BLD 434 FINAL EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS GRADED A++
The antibody isotype which sensitizes mast cell
IgE
Negative selection occurs in both B and T lymphocytes
True
Match the complement components to the pathway they would initiate when
bound or activated. (iC3/CRP/MBL)
iC3: alternative, CRP: classical ,MBL: lectin
MHC class I presents peptides from _________ antigens.
Endogenous
MHC class II presents endogenous antigens to CD4+ T cells
False
Somatic recombination occurs in:
Both T and B lymphocytes
Negative selection occurs in primary lymphoid tissues.
True
TGF-ß is a characteristic cytokine secreted by what T cell subset
Treg
This process changes the function of the antibody
Isotype switching
, The professional phagocytes are both adaptive immune cells
False
IL-4 will induce differentiation of what T cell phenotype?
Th2
The BEST antibody isotype for opsonization
IgG
Which of the following would be the C3 convertase for the lectin pathway of
complement?
C4b2a
Choose the secondary lymphoid tissues from the list below. MULTIPLE answers
apply and ALL should be chosen
Spleen,Peyer's patch,Lymph nodes, tonsils
Macrophages are considered both professional antigen presenting cells and
professional phagocytes
True
Both alpha beta and gamma delta T lymphocytes express CD3 on their surface
True
Which T lymphocyte type primarily responds to peptide antigens presented by
classical MHC?
Alpha beta T cells
Th1 provide help to:
Cell-mediated immunity
IL-21 is necessary to carry out the function of which T cell subset?
COMPLETE SOLUTIONS GRADED A++
The antibody isotype which sensitizes mast cell
IgE
Negative selection occurs in both B and T lymphocytes
True
Match the complement components to the pathway they would initiate when
bound or activated. (iC3/CRP/MBL)
iC3: alternative, CRP: classical ,MBL: lectin
MHC class I presents peptides from _________ antigens.
Endogenous
MHC class II presents endogenous antigens to CD4+ T cells
False
Somatic recombination occurs in:
Both T and B lymphocytes
Negative selection occurs in primary lymphoid tissues.
True
TGF-ß is a characteristic cytokine secreted by what T cell subset
Treg
This process changes the function of the antibody
Isotype switching
, The professional phagocytes are both adaptive immune cells
False
IL-4 will induce differentiation of what T cell phenotype?
Th2
The BEST antibody isotype for opsonization
IgG
Which of the following would be the C3 convertase for the lectin pathway of
complement?
C4b2a
Choose the secondary lymphoid tissues from the list below. MULTIPLE answers
apply and ALL should be chosen
Spleen,Peyer's patch,Lymph nodes, tonsils
Macrophages are considered both professional antigen presenting cells and
professional phagocytes
True
Both alpha beta and gamma delta T lymphocytes express CD3 on their surface
True
Which T lymphocyte type primarily responds to peptide antigens presented by
classical MHC?
Alpha beta T cells
Th1 provide help to:
Cell-mediated immunity
IL-21 is necessary to carry out the function of which T cell subset?
