https://www.stuvia.com/
TEST BANK FOR MODERN BLOOD BANKING &
x x x x x x x
TRANSFUSION PRACTICES 7TH EDITION BY D
x x x x x
ENISE M HARMENING
x x
9780803668881 CHAPTER 1-
x x
29 COMPLETE GUIDE
x x
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
x x x x x x x x x x
MultiplexChoice
Identifyxthexchoicexthatxbestxcompletesxthexstatementxorxanswersxthexquestion.
1. Whichxmetabolicxpathwayxisxresponsiblexforxgeneratingx90%xofxthexATPxforxthexRBC?
a. Pentosexphosphatexshunt c. Glycolysis
b. Luebering-Rapoportxshunt d.x Methemoglobinxreductase
2. Axunitxofxbloodxwasxreturnedxtoxthexbloodxbankxbeforexitxwasxspiked.xApparentlyxthexpatient’sxIVxfailed.xThex
unitxofxbloodxwasxoutsidexthexbloodxbankxforx35xminutes.xWhichxofxthexstatementsxbelowxisxmostxaccurate?
a. Thexunitxofxbloodxshouldxbexdiscardedximmediately.
b. Thexunitxofxbloodxcanxbexreturnedxtoxinventory.
c. Thexunitxofxbloodxmustxbextransfusedxwithinx4xhoursxorxbexdiscardedxatxthexendxofxthatxtime.
d. Thexunitxofxbloodxmustxbextransfusedxwithx24xhours.
3. Whatxisxthexaveragexdiameterxofxaxplatelet?
a. 5xtox10xµm c. 1xtox2xµm
b. 2xtox4xµm d.x x 4xtox6xµm
4. Inxthexnormalxhemoglobin-
oxygenxdissociationxcurve,xwhatxpercentagexofxoxygenxisxreleasedxtoxthextissuesxwhenxPO2x averagesx40xm
mxHg?
a. 75% c. 100%
b. 25% d.x 50%
5. Whatxfactorsxarexknownxtoxinfluencexplateletxmetabolismxandxfunction?
a. Storagextemperature c. Plateletxcount
b. InitialxpH d.x Allxofxthexabove
6. Whichxofxthexfollowingxredxbloodxcellxmorphologiesxmayxbexpresentxonxthexperipheralxbloodxsmearxasxaxresultx
ofxlossxofxRBCxmembrane?
a. Spherocytes c. Burrxcells
b. Targetxcells d.x Schistocytes
7. Whatxdoesxthextermxautologousxtransfusionxreferxto?
a. Axparentxdonatingxbloodxforxhisxorxherxchild
b. Anxindividualxdonatingxbloodxforxaxfriend
c. Anxindividualxdonatingxbloodxforxaxrelative
d. Anxindividualxdonatingxbloodxforxhisxorxherxownxtransfusion
8. Whatxisxthexprimaryxfunctionxofxhemoglobin?
a. Ironxmetabolism c. Oxygenxtransport
b. Porphyrinxsynthesis d.x Signalxtransduction
9. Allxofxthexfollowingxareasxofxredxbloodxcellxbiologyxarexcrucialxforxnormalxerythrocytexsurvivalx except:
a. Cellularxmetabolism. c. SitexofxthexABOxantigenxattachment.
b. RBCxmembrane. d.x Hemoglobinxstructure.
