound to a tissue
For a Drug to be Effective it must be