Test Bank for HUETHER and MCCANCES Understanding Path
g g g g g g g
ophysiology, Canadian Edition 2nd Edition by Kelly Power-
g g g g g g g
Kean,Stephanie Zettel, Mohamed TOUFIC El-
g g g g
Hussein, Sue E.HUETHER, Kathryn L. MCCANCE | 978032377
g g g g g g g
8848 | 2024 Chapter 1-42
g g g g
Chapter 01: Cellular Biology Huether & McCance: Understanding Pathophysiology, 6th
g g g g g g g g g
Edition
g
MULTIPLEgCHOICE
1. Agstudentgisgobservinggagcellgundergthegmicroscope.gItgisgobservedgtoghavegsupercoiledgDNAg
withghistones.gWhichgofgthegfollowinggwouldgalsogbegobservedgbygthegstudent?ga.gAgsinglegcir
culargchromosome
b. Agnucleus
c. Free-floatinggnucleargmaterial
d. Nogorganelles
ANS:gB
Thegcellgdescribedgisgageukaryoticgcell,gsogitghasghistonesgandgagsupercoiledgDNAgwithingitsgnucle
us;gthus,gthegnucleusgshouldgbegobserved.gAgsinglegcirculargchromosomegcalledgagprokaryotegco
ntainsgfree-floatinggnucleargmaterialgbutghasgnogorganelles.
REF:gp.g2
2. Agnursegisginstructinggthegstaffgaboutgcellulargfunctions.gWhichgcellulargfunctiongisgthegnursegdesc
ribinggwhengangisolatedgcellgabsorbsgoxygengandgusesgitgtogtransformgnutrientsgtogenergy?ga.
Metabolicgabsorption
b. Communication
c. Secretion
d. Respiration
ANS:gD
Thegcell’sgabilitygtogabsorbgoxygengisgreferredgtogasgrespirationgwhilegitsgcommunicationgabilitygin
volvesgmaintenancegofgagsteadygdynamicgstate,gmetabolicgabsorptiongprovidesgnutrition,gandgsecre
tiongallowsgforgthegsynthesizinggofgnewgsubstances.
REF:gp.g2
3. AgeukaryoticgcellgisgundergoinggDNAgreplication.gIngwhichgregiongofgthegcellgwouldgmostgofgthegg
eneticginformationgbegcontained?
a. Mitochondria
,b. Ribosome
c. Nucleolus
d. NucleusgCytoplasm
, ANS:gC
Thegregiongofgthegcellgthatgcontainsggeneticgmaterial,gincludinggaglargegamountgofgribonucleicgaci
d,gmostgofgthegDNA,gandgDNA-
bindinggproteins,gisgthegnucleolus,gwhichgisglocatedgwithingthegcell’sgnucleus.gMitochondriagisgas
sociatedgwithgcellulargrespiration,gwhilegribosomesgareginvolvedgwithgproteingmanufacturing.gC
ytoplasmgisgagfluidgfillinggthatgisgagcomponentgofgthegcell.
REF:gp.g2
4. Whichgofgthegfollowinggcangremovegproteinsgattachedgtogthegcell’sgbilayergbygdissolvinggtheglayergit
self?
a. Peripheralgmembranegproteins
b. Integralgmembranegproteins
c. Glycoproteins
d. Cellgadhesiongmolecules
ANS:gB
Proteinsgdirectlygattachedgtogthegmembranegbilayergcangbegremovedgbygthegactiongofgintegralgme
mbranegproteinsgthatgdissolvegthegbilayer.gPeripheralgmembranegproteinsgresidegatgthegsurfacegw
hilegcellgadhesiongmoleculesgaregongthegoutsidegofgthegmembrane.gGlycoproteingmarksgcellsgandg
doesgnotgfloat.
REF:gp.g7
5. Whichgofgthegfollowinggcangbindgtogplasmagmembranegreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicglipids
d. Ligands
ANS:gD
Ligandsgaregthegonlygspecificgmoleculesgthatgcangbindgwithgreceptorsgongthegcellgmembrane.