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x 10.x WhatxisxthexcorrectxbiochemicalxcompositionxofxthexRBCxmembrane?
a. 52%xprotein,x40%xlipid,x8%xcarbohydrate
b. 40%xprotein,x8%xlipid,x52%xcarbohydrate
c. 8%xprotein,x52%xlipid,x40%xcarbohydrate
d. 8%xlipid,x40%xcarbohydrate,x52%xprotein
x 11.x Allxofxthexfollowingxbiochemicalxchangesxarexassociatedxwithxlossxofxredxbloodxcellxviabilityxuponxstorage
except:
a. DecreasedxpH. c. IncreasedxATPxlevel.
b. Lossxofxredxbloodxcellxfunction. d.x Decreasedxglucosexconsumption.
x 12.x Whichxredxbloodxcellxpreservativexhasxaxstoragextimexofx35xdays?
a. ACD c. AS-1
b. CPDA-1 d.x x CPD
x 13.x ThexRBCxmembranexisxrelativelyxpermeablextoxallxofxthexfollowingxexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.x Water.
x 14.xWhatxpercentagexofxplateletsxisxsequesteredxinxthexspleenxasxfunctionalxreservexafterxbeingxreleasedxfromxthex
bonexmarrow?
a. 30% c. 10%
b. 50% d.x x 25%
x 15.x Whatxisxthexmajorxbiochemicalxconsiderationxinxplateletxstorage?
a. Glucosexmetabolism c. Productionxofxcarbonxdioxide
b. Oxygenxsupply d.x RegulationxofxpH
x 16.xWhatxwouldxthexhemoglobin-
oxygenxdissociationxcurvexdepictxinxaxpatientxexhibitingxclinicalxsignsxofxalkalosis?
a. Normal c. Shiftxtoxthexright
b. Shiftxtoxthexleft d.x Nonexofxthexabove
x 17.x Namexthexmainxlipidxcomponentsxofxaxredxbloodxcellxmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.x GlycophorinxA
x 18.x ThexABOxbloodxgroupsxwerexdiscoveredxinx1901xbyxwhom?
a. CharlesxDrew c. LoutitxandxMollison
b. KarlxLandsteiner d.x EdwardxLindeman
x 19.xAxstandingxorderxofxplateletsxwasxshippedxtoxyourxfacilityxbyxyourxsupplier.xItxwasxinadvertentlyxleftxinxthexcor
nerxofxthexdepartmentxuntilxdiscoveredx36xhoursxlater.xWhatxwouldxthexappropriatexactionxbexforxthexbloodxban
ker?
a. Ifxthextemperaturexinxthexboxxwasx22x+/-
x2°CxandxthexplateletxswirlxseemedxOK,xitxwouldxbexOKxtoxacceptxthexunitxintoxinventory.
b. Thexplateletsxhavexfallenxoutsidexthexsupplier’sxqualityxassurance.xThexunitxshouldxbexdis
cardedxbecausexthexpHxhasxprobablyxdroppedxtooxlowxandxplateletxactivationxhasxbeenxco
mpromised.
c. Ifxthextemperaturexwasx1°Cxtox6°CxandxthexplateletxswirlxseemedxOK,xitxwouldxbexOKxto
Thisxstudyxsourcexwasxdownloadedxbyx100000826342158xfromxCourseHero.comxonx09-15-2021x17:54:15xGMTx-
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acceptxthexunitxintoxinventory.
d. IfxthexplateletsxappearedxOKxandxpassedxthexplateletxswirlxtestxafterxbeingxplacedxonxthex
agitator,xtheyxcouldxbexacceptedxintoxthexinventory.
x 20.x Whichxmetabolicxpathwayxpermitsxthexaccumulationxofx2,3xdiphosphoglyceratex(2,3-DPG)?
a. Glycolysis c. Pentosexphosphatexshunt
b. Luebering-Rapoportxshunt d.x Methemoglobinxreductase
x 21.x Allxofxthexfollowingxarexconsistentxwithxax"shiftxtoxthexright"xofxthexhemoglobin-oxygenxdissociationxcurve
except:
a. Increasedx2,3-DPG.
b. 50%xO2x saturationxtoxtissues.
c. Decreasedx2,3-DPG.
d. DecreasedxhemoglobinxaffinityxforxO2.
x 22.x Whatxisxthexnormalxplateletxcountxrangexperxcubicxmillimeter?
