FNP2 Exam 2 blueprint GNRS 5670 Latest
Update 2025-2026 Actual Exam 140 Questions
with 100% Verified Correct Answers Guaranteed
A+ Verified by Professor
○ Enterovirus - poliomyelitis (fecal oral transmission) - CORRECT ANSWER:
○ Enteroviruses - non-polio - CORRECT ANSWER: ■ Ø10-15 serotypes account for
most diseases
■ ØMost common cause of aseptic meningitis
■ ØHand-foot-mouth, herpangina, acute hemorrhagic conjunctivitis, other
■ ØPrimary invasion through GI tract
■ ØTransmitted via respiratory route
■ ØTransplacental transmission can occur
■ ØInfants have highest prevalence rate
○ Enteroviruses - non-polio: clinical findings - CORRECT ANSWER: ■ ØHistory - mild
URI; nonspecific febrile illness >3 days; onset within 2 weeks after delivery
■ ØPhysical examination
● •Skin - macular, macular-papular, urticarial, vesicular, petechial
● •Herpangina - sudden onset of high fever; vesicular lesions on oropharynx, palate
● •Acute lymphonodular pharyngitis
● •Hand-foot-mouth disease - vesicles
● •Aseptic meningitis - fever, stiff neck, headache
○ Fever without focus - CORRECT ANSWER: ■ ØBirth-24 months at greatest risk
■ ØAcute febrile illness without obvious etiology
,■ ØTable 24-11 - most common pathogens
■ ØHistory and physical examination
○ Hep A - CORRECT ANSWER: ■ Good hand hygiene, esp after diaper changes
■ Fecal/oral transmission
■ Ig or HAV vaccine within 2 weeks of exposure
■ Good personal hygiene/safe drinking water (well water)
■ Routine HAV vaccine
■ ØCauses primary infection in liver
■ ØPerson-to-person; fecal-oral transmission
■ Ø<10% of young children develop jaundice; only 30% are symptomatic - allows for
rapid spread
■ ØClinical findings
● •Preicteric phase - acute febrile illness; malaise, nausea, anorexia, vomiting, digestive
complaints; may have RUQ pain
● •Icteric phase - jaundice, dark urine, clay-colored stools; feel sick; poor weight gain in
infants
■ ØFulminant disease rare; complete recovery in 1-2 months; occasional relapses up to
6 months
■ ØDiagnostic studies - serologic testing
■ ØDifferential diagnosis
● •Infancy - physiologic jaundice, hemolytic disease, galactosemia, hypothyroidism,
biliary disorders, hypervitaminosis A
● •Older infants, children, adolescents - hemolytic-uremic syndrome, Reye syndrome,
others
■ ØManagement, complications, prevention
● •Supportive care
● •Good hand hygiene, especially with diaper changes
● •Immunoglobulin or HAV vaccine within 2 weeks of exposure
,● •Good personal hygiene; safe drinking water
● •Routine HAV vaccine
○ Hep B: - CORRECT ANSWER: Perinatal transmission can occur
○ Herpes family of viruses - herpes simplex virus - CORRECT ANSWER: ■ Include HSV
1&2, Mononucleosis (EBV), Roseola infantum, varicella
■ ØWidely disseminated in humans
● •HSV-1 - orolabial lesions
● •HSV-2 - genital lesions
■ ØBoth types associated with oral/genital infections
■ ØBoth types devastating to newborns
■ ØType 1 most common in children as gingivostomatitis
■ ØType 2 usually result of sexual activity
■ HSV1 (can give you a genital outbreak but does not like to live there)
■ Should child with HSV1 fever blister be kept out of school?
● No
● Daycare drooling toddlers left out of daycare
● Wrestlers should not compete until lesions cleared
● Ask all pregnant women about HSV
■ Which is not true of HSV2: NOT most common as gingivostomatitis in children. It is:
● Cause of genital lesions
● Usually result of sexual activity
● Devastating to newborns
○ Herpes family of viruses - herpes simplex virus (Cont.) - CORRECT ANSWER: ■
ØNeonatal HSV-2 from mother during delivery
● •Conjunctivae, nose/mouth, broken skin
, ● •Can occur with C-section, asymptomatic shedding
■ ØPostnatal transmission, inoculation from fathers, lateral transmission from other
infants may occur
■ ØPeriod of communicability 2 days to 2 weeks
■ ØSome congenital infections occur >6 weeks
■ ØCan transmit from primary/recurrent infection
■ ØClinical findings - determined by port of entry, age, health, immune competence
■ ØNeonatal infection - always symptomatic
● •Disseminated - multiple organ failure; encephalitis - day 10-12 of life
● •CNS - focal/generalized seizures, lethargy, irritability, poor feeding, herpetic lesions -
day 16-19 of life
● •Skin, eye, mouth - limited to these sites - day 10-12 of life
■ ØTraumatic herpetic infection
● •Localized to area of abrasion, teething, laceration; inoculated by parent who kisses
site
● •Fever, constitutional symptoms, regional lymphadenopathy
■ ØAcute herpetic meningoencephalitis
■ ØRecurrent infection - virus is dormant; recurrent infections are common
■ ØDiagnostic studies
● •Intrapartum cultures mother/child; within 12-24 hours after delivery
■ ØDifferential diagnosis
● •Coxsackievirus if viral stomatitis (hand foot mouth)
● •Always suspect HSV with neonatal respiratory distress/sepsis
■ ØManagement
● •Parenteral acyclovir with life-threatening/neonatal infection
● •Oral acyclovir for 6 months after parenteral treatment
■ ØComplications
● •Most cases mild; may have secondary bacterial infection