REF:gp.g9
6. Agnursegisgreviewinggagreportgfromgagpatientgwithgmetastaticgcancer.gWhatgalternationgingthege
xtracellulargmatrixgwouldgsupportgthegdiagnosisgofgmetastaticgcancer?a.
Decreasedgfibronectin
b. Increasedgcollagen
c. Decreasedgelastin
d. Increasedgglycoproteins
, ANS:gA
Onlygagreducedgamountgofgfibronectingisgfoundgingsomegtypesgofgcancerousgcells,gallowinggthemg
togtravelgorgmetastasize.
REF:gp.g10
7. Whichgformgofgcellgcommunicationgisgusedgtogrelategtogothergcellsgingdirectgphysicalgcontact?ga.
Cellgjunction
b. Gapgjunction
c. Desmosome
d. Tightgjunction
ANS:gA
Cellgjunctionsgholdgcellsgtogethergandgpermitgmoleculesgtogpassgfromgcellgtogcell.
Gapgjunctionsgallowgforgcellulargcommunicationgbetweengcells.gNeithergdesmosomesgnorgtightgj
unctionsgaregassociatedgwithgcellulargcommunication.
REF:gp.g11
8. Pancreaticgbetagcellsgsecreteginsulin,gwhichginhibitsgsecretiongofgglucagongfromgneighboringgalphagc
ells.gThisgactiongisgangexamplegofgwhichgofgthegfollowinggsignalinggtypes?ga.gParacrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:gA
Paracrinegsignalingginvolvesgthegreleasegofglocalgchemicalgmediatorsgthatgaregquicklygtakengup,gd
estroyed,gorgimmobilized,gasgingthegcasegofginsulingandgtheginhibitiongofgthegsecretiongofgglucago
n.gNonegofgthegothergoptionsginvolvegsignalinggthatgisgassociatedgwithgaglocalgchemicalgmediatorg
likeginsulin.
REF:gp.g12
9. Ingcellulargmetabolism,geachgenzymeghasgaghighgaffinitygforga:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:gB
g g g g g g g
ophysiology, Canadian Edition 2nd Edition by Kelly Power-
g g g g g g g
Kean,Stephanie Zettel, Mohamed TOUFIC El-
g g g g
Hussein, Sue E.HUETHER, Kathryn L. MCCANCE | 978032377
g g g g g g g
8848 | 2024 Chapter 1-42
g g g g
Chapter 01: Cellular Biology Huether & McCance: Understanding Pathophysiology, 6th
g g g g g g g g g
Edition
g
MULTIPLEgCHOICE
1. Agstudentgisgobservinggagcellgundergthegmicroscope.gItgisgobservedgtoghavegsupercoiledgDNAg
withghistones.gWhichgofgthegfollowinggwouldgalsogbegobservedgbygthegstudent?ga.gAgsinglegcir
culargchromosome
b. Agnucleus
c. Free-floatinggnucleargmaterial
d. Nogorganelles
ANS:gB
Thegcellgdescribedgisgageukaryoticgcell,gsogitghasghistonesgandgagsupercoiledgDNAgwithingitsgnucle
us;gthus,gthegnucleusgshouldgbegobserved.gAgsinglegcirculargchromosomegcalledgagprokaryotegco
ntainsgfree-floatinggnucleargmaterialgbutghasgnogorganelles.
REF:gp.g2
2. Agnursegisginstructinggthegstaffgaboutgcellulargfunctions.gWhichgcellulargfunctiongisgthegnursegdesc
ribinggwhengangisolatedgcellgabsorbsgoxygengandgusesgitgtogtransformgnutrientsgtogenergy?ga.
Metabolicgabsorption
b. Communication
c. Secretion
d. Respiration
ANS:gD
Thegcell’sgabilitygtogabsorbgoxygengisgreferredgtogasgrespirationgwhilegitsgcommunicationgabilitygin
volvesgmaintenancegofgagsteadygdynamicgstate,gmetabolicgabsorptiongprovidesgnutrition,gandgsecre
tiongallowsgforgthegsynthesizinggofgnewgsubstances.