a. 100xtox350 c. 50,000xtox200,000
b. 150,000xtox350,000 d.x 350,000xtox500,000
x 23.x Whatxcryoprotectivexagentxisxaddedxtoxredxbloodxcellsxuponxfreezing?
a. Dextrose c. Glycerol
b. Adsol d.x Allxofxthexabove
x 24.x Ifxplateletsxarextoxbexstoredxforx5xdaysxonxaxrotator,xwhatxisxthexoptimalxstoragextemperature?
a. 1°Cxtox6°C c. 35°Cxtox37°C
b. 20°Cxtox24°C d.x 1°Cxtox10°C
x 25.x Whatxrolexdoxplateletsxplayxinxhemostasis?
a. Maintenancexofxvascularxintegrity
b. Initialxarrestxofxbleedingxbyxplateletxplugxformation
c. Stabilizationxofxthexhemostaticxplug
d. Allxofxthexabove
x 26.x Whichxofxthexfollowingxbestxdescribesx"integral"xmembranexproteins?
a. Residexatxthexcytoplasmicxsurfacexofxmembrane
b. Spanxthexentirexmembranexsurface
c. Formxthexredxbloodxcellxcytoskeleton
d. Nonexofxthexabove
x 27.x Howxisxstroma-freexhemoglobinxsolutionxprepared?
a. Outdatedxredxbloodxcellsxarexconcentrated,xandxstromaxisxremoved.
b. Outdatedxredxbloodxcellsxarexdilutedxwithxsaline,xandxstromaxisxremoved.
c. Outdatedxredxbloodxcellsxarexlysed,xandxstromaxisxremoved.
d. Nonexofxthexabove
x 28.x WhatxisxthexnormalxlifexspanxofxanxRBC?
a. 100xdays c. 120xhours
b. 120xdays d.x 2xdays
x 29.x RegardingxlossxofxRBCxmembranexdeformability,xallxofxthexfollowingxarextruexexcept:
a. IncreasexinxATPxlevel.
b. DecreasexinxATPxlevel.
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TEST BANK FOR MODERN BLOOD BANKING &
x x x x x x x
TRANSFUSION PRACTICES 7TH EDITION BY D
x x x x x
ENISE M HARMENING
x x
9780803668881 CHAPTER 1-
x x
29 COMPLETE GUIDE
x x
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
x x x x x x x x x x
MultiplexChoice
Identifyxthexchoicexthatxbestxcompletesxthexstatementxorxanswersxthexquestion.
1. Whichxmetabolicxpathwayxisxresponsiblexforxgeneratingx90%xofxthexATPxforxthexRBC?
a. Pentosexphosphatexshunt c. Glycolysis
b. Luebering-Rapoportxshunt d.x Methemoglobinxreductase
2. Axunitxofxbloodxwasxreturnedxtoxthexbloodxbankxbeforexitxwasxspiked.xApparentlyxthexpatient’sxIVxfailed.xThex
unitxofxbloodxwasxoutsidexthexbloodxbankxforx35xminutes.xWhichxofxthexstatementsxbelowxisxmostxaccurate?
a. Thexunitxofxbloodxshouldxbexdiscardedximmediately.
b. Thexunitxofxbloodxcanxbexreturnedxtoxinventory.
c. Thexunitxofxbloodxmustxbextransfusedxwithinx4xhoursxorxbexdiscardedxatxthexendxofxthatxtime.
d. Thexunitxofxbloodxmustxbextransfusedxwithx24xhours.
