NR601/ NR 601 Midterm Exams (Latest 2025 Updates) Questions and
Verified Answers| 100% Correct |Grade A +
Biochemical individuality is best described as: - ANSWER-Each individual's
variation is often much smaller than that of a larger group
All the following statements about drug absorption are false except: - ANSWER-
Underlying chronic dz has little impact on drug absorption
The cytochrome p system involves enzymes that are generally: - ANSWER-
Inhibited or induced by drugs
A statement not shown to be true about pharmacodynamic changes with aging is:
- ANSWER-Decreased sensitivity to oral anticoagulants
The major impact of the physiological changes that occur w/aging is: - ANSWER-
Reduced physiological reserve
Reduced homeostatic mechanisms
Impaired immunolgoical response
The strongest evidence regarding normal physiological aging is available through:
- ANSWER-Longitudinal studies
,Pharmacokinetic changes w/aging is reflective of: - ANSWER-What the body does
to the drug
All of the following statements are true about drug distribution in the elderly
except: - ANSWER-Drugs distributed in water have lower concentration
Men have faster and more efficient biotransformation of drugs and this is thought
to be due to: - ANSWER-Testosterone
Atypical presentation of dz in elderly is reflected by all the following except: -
ANSWER-MI w/CP and diaphoresis
Polypharmacy is best described as taking: - ANSWER-Even a single med if there is
not a clear indication for its use
What are the 3 primary physiological changes of aging? - ANSWER-1. Reduced
physiological reserve of most body systems, esp. cardiac, resp, renal.
2. Reduced homeostatic mechanisms that fail to adjust regulatory systems (i.e.
temp control, fluid/lyte balance, etc.).
,3. Impaired immunological function (infection risk is greater, autoimmune dz's
more prevalent)
What is the preferred amount of exercise for elderly? - ANSWER-30min/day 5
days/wk of moderate exercise.
If trying to lose wt: 60min/day.
What are PFTs? - ANSWER-Group of tests that provide quantifiable measurement
of lung function, used to dx resp abnormalities or assess progression/resolution
of lung dz.
What is FEV1? - ANSWER-Forced Expiratory Volume in 1 second (80-120%)
What is FVC? - ANSWER-Forced Vital Capacity (80-120%)
What is normal FEV1/FVC ratio? - ANSWER-<0.7 (70%)
What is GOLD 1 criteria? - ANSWER-Mild
FEV1 >/= 80% predicted
What is GOLD 2 criteria? - ANSWER-Moderate
, FEV1 50-79% predicted
What is GOLD 3 criteria? - ANSWER-Severe
FEV1 30-49% predicted
What is GOLD 4 criteria? - ANSWER-Very severe
FEV1 <30% predicted
What are the signal symptoms of COPD? - ANSWER-Dyspnea
Chronic cough w/sputum
Decreased activity tolerance
Wheezing
What are characteristics of COPD? - ANSWER-Common, preventable, treatable.
Characterized by persistent airflow limitation.
Usually progressive, associated with enhanced chronic inflammatory response in
airways and lungs to noxious particles/gases
Verified Answers| 100% Correct |Grade A +
Biochemical individuality is best described as: - ANSWER-Each individual's
variation is often much smaller than that of a larger group
All the following statements about drug absorption are false except: - ANSWER-
Underlying chronic dz has little impact on drug absorption
The cytochrome p system involves enzymes that are generally: - ANSWER-
Inhibited or induced by drugs
A statement not shown to be true about pharmacodynamic changes with aging is:
- ANSWER-Decreased sensitivity to oral anticoagulants
The major impact of the physiological changes that occur w/aging is: - ANSWER-
Reduced physiological reserve
Reduced homeostatic mechanisms
Impaired immunolgoical response
The strongest evidence regarding normal physiological aging is available through:
- ANSWER-Longitudinal studies
,Pharmacokinetic changes w/aging is reflective of: - ANSWER-What the body does
to the drug
All of the following statements are true about drug distribution in the elderly
except: - ANSWER-Drugs distributed in water have lower concentration
Men have faster and more efficient biotransformation of drugs and this is thought
to be due to: - ANSWER-Testosterone
Atypical presentation of dz in elderly is reflected by all the following except: -
ANSWER-MI w/CP and diaphoresis
Polypharmacy is best described as taking: - ANSWER-Even a single med if there is
not a clear indication for its use
What are the 3 primary physiological changes of aging? - ANSWER-1. Reduced
physiological reserve of most body systems, esp. cardiac, resp, renal.
2. Reduced homeostatic mechanisms that fail to adjust regulatory systems (i.e.
temp control, fluid/lyte balance, etc.).
,3. Impaired immunological function (infection risk is greater, autoimmune dz's
more prevalent)
What is the preferred amount of exercise for elderly? - ANSWER-30min/day 5
days/wk of moderate exercise.
If trying to lose wt: 60min/day.
What are PFTs? - ANSWER-Group of tests that provide quantifiable measurement
of lung function, used to dx resp abnormalities or assess progression/resolution
of lung dz.
What is FEV1? - ANSWER-Forced Expiratory Volume in 1 second (80-120%)
What is FVC? - ANSWER-Forced Vital Capacity (80-120%)
What is normal FEV1/FVC ratio? - ANSWER-<0.7 (70%)
What is GOLD 1 criteria? - ANSWER-Mild
FEV1 >/= 80% predicted
What is GOLD 2 criteria? - ANSWER-Moderate
, FEV1 50-79% predicted
What is GOLD 3 criteria? - ANSWER-Severe
FEV1 30-49% predicted
What is GOLD 4 criteria? - ANSWER-Very severe
FEV1 <30% predicted
What are the signal symptoms of COPD? - ANSWER-Dyspnea
Chronic cough w/sputum
Decreased activity tolerance
Wheezing
What are characteristics of COPD? - ANSWER-Common, preventable, treatable.
Characterized by persistent airflow limitation.
Usually progressive, associated with enhanced chronic inflammatory response in
airways and lungs to noxious particles/gases
