ANSWERS 2025 UPDATE.
Neuromusclar condition can be find in what level of evidence the best? - ANS level 3, case
report
ALS has degeneration of - ANS 1. anterior horn cell
2. motor cranial n. nuceli
3. gliosis of cortiospinal and corticobulubar tract
What is the nick name of amyotrophic lateral sclerosis - ANS Lou Gehrig's disease
T/F more than 1/2 of all pt live > 2 years in ALS - ANS F. > 3 years
How many % of people live more than 5 years in ALS - ANS 20%
how many percent will survive more than 10 years in ALS - ANS 10%
mean age of ALS - ANS 57 (range 50-70)
What is the strong "definite" ALS? - ANS must be upper and motor neuron deficits
neither 3 spinal regions, or 2 spinal region + 1 bulbur
What is the progression of ALS, put them in order T/F
1. bulbar involvement in early stage
2. lower extremities before upper extremities
3. proximal before distal - ANS 1. F
2. T
3. F
What r the two medication for ALS? What is the function? - ANS 1. Riluzole. Inhibit pre-
synaptic release of glutamate, 1st FDA approved, prolong survival by months
2. Minocycline
What are the three phases of the ALS? - ANS independent, particularly independent, dependent
What are the exercise consideration you would do for ALS?
how many rep? resistance work? - ANS 1. low resistance, high rep
2. when 3+ starts to do resistance work but not eccentric
3. pressure release