3. Whatxisxthexaveragexdiameterxofxaxplatelet?
a. 5xtox10xµm c. 1xtox2xµm
b. 2xtox4xµm d.x x 4xtox6xµm
4. Inxthexnormalxhemoglobin-
oxygenxdissociationxcurve,xwhatxpercentagexofxoxygenxisxreleasedxtoxthextissuesxwhenxPO2x averagesx40xm
mxHg?
a. 75% c. 100%
b. 25% d.x 50%
5. Whatxfactorsxarexknownxtoxinfluencexplateletxmetabolismxandxfunction?
a. Storagextemperature c. Plateletxcount
b. InitialxpH d.x Allxofxthexabove
6. Whichxofxthexfollowingxredxbloodxcellxmorphologiesxmayxbexpresentxonxthexperipheralxbloodxsmearxasxaxresultx
ofxlossxofxRBCxmembrane?
a. Spherocytes c. Burrxcells
b. Targetxcells d.x Schistocytes
7. Whatxdoesxthextermxautologousxtransfusionxreferxto?
a. Axparentxdonatingxbloodxforxhisxorxherxchild
b. Anxindividualxdonatingxbloodxforxaxfriend
c. Anxindividualxdonatingxbloodxforxaxrelative
d. Anxindividualxdonatingxbloodxforxhisxorxherxownxtransfusion
8. Whatxisxthexprimaryxfunctionxofxhemoglobin?
a. Ironxmetabolism c. Oxygenxtransport
b. Porphyrinxsynthesis d.x Signalxtransduction
9. Allxofxthexfollowingxareasxofxredxbloodxcellxbiologyxarexcrucialxforxnormalxerythrocytexsurvivalx except:
a. Cellularxmetabolism. c. SitexofxthexABOxantigenxattachment.
b. RBCxmembrane. d.x Hemoglobinxstructure.
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x 10.x WhatxisxthexcorrectxbiochemicalxcompositionxofxthexRBCxmembrane?
a. 52%xprotein,x40%xlipid,x8%xcarbohydrate
b. 40%xprotein,x8%xlipid,x52%xcarbohydrate
c. 8%xprotein,x52%xlipid,x40%xcarbohydrate
d. 8%xlipid,x40%xcarbohydrate,x52%xprotein
x 11.x Allxofxthexfollowingxbiochemicalxchangesxarexassociatedxwithxlossxofxredxbloodxcellxviabilityxuponxstorage
except:
a. DecreasedxpH. c. IncreasedxATPxlevel.
b. Lossxofxredxbloodxcellxfunction. d.x Decreasedxglucosexconsumption.
x 12.x Whichxredxbloodxcellxpreservativexhasxaxstoragextimexofx35xdays?
a. ACD c. AS-1
b. CPDA-1 d.x x CPD
x 13.x ThexRBCxmembranexisxrelativelyxpermeablextoxallxofxthexfollowingxexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.x Water.
x 14.xWhatxpercentagexofxplateletsxisxsequesteredxinxthexspleenxasxfunctionalxreservexafterxbeingxreleasedxfromxthex
bonexmarrow?
a. 30% c. 10%
b. 50% d.x x 25%
x 15.x Whatxisxthexmajorxbiochemicalxconsiderationxinxplateletxstorage?
a. Glucosexmetabolism c. Productionxofxcarbonxdioxide
b. Oxygenxsupply d.x RegulationxofxpH
x 16.xWhatxwouldxthexhemoglobin-
oxygenxdissociationxcurvexdepictxinxaxpatientxexhibitingxclinicalxsignsxofxalkalosis?
a. Normal c. Shiftxtoxthexright
b. Shiftxtoxthexleft d.x Nonexofxthexabove
x 17.x Namexthexmainxlipidxcomponentsxofxaxredxbloodxcellxmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.x GlycophorinxA
x 18.x ThexABOxbloodxgroupsxwerexdiscoveredxinx1901xbyxwhom?
a. CharlesxDrew c. LoutitxandxMollison
b. KarlxLandsteiner d.x EdwardxLindeman
x 19.xAxstandingxorderxofxplateletsxwasxshippedxtoxyourxfacilityxbyxyourxsupplier.xItxwasxinadvertentlyxleftxinxthexcor
nerxofxthexdepartmentxuntilxdiscoveredx36xhoursxlater.xWhatxwouldxthexappropriatexactionxbexforxthexbloodxban
ker?