REF:gp.g2
3. AgeukaryoticgcellgisgundergoinggDNAgreplication.gIngwhichgregiongofgthegcellgwouldgmostgofgthegg
eneticginformationgbegcontained?
a. Mitochondria
,b. Ribosome
c. Nucleolus
d. NucleusgCytoplasm
, ANS:gC
Thegregiongofgthegcellgthatgcontainsggeneticgmaterial,gincludinggaglargegamountgofgribonucleicgaci
d,gmostgofgthegDNA,gandgDNA-
bindinggproteins,gisgthegnucleolus,gwhichgisglocatedgwithingthegcell’sgnucleus.gMitochondriagisgas
sociatedgwithgcellulargrespiration,gwhilegribosomesgareginvolvedgwithgproteingmanufacturing.gC
ytoplasmgisgagfluidgfillinggthatgisgagcomponentgofgthegcell.
REF:gp.g2
4. Whichgofgthegfollowinggcangremovegproteinsgattachedgtogthegcell’sgbilayergbygdissolvinggtheglayergit
self?
a. Peripheralgmembranegproteins
b. Integralgmembranegproteins
c. Glycoproteins
d. Cellgadhesiongmolecules
ANS:gB
Proteinsgdirectlygattachedgtogthegmembranegbilayergcangbegremovedgbygthegactiongofgintegralgme
mbranegproteinsgthatgdissolvegthegbilayer.gPeripheralgmembranegproteinsgresidegatgthegsurfacegw
hilegcellgadhesiongmoleculesgaregongthegoutsidegofgthegmembrane.gGlycoproteingmarksgcellsgandg
doesgnotgfloat.
REF:gp.g7
5. Whichgofgthegfollowinggcangbindgtogplasmagmembranegreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicglipids
d. Ligands
ANS:gD
Ligandsgaregthegonlygspecificgmoleculesgthatgcangbindgwithgreceptorsgongthegcellgmembrane.
REF:gp.g9
6. Agnursegisgreviewinggagreportgfromgagpatientgwithgmetastaticgcancer.gWhatgalternationgingthege
xtracellulargmatrixgwouldgsupportgthegdiagnosisgofgmetastaticgcancer?a.
Decreasedgfibronectin
b. Increasedgcollagen
c. Decreasedgelastin
d. Increasedgglycoproteins
, ANS:gA
Onlygagreducedgamountgofgfibronectingisgfoundgingsomegtypesgofgcancerousgcells,gallowinggthemg
togtravelgorgmetastasize.
REF:gp.g10
7. Whichgformgofgcellgcommunicationgisgusedgtogrelategtogothergcellsgingdirectgphysicalgcontact?ga.
Cellgjunction
b. Gapgjunction
c. Desmosome
d. Tightgjunction
ANS:gA
Cellgjunctionsgholdgcellsgtogethergandgpermitgmoleculesgtogpassgfromgcellgtogcell.
Gapgjunctionsgallowgforgcellulargcommunicationgbetweengcells.gNeithergdesmosomesgnorgtightgj
unctionsgaregassociatedgwithgcellulargcommunication.
REF:gp.g11
8. Pancreaticgbetagcellsgsecreteginsulin,gwhichginhibitsgsecretiongofgglucagongfromgneighboringgalphagc
ells.gThisgactiongisgangexamplegofgwhichgofgthegfollowinggsignalinggtypes?ga.gParacrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:gA
Paracrinegsignalingginvolvesgthegreleasegofglocalgchemicalgmediatorsgthatgaregquicklygtakengup,gd
estroyed,gorgimmobilized,gasgingthegcasegofginsulingandgtheginhibitiongofgthegsecretiongofgglucago
n.gNonegofgthegothergoptionsginvolvegsignalinggthatgisgassociatedgwithgaglocalgchemicalgmediatorg
likeginsulin.
REF:gp.g12
9. Ingcellulargmetabolism,geachgenzymeghasgaghighgaffinitygforga:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:gB