Update 2025-2026 Actual Exam 140 Questions
with 100% Verified Correct Answers Guaranteed
A+ Verified by Professor
○ Enterovirus - poliomyelitis (fecal oral transmission) - CORRECT ANSWER:
○ Enteroviruses - non-polio - CORRECT ANSWER: ■ Ø10-15 serotypes account for
most diseases
■ ØMost common cause of aseptic meningitis
■ ØHand-foot-mouth, herpangina, acute hemorrhagic conjunctivitis, other
■ ØPrimary invasion through GI tract
■ ØTransmitted via respiratory route
■ ØTransplacental transmission can occur
■ ØInfants have highest prevalence rate
○ Enteroviruses - non-polio: clinical findings - CORRECT ANSWER: ■ ØHistory - mild
URI; nonspecific febrile illness >3 days; onset within 2 weeks after delivery
■ ØPhysical examination
● •Skin - macular, macular-papular, urticarial, vesicular, petechial
● •Herpangina - sudden onset of high fever; vesicular lesions on oropharynx, palate
● •Acute lymphonodular pharyngitis
● •Hand-foot-mouth disease - vesicles
● •Aseptic meningitis - fever, stiff neck, headache
○ Fever without focus - CORRECT ANSWER: ■ ØBirth-24 months at greatest risk
■ ØAcute febrile illness without obvious etiology
,■ ØTable 24-11 - most common pathogens
■ ØHistory and physical examination
○ Hep A - CORRECT ANSWER: ■ Good hand hygiene, esp after diaper changes
■ Fecal/oral transmission
■ Ig or HAV vaccine within 2 weeks of exposure
■ Good personal hygiene/safe drinking water (well water)
■ Routine HAV vaccine
■ ØCauses primary infection in liver
■ ØPerson-to-person; fecal-oral transmission
■ Ø<10% of young children develop jaundice; only 30% are symptomatic - allows for
rapid spread
■ ØClinical findings
● •Preicteric phase - acute febrile illness; malaise, nausea, anorexia, vomiting, digestive
complaints; may have RUQ pain
● •Icteric phase - jaundice, dark urine, clay-colored stools; feel sick; poor weight gain in
infants
■ ØFulminant disease rare; complete recovery in 1-2 months; occasional relapses up to
6 months
■ ØDiagnostic studies - serologic testing
■ ØDifferential diagnosis
● •Infancy - physiologic jaundice, hemolytic disease, galactosemia, hypothyroidism,
biliary disorders, hypervitaminosis A
● •Older infants, children, adolescents - hemolytic-uremic syndrome, Reye syndrome,
others
■ ØManagement, complications, prevention
● •Supportive care
● •Good hand hygiene, especially with diaper changes
● •Immunoglobulin or HAV vaccine within 2 weeks of exposure
,● •Good personal hygiene; safe drinking water
● •Routine HAV vaccine
○ Hep B: - CORRECT ANSWER: Perinatal transmission can occur
○ Herpes family of viruses - herpes simplex virus - CORRECT ANSWER: ■ Include HSV
1&2, Mononucleosis (EBV), Roseola infantum, varicella
■ ØWidely disseminated in humans
● •HSV-1 - orolabial lesions
● •HSV-2 - genital lesions
■ ØBoth types associated with oral/genital infections
■ ØBoth types devastating to newborns
■ ØType 1 most common in children as gingivostomatitis
■ ØType 2 usually result of sexual activity
■ HSV1 (can give you a genital outbreak but does not like to live there)
■ Should child with HSV1 fever blister be kept out of school?
● No
● Daycare drooling toddlers left out of daycare
● Wrestlers should not compete until lesions cleared
● Ask all pregnant women about HSV
■ Which is not true of HSV2: NOT most common as gingivostomatitis in children. It is:
● Cause of genital lesions
● Usually result of sexual activity
● Devastating to newborns
○ Herpes family of viruses - herpes simplex virus (Cont.) - CORRECT ANSWER: ■
ØNeonatal HSV-2 from mother during delivery
● •Conjunctivae, nose/mouth, broken skin
, ● •Can occur with C-section, asymptomatic shedding
■ ØPostnatal transmission, inoculation from fathers, lateral transmission from other
infants may occur
■ ØPeriod of communicability 2 days to 2 weeks
■ ØSome congenital infections occur >6 weeks
■ ØCan transmit from primary/recurrent infection
■ ØClinical findings - determined by port of entry, age, health, immune competence
■ ØNeonatal infection - always symptomatic
● •Disseminated - multiple organ failure; encephalitis - day 10-12 of life
● •CNS - focal/generalized seizures, lethargy, irritability, poor feeding, herpetic lesions -
day 16-19 of life
● •Skin, eye, mouth - limited to these sites - day 10-12 of life
■ ØTraumatic herpetic infection
● •Localized to area of abrasion, teething, laceration; inoculated by parent who kisses
site
● •Fever, constitutional symptoms, regional lymphadenopathy
■ ØAcute herpetic meningoencephalitis
■ ØRecurrent infection - virus is dormant; recurrent infections are common
■ ØDiagnostic studies
● •Intrapartum cultures mother/child; within 12-24 hours after delivery
■ ØDifferential diagnosis
● •Coxsackievirus if viral stomatitis (hand foot mouth)
● •Always suspect HSV with neonatal respiratory distress/sepsis
■ ØManagement
● •Parenteral acyclovir with life-threatening/neonatal infection
● •Oral acyclovir for 6 months after parenteral treatment
■ ØComplications
● •Most cases mild; may have secondary bacterial infection