a. Ifxthextemperaturexinxthexboxxwasx22x+/-
x2°CxandxthexplateletxswirlxseemedxOK,xitxwouldxbexOKxtoxacceptxthexunitxintoxinventory.
b. Thexplateletsxhavexfallenxoutsidexthexsupplier’sxqualityxassurance.xThexunitxshouldxbexdis
cardedxbecausexthexpHxhasxprobablyxdroppedxtooxlowxandxplateletxactivationxhasxbeenxco
mpromised.
c. Ifxthextemperaturexwasx1°Cxtox6°CxandxthexplateletxswirlxseemedxOK,xitxwouldxbexOKxto
Thisxstudyxsourcexwasxdownloadedxbyx100000826342158xfromxCourseHero.comxonx09-15-2021x17:54:15xGMTx-
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acceptxthexunitxintoxinventory.
d. IfxthexplateletsxappearedxOKxandxpassedxthexplateletxswirlxtestxafterxbeingxplacedxonxthex
agitator,xtheyxcouldxbexacceptedxintoxthexinventory.
x 20.x Whichxmetabolicxpathwayxpermitsxthexaccumulationxofx2,3xdiphosphoglyceratex(2,3-DPG)?
a. Glycolysis c. Pentosexphosphatexshunt
b. Luebering-Rapoportxshunt d.x Methemoglobinxreductase
x 21.x Allxofxthexfollowingxarexconsistentxwithxax"shiftxtoxthexright"xofxthexhemoglobin-oxygenxdissociationxcurve
except:
a. Increasedx2,3-DPG.
b. 50%xO2x saturationxtoxtissues.
c. Decreasedx2,3-DPG.
d. DecreasedxhemoglobinxaffinityxforxO2.
x 22.x Whatxisxthexnormalxplateletxcountxrangexperxcubicxmillimeter?
a. 100xtox350 c. 50,000xtox200,000
b. 150,000xtox350,000 d.x 350,000xtox500,000
x 23.x Whatxcryoprotectivexagentxisxaddedxtoxredxbloodxcellsxuponxfreezing?
a. Dextrose c. Glycerol
b. Adsol d.x Allxofxthexabove
x 24.x Ifxplateletsxarextoxbexstoredxforx5xdaysxonxaxrotator,xwhatxisxthexoptimalxstoragextemperature?
a. 1°Cxtox6°C c. 35°Cxtox37°C
b. 20°Cxtox24°C d.x 1°Cxtox10°C
x 25.x Whatxrolexdoxplateletsxplayxinxhemostasis?
a. Maintenancexofxvascularxintegrity
b. Initialxarrestxofxbleedingxbyxplateletxplugxformation
c. Stabilizationxofxthexhemostaticxplug
d. Allxofxthexabove
x 26.x Whichxofxthexfollowingxbestxdescribesx"integral"xmembranexproteins?
a. Residexatxthexcytoplasmicxsurfacexofxmembrane
b. Spanxthexentirexmembranexsurface
c. Formxthexredxbloodxcellxcytoskeleton
d. Nonexofxthexabove
x 27.x Howxisxstroma-freexhemoglobinxsolutionxprepared?
a. Outdatedxredxbloodxcellsxarexconcentrated,xandxstromaxisxremoved.
b. Outdatedxredxbloodxcellsxarexdilutedxwithxsaline,xandxstromaxisxremoved.
c. Outdatedxredxbloodxcellsxarexlysed,xandxstromaxisxremoved.
d. Nonexofxthexabove
x 28.x WhatxisxthexnormalxlifexspanxofxanxRBC?
a. 100xdays c. 120xhours
b. 120xdays d.x 2xdays
x 29.x RegardingxlossxofxRBCxmembranexdeformability,xallxofxthexfollowingxarextruexexcept:
a. IncreasexinxATPxlevel.
b. DecreasexinxATPxlevel.
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